Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OAS2
  • Mouse genes Oas2
  • Rat genes Oas2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Oas2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	OAS2	IMP		Human	PMID:10464285
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	OAS2	IDA		Human	PMID:9880569
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	Oas2	IDA		Mouse	MGI:MGI:6094812|PMID:29117179
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	Oas2	IDA		Mouse	PMID:12396720
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	Oas2	IDA		Mouse	PMID:15865429
Molecular Function	GO:0005524	ATP binding	OAS2	IMP		Human	PMID:10464285
Molecular Function	GO:0003725	double-stranded RNA binding	OAS2	IMP		Human	PMID:10464285
Molecular Function	GO:0003725	double-stranded RNA binding	OAS2	IDA		Human	PMID:9880569
Molecular Function	GO:0003725	double-stranded RNA binding	Oas2	IDA		Mouse	PMID:12396720
Molecular Function	GO:0005515	protein binding	OAS2	IPI	UniProtKB:P49761	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OAS2	IPI	UniProtKB:P49761	Human	PMID:31515488
Cellular Component	GO:0016020	membrane	OAS2	HDA		Human	PMID:19946888
Cellular Component	GO:0048471	perinuclear region of cytoplasm	OAS2	IDA		Human	PMID:19923450
Biological Process	GO:0042742	defense response to bacterium	OAS2	IMP		Human	PMID:30822544
Biological Process	GO:0051607	defense response to virus	Oas2	IDA		Mouse	MGI:MGI:6094812|PMID:29117179
Biological Process	GO:0070106	interleukin-27-mediated signaling pathway	OAS2	IDA		Human	PMID:32270034
Biological Process	GO:0070106	interleukin-27-mediated signaling pathway	Oas2	IEP		Mouse	MGI:MGI:6415954|PMID:32270034
Biological Process	GO:0032728	positive regulation of interferon-beta production	OAS2	IMP		Human	PMID:30822544
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	OAS2	IMP		Human	PMID:30822544
Biological Process	GO:1903487	regulation of lactation	Oas2	IMP		Mouse	MGI:MGI:6094812|PMID:29117179
Biological Process	GO:0009617	response to bacterium	Oas2	IEP		Mouse	PMID:23012479
Biological Process	GO:0006401	RNA catabolic process	Oas2	IDA		Mouse	PMID:15865429
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	Oas2	IDA		Mouse	MGI:MGI:6094812|PMID:29117179

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern