Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OGDH
  • Mouse genes Ogdh
  • Rat genes Ogdh
  • Zfish genes ogdha,ogdhb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ogdh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031072	heat shock protein binding	Ogdh	IPI	RGD:621314	Rat	PMID:9811814|RGD:2298706
Molecular Function	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	Ogdh	IDA		Mouse	PMID:17322295
Molecular Function	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	OGDH	IDA		Human	PMID:24495017
Molecular Function	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	OGDH	IDA		Human	PMID:29211711
Molecular Function	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	Ogdh	IDA		Rat	PMID:9712727|RGD:2306877
Molecular Function	GO:0005515	protein binding	OGDH	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	OGDH	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0051087	protein-folding chaperone binding	Ogdh	IPI	RGD:621314	Rat	PMID:9811814|RGD:2298706
Molecular Function	GO:0030976	thiamine pyrophosphate binding	OGDH	IDA		Human	PMID:24495017
Cellular Component	GO:0005739	mitochondrion	OGDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	OGDH	IDA		Human	PMID:29211711
Cellular Component	GO:0005739	mitochondrion	Ogdh	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ogdh	IDA		Mouse	PMID:17322295
Cellular Component	GO:0005739	mitochondrion	Ogdh	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ogdh	IDA		Rat	PMID:3571202|RGD:2306876
Cellular Component	GO:0005739	mitochondrion	Ogdh	IDA		Rat	PMID:9712727|RGD:2306877
Cellular Component	GO:0005739	mitochondrion	Ogdh	IDA		Rat	PMID:9811814|RGD:2298706
Cellular Component	GO:0005634	nucleus	OGDH	IDA		Human	PMID:29211711
Cellular Component	GO:0045252	oxoglutarate dehydrogenase complex	OGDH	IDA		Human	PMID:29211711
Cellular Component	GO:0045252	oxoglutarate dehydrogenase complex	Ogdh	IMP		Mouse	PMID:22169199
Cellular Component	GO:0045252	oxoglutarate dehydrogenase complex	Ogdh	IDA		Rat	PMID:3571202|RGD:2306876
Biological Process	GO:0006103	2-oxoglutarate metabolic process	OGDH	IDA		Human	PMID:24495017
Biological Process	GO:0006103	2-oxoglutarate metabolic process	OGDH	IDA		Human	PMID:29211711
Biological Process	GO:0006103	2-oxoglutarate metabolic process	Ogdh	IDA		Rat	PMID:3571202|RGD:2306876
Biological Process	GO:0006103	2-oxoglutarate metabolic process	Ogdh	IDA		Rat	PMID:9712727|RGD:2306877
Biological Process	GO:0021695	cerebellar cortex development	Ogdh	IEP		Mouse	MGI:MGI:3662936|PMID:16901643
Biological Process	GO:0060047	heart contraction	ogdha	IGI	ZFIN:ZDB-MRPHLNO-150226-5,ZFIN:ZDB-MRPHLNO-150226-6	Zfish	PMID:25697682
Biological Process	GO:0060047	heart contraction	ogdhb	IGI	ZFIN:ZDB-MRPHLNO-150226-5,ZFIN:ZDB-MRPHLNO-150226-6	Zfish	PMID:25697682
Biological Process	GO:0021766	hippocampus development	Ogdh	IEP		Mouse	MGI:MGI:3662936|PMID:16901643
Biological Process	GO:0106077	histone succinylation	OGDH	IDA		Human	PMID:29211711
Biological Process	GO:0006734	NADH metabolic process	Ogdh	IDA		Rat	PMID:9712727|RGD:2306877
Biological Process	GO:0061034	olfactory bulb mitral cell layer development	Ogdh	IEP		Mouse	MGI:MGI:3662936|PMID:16901643
Biological Process	GO:0021860	pyramidal neuron development	Ogdh	IEP		Mouse	MGI:MGI:3662936|PMID:16901643
Biological Process	GO:0021756	striatum development	Ogdh	IEP		Mouse	MGI:MGI:3662936|PMID:16901643
Biological Process	GO:0006104	succinyl-CoA metabolic process	OGDH	IDA		Human	PMID:24495017
Biological Process	GO:0006104	succinyl-CoA metabolic process	OGDH	IDA		Human	PMID:29211711
Biological Process	GO:0006104	succinyl-CoA metabolic process	Ogdh	IDA		Rat	PMID:9712727|RGD:2306877
Biological Process	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	Ogdh	IEP		Mouse	MGI:MGI:3662936|PMID:16901643
Biological Process	GO:0021794	thalamus development	Ogdh	IEP		Mouse	MGI:MGI:3662936|PMID:16901643
Biological Process	GO:0006099	tricarboxylic acid cycle	Ogdh	IDA		Rat	PMID:9712727|RGD:2306877

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern