Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ocln

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes OCLN
- Mouse genes Ocln
- Rat genes Ocln
- Zfish genes oclna,oclnb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ocln

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:P49674	Human	PMID:16616143
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:Q07157	Human	PMID:19332538
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:O75508\|UniProtKB:O95484\|UniProtKB:O95832\|UniProtKB:P56747\|UniProtKB:P56749\|UniProtKB:P56750	Human	PMID:20375010
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:O15162	Human	PMID:21806988
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:P49674	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:Q8N205	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:Q9BXN2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:O95832	Human	PMID:26607202
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:P16284	Human	PMID:26607202
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:Q96AP7	Human	PMID:26607202
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:P49674	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:P19404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	OCLN	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ocln	IPI	UniProtKB:B5TVM2\|UniProtKB:Q8CBR1\|UniProtKB:Q99KG5	Mouse	MGI:MGI:5507911\|PMID:23239027
Molecular Function	GO:0005515	protein binding	Ocln	IPI	PR:Q8C863	Mouse	PMID:11782481
Molecular Function	GO:0005515	protein binding	Ocln	IPI	UniProtKB:F1M4A0	Rat	PMID:19470647\|RGD:13432232
Molecular Function	GO:0005515	protein binding	Ocln	IPI	UniProtKB:O35346	Rat	PMID:19470647\|RGD:13432232
Molecular Function	GO:0005515	protein binding	Ocln	IPI	UniProtKB:F1M4A0	Rat	PMID:22106313\|RGD:13432329
Molecular Function	GO:0005515	protein binding	Ocln	IPI	UniProtKB:O35346	Rat	PMID:22106313\|RGD:13432329
Molecular Function	GO:0019904	protein domain specific binding	OCLN	IPI	UniProtKB:Q07157	Human	PMID:20164257
Cellular Component	GO:0016324	apical plasma membrane	Ocln	IDA		Mouse	PMID:20089884
Cellular Component	GO:0016324	apical plasma membrane	Ocln	IDA		Rat	PMID:22001439\|RGD:8655996
Cellular Component	GO:0016327	apicolateral plasma membrane	Ocln	IDA		Mouse	PMID:16520537
Cellular Component	GO:0005923	bicellular tight junction	OCLN	IDA		Human	PMID:20028514
Cellular Component	GO:0005923	bicellular tight junction	OCLN	IDA		Human	PMID:20164257
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	MGI:MGI:5805359\|PMID:25617501
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:11025210
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:17666436
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:19129494
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:15775979
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:17000770
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:17130295
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:24889144
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:22946046
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:16651389
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:16520537
Cellular Component	GO:0005923	bicellular tight junction	Ocln	IDA		Mouse	PMID:14685273
Cellular Component	GO:0030054	cell junction	OCLN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030054	cell junction	OCLN	IDA		Human	PMID:24567356
Cellular Component	GO:0005911	cell-cell junction	OCLN	IDA		Human	PMID:19332538
Cellular Component	GO:0005911	cell-cell junction	OCLN	IDA		Human	PMID:21415414
Cellular Component	GO:0005911	cell-cell junction	OCLN	IDA		Human	PMID:23288152
Cellular Component	GO:0005911	cell-cell junction	Ocln	IDA		Mouse	MGI:MGI:6368952\|PMID:12734665
Cellular Component	GO:0005911	cell-cell junction	Ocln	IDA		Mouse	PMID:16365161
Cellular Component	GO:0031410	cytoplasmic vesicle	OCLN	IDA		Human	PMID:20164257
Cellular Component	GO:0030139	endocytic vesicle	Ocln	IDA		Mouse	MGI:MGI:5508273\|PMID:15528189
Cellular Component	GO:0016328	lateral plasma membrane	Ocln	IDA		Rat	PMID:22001439\|RGD:8655996
Cellular Component	GO:0005765	lysosomal membrane	OCLN	IDA		Human	PMID:28718701
Cellular Component	GO:0005886	plasma membrane	OCLN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	OCLN	IDA		Human	PMID:11090614
Cellular Component	GO:0005886	plasma membrane	Ocln	IDA		Mouse	MGI:MGI:5508273\|PMID:15528189
Cellular Component	GO:0005886	plasma membrane	Ocln	IDA		Mouse	PMID:11782481
Cellular Component	GO:0005886	plasma membrane	Ocln	IDA		Mouse	PMID:12498716
Cellular Component	GO:0005886	plasma membrane	Ocln	IDA		Mouse	PMID:15775979
Cellular Component	GO:0005886	plasma membrane	Ocln	IDA		Mouse	PMID:12060405
Cellular Component	GO:0032991	protein-containing complex	OCLN	IDA		Human	PMID:26607202
Cellular Component	GO:0070160	tight junction	OCLN	IMP		Human	PMID:24854121
Cellular Component	GO:0070160	tight junction	OCLN	IDA		Human	PMID:30734065
Cellular Component	GO:0070160	tight junction	Ocln	IDA		Mouse	MGI:MGI:6369916\|PMID:30734065
Cellular Component	GO:0070160	tight junction	Ocln	IDA		Mouse	MGI:MGI:5507911\|PMID:23239027
Biological Process	GO:0070830	bicellular tight junction assembly	OCLN	IMP		Human	PMID:20164257
Biological Process	GO:0070830	bicellular tight junction assembly	OCLN	IMP		Human	PMID:26607202
Biological Process	GO:0045216	cell-cell junction organization	OCLN	IMP		Human	PMID:20164257
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Ocln	IEP		Rat	PMID:21748286\|RGD:11341809
Biological Process	GO:0010629	negative regulation of gene expression	OCLN	IMP		Human	PMID:21415414
Biological Process	GO:0010629	negative regulation of gene expression	Ocln	IMP		Mouse	MGI:MGI:6368048\|PMID:21415414
Biological Process	GO:0001933	negative regulation of protein phosphorylation	OCLN	IMP		Human	PMID:28718701
Biological Process	GO:1905605	positive regulation of blood-brain barrier permeability	OCLN	IMP		Human	PMID:24854121
Biological Process	GO:0010628	positive regulation of gene expression	OCLN	IMP		Human	PMID:28718701
Biological Process	GO:0046326	positive regulation of glucose import	OCLN	IMP		Human	PMID:28718701
Biological Process	GO:0010827	regulation of glucose transmembrane transport	OCLN	IMP		Human	PMID:28718701
Biological Process	GO:0140459	response to Gram-positive bacterium	Ocln	IEP		Rat	PMID:20501441\|RGD:2324672
Biological Process	GO:0070673	response to interleukin-18	Ocln	IMP		Rat	PMID:22001439\|RGD:8655996
Biological Process	GO:0120193	tight junction organization	Ocln	IMP		Mouse	MGI:MGI:6369916\|PMID:30734065

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.