Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OBSCN
  • Mouse genes Obscn
  • Rat genes Obscn
  • Zfish genes obscna,obscnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Obscn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030506	ankyrin binding	OBSCN	IPI	UniProtKB:Q01484	Human	PMID:18782775
Molecular Function	GO:0045296	cadherin binding	Obscn	IPI	UniProtKB:P15116	Mouse	MGI:MGI:5494790|PMID:23392350
Molecular Function	GO:1902936	phosphatidylinositol bisphosphate binding	Obscn	IDA		Mouse	MGI:MGI:6101642|PMID:28826662
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	OBSCN	IDA		Human	PMID:28826662
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	OBSCN	IDA		Human	PMID:28826662
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	OBSCN	IDA		Human	PMID:28826662
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	OBSCN	IDA		Human	PMID:28826662
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	OBSCN	IDA		Human	PMID:28826662
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	OBSCN	IDA		Human	PMID:28826662
Molecular Function	GO:0005515	protein binding	OBSCN	IPI	UniProtKB:Q8WZ42	Human	PMID:11448995
Molecular Function	GO:0005515	protein binding	OBSCN	IPI	UniProtKB:Q8WZ42	Human	PMID:20133654
Molecular Function	GO:0005515	protein binding	OBSCN	IPI	UniProtKB:Q8WZ42	Human	PMID:20489725
Molecular Function	GO:0005515	protein binding	OBSCN	IPI	UniProtKB:Q8WZ42	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	Obscn	IPI	UniProtKB:P14094	Mouse	MGI:MGI:5494790|PMID:23392350
Molecular Function	GO:0005515	protein binding	Obscn	IPI	RGD:1309620	Rat	PMID:12631729|RGD:633514
Molecular Function	GO:0004672	protein kinase activity	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Molecular Function	GO:0031432	titin binding	OBSCN	IPI	UniProtKB:Q8WZ42-6	Human	PMID:11717165
Cellular Component	GO:0005829	cytosol	OBSCN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Cellular Component	GO:0014704	intercalated disc	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Cellular Component	GO:0031430	M band	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Cellular Component	GO:0031430	M band	Obscn	IDA		Mouse	MGI:MGI:3822951|PMID:18782775
Cellular Component	GO:0031430	M band	Obscn	IDA		Rat	PMID:12631729|RGD:633514
Cellular Component	GO:0031430	M band	Obscn	IDA		Rat	PMID:16625317|RGD:1600574
Cellular Component	GO:0031430	M band	obscnb	IDA		Zfish	PMID:16779859
Cellular Component	GO:0016604	nuclear body	OBSCN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	OBSCN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Obscn	IDA		Mouse	MGI:MGI:6101642|PMID:28826662
Cellular Component	GO:0042383	sarcolemma	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Cellular Component	GO:0030017	sarcomere	Obscn	IDA		Rat	PMID:12631729|RGD:633514
Cellular Component	GO:0030018	Z disc	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Cellular Component	GO:0030018	Z disc	Obscn	IDA		Rat	PMID:12631729|RGD:633514
Cellular Component	GO:0030018	Z disc	Obscn	IDA		Rat	PMID:16625317|RGD:1600574
Cellular Component	GO:0030018	Z disc	obscna	IDA		Zfish	PMID:16779859
Biological Process	GO:0030239	myofibril assembly	obscnb	IMP	ZFIN:ZDB-MRPHLNO-070121-1	Zfish	PMID:16779859
Biological Process	GO:0030239	myofibril assembly	obscnb	IMP	ZFIN:ZDB-MRPHLNO-070122-1	Zfish	PMID:16779859
Biological Process	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	Obscn	IDA		Mouse	MGI:MGI:6101642|PMID:28826662
Biological Process	GO:0046777	protein autophosphorylation	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Biological Process	GO:0006468	protein phosphorylation	Obscn	IDA		Mouse	MGI:MGI:5494790|PMID:23392350
Biological Process	GO:0060041	retina development in camera-type eye	obscnb	IMP	ZFIN:ZDB-MRPHLNO-100524-1,ZFIN:ZDB-MRPHLNO-100524-2	Zfish	PMID:19931525
Biological Process	GO:0014866	skeletal myofibril assembly	obscnb	IMP	ZFIN:ZDB-MRPHLNO-070122-1	Zfish	PMID:22190853
Biological Process	GO:0055002	striated muscle cell development	obscnb	IMP	ZFIN:ZDB-MRPHLNO-100524-1,ZFIN:ZDB-MRPHLNO-100524-2	Zfish	PMID:19931525
Biological Process	GO:0055002	striated muscle cell development	obscnb	IMP	ZFIN:ZDB-MRPHLNO-070122-1	Zfish	PMID:16779859
Biological Process	GO:0055002	striated muscle cell development	obscnb	IMP	ZFIN:ZDB-MRPHLNO-070122-1	Zfish	PMID:19931525
Biological Process	GO:0055002	striated muscle cell development	obscnb	IMP	ZFIN:ZDB-MRPHLNO-070121-1	Zfish	PMID:16779859

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern