Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OCRL
  • Mouse genes Ocrl
  • Rat genes Ocrl
  • Zfish genes ocrl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ocrl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	OCRL	IDA		Human	PMID:12915445
Molecular Function	GO:0052745	inositol phosphate phosphatase activity	OCRL	IDA		Human	PMID:25869668
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Ocrl	IDA		Mouse	PMID:9593760
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	ocrl	IMP	ZFIN:ZDB-GENO-120531-1	Zfish	PMID:22210625
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P63000	Human	PMID:12915445
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P20339	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P20340	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P61006	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P61106	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P62820	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q00610	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P11442	Human	PMID:19536138
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q00610	Human	PMID:19536138
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q6ICB4	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q8N4B1	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q9UKG1	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P20339	Human	PMID:21378754
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P20340	Human	PMID:21378754
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P61006	Human	PMID:21378754
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q9H0U4	Human	PMID:21378754
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P61006	Human	PMID:22543976
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P20339	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P20340	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P62820	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q00610	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q68FD5	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q91VH2	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q9H0U4	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q9Y5X1	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P32019|UniProtKB:Q96PE3	Human	PMID:25869668
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q8CDA1,UniProtKB:Q9CQD1	Human	PMID:25869668
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:Q00610	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P61006	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	OCRL	IPI	UniProtKB:P61006	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	Ocrl	IPI	RGD:628598	Rat	PMID:19795375|RGD:11534006
Molecular Function	GO:0031267	small GTPase binding	OCRL	IPI	UniProtKB:P63000	Human	PMID:12915445
Cellular Component	GO:0030136	clathrin-coated vesicle	OCRL	IDA		Human	PMID:21233288
Cellular Component	GO:0030136	clathrin-coated vesicle	OCRL	IDA		Human	PMID:25869668
Cellular Component	GO:0005737	cytoplasm	OCRL	IDA		Human	PMID:12915445
Cellular Component	GO:0005769	early endosome	OCRL	IDA		Human	PMID:21233288
Cellular Component	GO:0005769	early endosome	OCRL	IDA		Human	PMID:25869668
Cellular Component	GO:0005634	nucleus	OCRL	IDA		Human	PMID:12915445
Cellular Component	GO:0001750	photoreceptor outer segment	OCRL	IDA		Human	PMID:22543976
Cellular Component	GO:0005886	plasma membrane	OCRL	IDA		Human	PMID:12915445
Cellular Component	GO:0005802	trans-Golgi network	OCRL	IDA		Human	PMID:12915445
Biological Process	GO:0007420	brain development	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120405-1	Zfish	PMID:22210625
Biological Process	GO:0007420	brain development	ocrl	IMP	ZFIN:ZDB-GENO-120531-1	Zfish	PMID:22210625
Biological Process	GO:0043009	chordate embryonic development	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-1	Zfish	PMID:22680056
Biological Process	GO:0060271	cilium assembly	OCRL	IMP		Human	PMID:22228094
Biological Process	GO:0060271	cilium assembly	OCRL	IMP		Human	PMID:22543976
Biological Process	GO:0060271	cilium assembly	ocrl	IMP	ZFIN:ZDB-GENO-120531-1	Zfish	PMID:25838181
Biological Process	GO:0060271	cilium assembly	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-1	Zfish	PMID:22543976
Biological Process	GO:0003341	cilium movement	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-2	Zfish	PMID:22228094
Biological Process	GO:0044782	cilium organization	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-1	Zfish	PMID:22680056
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-2	Zfish	PMID:22228094
Biological Process	GO:0006897	endocytosis	ocrl	IMP	ZFIN:ZDB-GENO-120531-1	Zfish	PMID:25838181
Biological Process	GO:0006897	endocytosis	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120405-1	Zfish	PMID:25838181
Biological Process	GO:0006897	endocytosis	ocrl	IGI	ZFIN:ZDB-GENO-120531-1,ZFIN:ZDB-MRPHLNO-150602-1	Zfish	PMID:25838181
Biological Process	GO:0001701	in utero embryonic development	Ocrl	IGI	MGI:MGI:103257	Mouse	PMID:20195868
Biological Process	GO:0032402	melanosome transport	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-1	Zfish	PMID:23805271
Biological Process	GO:0001755	neural crest cell migration	ocrl	IMP	ZFIN:ZDB-GENO-050913-2,ZFIN:ZDB-MRPHLNO-120409-2	Zfish	PMID:22228094
Biological Process	GO:0048884	neuromast development	ocrl	IMP	ZFIN:ZDB-GENO-120531-1	Zfish	PMID:22228094
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Ocrl	IDA		Mouse	PMID:9593760
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	ocrl	IMP	ZFIN:ZDB-GENO-120531-1	Zfish	PMID:22210625
Biological Process	GO:0043473	pigmentation	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-2	Zfish	PMID:22228094
Biological Process	GO:0035776	pronephric proximal tubule development	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-1	Zfish	PMID:31676724
Biological Process	GO:0035776	pronephric proximal tubule development	ocrl	IMP	ZFIN:ZDB-GENO-120531-1	Zfish	PMID:31676724
Biological Process	GO:0030100	regulation of endocytosis	ocrl	IMP	ZFIN:ZDB-GENO-221019-3	Zfish	PMID:34673953
Biological Process	GO:0030100	regulation of endocytosis	ocrl	IGI	ZFIN:ZDB-GENO-221019-3,ZFIN:ZDB-MRPHLNO-221012-1	Zfish	PMID:34673953
Biological Process	GO:0030100	regulation of endocytosis	ocrl	IGI	ZFIN:ZDB-GENO-221019-1,ZFIN:ZDB-MRPHLNO-120405-1	Zfish	PMID:34673953
Biological Process	GO:0030100	regulation of endocytosis	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120405-1	Zfish	PMID:34673953
Biological Process	GO:0043087	regulation of GTPase activity	OCRL	IDA		Human	PMID:12915445
Biological Process	GO:0097205	renal filtration	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-1	Zfish	PMID:22680056
Biological Process	GO:0071871	response to epinephrine	ocrl	IMP	ZFIN:ZDB-MRPHLNO-120409-1	Zfish	PMID:23805271

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern