Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ONECUT1
  • Mouse genes Onecut1
  • Rat genes Onecut1
  • Zfish genes onecut1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Onecut1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Onecut1	IDA		Mouse	PMID:22780989
Molecular Function	GO:0003677	DNA binding	Onecut1	IDA		Mouse	PMID:16912278
Molecular Function	GO:0003677	DNA binding	Onecut1	IMP		Rat	PMID:8790352|RGD:729198
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Onecut1	IDA		Rat	PMID:20735474|RGD:8553707
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Onecut1	IDA		Mouse	PMID:10825208
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Onecut1	IDA		Rat	PMID:9593691|RGD:729086
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Onecut1	IDA		Mouse	PMID:11944891
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ONECUT1	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Onecut1	IDA		Mouse	PMID:15548585
Cellular Component	GO:0005634	nucleus	Onecut1	IDA		Mouse	PMID:16472605
Cellular Component	GO:0005634	nucleus	Onecut1	IDA		Rat	PMID:8790352|RGD:729198
Biological Process	GO:0009653	anatomical structure morphogenesis	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:16103213
Biological Process	GO:0030183	B cell differentiation	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:12874218
Biological Process	GO:0045165	cell fate commitment	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:16103213
Biological Process	GO:0016477	cell migration	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:17936262
Biological Process	GO:0060271	cilium assembly	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:16472605
Biological Process	GO:0031018	endocrine pancreas development	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:17400205
Biological Process	GO:0007492	endoderm development	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:10825208
Biological Process	GO:0035883	enteroendocrine cell differentiation	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:10825208
Biological Process	GO:0002064	epithelial cell development	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:16472605
Biological Process	GO:0006006	glucose metabolic process	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:10825208
Biological Process	GO:0006006	glucose metabolic process	Onecut1	IMP		Rat	PMID:8790352|RGD:729198
Biological Process	GO:0035622	intrahepatic bile duct development	onecut1	IGI	ZFIN:ZDB-MRPHLNO-051214-2,ZFIN:ZDB-MRPHLNO-110413-4	Zfish	PMID:21215262
Biological Process	GO:0001889	liver development	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:17936262
Biological Process	GO:0001889	liver development	onecut1	IMP	ZFIN:ZDB-MRPHLNO-051215-2	Zfish	PMID:15385156
Biological Process	GO:0001889	liver development	onecut1	IMP	ZFIN:ZDB-MRPHLNO-051214-2	Zfish	PMID:15385156
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:16103213
Biological Process	GO:0007219	Notch signaling pathway	Onecut1	IDA		Mouse	PMID:25446530
Biological Process	GO:0031016	pancreas development	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:17400205
Biological Process	GO:0031016	pancreas development	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:17400205
Biological Process	GO:0003310	pancreatic A cell differentiation	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:10825208
Biological Process	GO:0003311	pancreatic D cell differentiation	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:10825208
Biological Process	GO:0030335	positive regulation of cell migration	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:17936262
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Onecut1	IDA		Mouse	PMID:17261592
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Onecut1	IDA		Rat	PMID:20735474|RGD:8553707
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Onecut1	IMP		Rat	PMID:9593691|RGD:729086
Biological Process	GO:0001952	regulation of cell-matrix adhesion	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:17936262
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:12874218
Biological Process	GO:0048536	spleen development	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:12874218
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Onecut1	IGI	MGI:MGI:1891408	Mouse	PMID:16103213
Biological Process	GO:0003309	type B pancreatic cell differentiation	Onecut1	IMP	MGI:MGI:2179340	Mouse	PMID:10825208

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern