Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OMA1
  • Mouse genes Oma1
  • Rat genes Oma1
  • Zfish genes oma1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Oma1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004222	metalloendopeptidase activity	OMA1	IMP		Human	PMID:20038677
Molecular Function	GO:0004222	metalloendopeptidase activity	OMA1	IDA		Human	PMID:25275009
Molecular Function	GO:0004222	metalloendopeptidase activity	OMA1	IDA		Human	PMID:32132706
Molecular Function	GO:0004222	metalloendopeptidase activity	OMA1	IDA		Human	PMID:32132707
Molecular Function	GO:0004222	metalloendopeptidase activity	Oma1	IDA		Mouse	MGI:MGI:5560823|PMID:24550258
Molecular Function	GO:0004222	metalloendopeptidase activity	Oma1	IDA		Mouse	MGI:MGI:6436376|PMID:24719224
Molecular Function	GO:0004222	metalloendopeptidase activity	Oma1	IMP		Mouse	MGI:MGI:5426110|PMID:22433842
Cellular Component	GO:0005743	mitochondrial inner membrane	OMA1	IDA		Human	PMID:32132707
Cellular Component	GO:0005743	mitochondrial inner membrane	Oma1	IDA		Mouse	MGI:MGI:5560823|PMID:24550258
Cellular Component	GO:0031966	mitochondrial membrane	OMA1	IDA		Human	PMID:20038677
Cellular Component	GO:0005739	mitochondrion	Oma1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Oma1	IDA		Mouse	PMID:20038678
Biological Process	GO:0042407	cristae formation	Oma1	IGI	MGI:MGI:1928277	Mouse	PMID:20038678
Biological Process	GO:0042407	cristae formation	Oma1	IGI	MGI:MGI:1916847	Mouse	PMID:20038678
Biological Process	GO:0002024	diet induced thermogenesis	Oma1	IMP		Mouse	MGI:MGI:5426110|PMID:22433842
Biological Process	GO:0097009	energy homeostasis	Oma1	IMP		Mouse	MGI:MGI:5426110|PMID:22433842
Biological Process	GO:0006006	glucose metabolic process	Oma1	IMP		Mouse	MGI:MGI:5426110|PMID:22433842
Biological Process	GO:0140468	HRI-mediated signaling	OMA1	IDA		Human	PMID:32132706
Biological Process	GO:0140468	HRI-mediated signaling	OMA1	IDA		Human	PMID:32132707
Biological Process	GO:0140467	integrated stress response signaling	OMA1	IDA		Human	PMID:32132706
Biological Process	GO:0140467	integrated stress response signaling	OMA1	IDA		Human	PMID:32132707
Biological Process	GO:0006629	lipid metabolic process	Oma1	IMP		Mouse	MGI:MGI:5426110|PMID:22433842
Biological Process	GO:0034982	mitochondrial protein processing	OMA1	IDA		Human	PMID:25275009
Biological Process	GO:0034982	mitochondrial protein processing	OMA1	IMP		Human	PMID:25605331
Biological Process	GO:0034982	mitochondrial protein processing	Oma1	IDA		Mouse	MGI:MGI:5560823|PMID:24550258
Biological Process	GO:0034982	mitochondrial protein processing	Oma1	IDA		Mouse	MGI:MGI:6436376|PMID:24719224
Biological Process	GO:0034982	mitochondrial protein processing	Oma1	IMP		Mouse	PMID:20038678
Biological Process	GO:0033108	mitochondrial respiratory chain complex assembly	Oma1	IMP		Mouse	MGI:MGI:6217514|PMID:26365306
Biological Process	GO:0033108	mitochondrial respiratory chain complex assembly	oma1	IMP		Zfish	PMID:26365306|ZFIN:ZDB-PUB-150916-18
Biological Process	GO:0007005	mitochondrion organization	Oma1	IGI	MGI:MGI:1928277	Mouse	PMID:20038678
Biological Process	GO:0007005	mitochondrion organization	Oma1	IGI	MGI:MGI:1916847	Mouse	PMID:20038678
Biological Process	GO:0010637	negative regulation of mitochondrial fusion	OMA1	IMP		Human	PMID:20038677
Biological Process	GO:0010637	negative regulation of mitochondrial fusion	Oma1	IMP		Mouse	MGI:MGI:5426110|PMID:22433842
Biological Process	GO:0043065	positive regulation of apoptotic process	OMA1	IDA		Human	PMID:25275009
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Oma1	IMP		Mouse	MGI:MGI:5426110|PMID:22433842
Biological Process	GO:0016540	protein autoprocessing	Oma1	IDA		Mouse	MGI:MGI:6436376|PMID:24719224
Biological Process	GO:0016540	protein autoprocessing	Oma1	IDA		Mouse	MGI:MGI:5560823|PMID:24550258
Biological Process	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	OMA1	IMP		Human	PMID:20038677
Biological Process	GO:1903850	regulation of cristae formation	OMA1	IDA		Human	PMID:25275009
Biological Process	GO:0031638	zymogen activation	Oma1	IDA		Mouse	MGI:MGI:5560823|PMID:24550258
Biological Process	GO:0031638	zymogen activation	Oma1	IDA		Mouse	MGI:MGI:6436376|PMID:24719224

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern