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Comparative GO Graph (mouse, human, rat)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Oas1b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Oas1b
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:00017302'-5'-oligoadenylate synthetase activityOAS1IDAHumanPMID:12799444
Molecular FunctionGO:00017302'-5'-oligoadenylate synthetase activityOAS1IDAHumanPMID:2434505
Molecular FunctionGO:00017302'-5'-oligoadenylate synthetase activityOAS1IDAHumanPMID:25275129
Molecular FunctionGO:0003725double-stranded RNA bindingOAS1IDAHumanPMID:12799444
Molecular FunctionGO:0003725double-stranded RNA bindingOAS1IDAHumanPMID:23319625
Molecular FunctionGO:0003725double-stranded RNA bindingOAS1IDAHumanPMID:25275129
Molecular FunctionGO:0003725double-stranded RNA bindingOas1bIDAMousePMID:12396720
Molecular FunctionGO:0005515protein bindingOAS1IPIUniProtKB:O89168HumanPMID:15039538
Molecular FunctionGO:0005515protein bindingOAS1IPIUniProtKB:Q96LA8HumanPMID:23455924
Molecular FunctionGO:0005515protein bindingOAS1IPIUniProtKB:O00471HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingOAS1IPIUniProtKB:P12814HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingOAS1IPIUniProtKB:P14373HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingOAS1IPIUniProtKB:P12814HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingOAS1IPIUniProtKB:P14373HumanPMID:31515488
Cellular ComponentGO:0005737cytoplasmOAS1IDAHumanPMID:21245038
Cellular ComponentGO:0005829cytosolOAS1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005654nucleoplasmOAS1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusOAS1IDAHumanPMID:2434505
Biological ProcessGO:0140374antiviral innate immune responseOAS1IEPHumanPMID:25930096
Biological ProcessGO:0140374antiviral innate immune responseOAS1IDAHumanPMID:34581622
Biological ProcessGO:0035458cellular response to interferon-betaOAS1IDAHumanPMID:2434505
Biological ProcessGO:0098586cellular response to virusOAS1IEPHumanPMID:28146100
Biological ProcessGO:0042742defense response to bacteriumOAS1IMPHumanPMID:30822544
Biological ProcessGO:0051607defense response to virusOAS1IDAHumanPMID:23196181
Biological ProcessGO:0042593glucose homeostasisOAS1IMPHumanPMID:23575436
Biological ProcessGO:0006006glucose metabolic processOAS1IMPHumanPMID:23575436
Biological ProcessGO:0070106interleukin-27-mediated signaling pathwayOAS1IEPHumanPMID:32270034
Biological ProcessGO:2000342negative regulation of chemokine (C-X-C motif) ligand 2 productionOAS1IMPHumanPMID:30078389
Biological ProcessGO:0071659negative regulation of IP-10 productionOAS1IMPHumanPMID:30078389
Biological ProcessGO:0060339negative regulation of type I interferon-mediated signaling pathwayOAS1IMPHumanPMID:30078389
Biological ProcessGO:0045071negative regulation of viral genome replicationOAS1IDAHumanPMID:18931074
Biological ProcessGO:0032728positive regulation of interferon-beta productionOAS1IMPHumanPMID:30822544
Biological ProcessGO:0071639positive regulation of monocyte chemotactic protein-1 productionOAS1IMPHumanPMID:30822544
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionOAS1IMPHumanPMID:30822544
Biological ProcessGO:0060700regulation of ribonuclease activityOAS1IDAHumanPMID:25275129
Biological ProcessGO:0009615response to virusOAS1IDAHumanPMID:18931074
Biological ProcessGO:0009615response to virusOas1bIDAMousePMID:12080145
Biological ProcessGO:0043129surfactant homeostasisOAS1IMPHumanPMID:29455859
Biological ProcessGO:0034138toll-like receptor 3 signaling pathwayOAS1IMPHumanPMID:30078389
Biological ProcessGO:0034142toll-like receptor 4 signaling pathwayOAS1IMPHumanPMID:30078389

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory