Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ONECUT2
  • Mouse genes Onecut2
  • Rat genes Onecut2
  • Zfish genes onecut2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Onecut2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ONECUT2	IDA		Human	PMID:11478782
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Onecut2	IDA		Mouse	PMID:17400205
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ONECUT2	IDA		Human	PMID:11478782
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Onecut2	IDA		Mouse	PMID:11944891
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ONECUT2	IDA		Human	PMID:28473536
Cellular Component	GO:0015629	actin cytoskeleton	ONECUT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ONECUT2	IDA		Human	GO_REF:0000052
Biological Process	GO:0009653	anatomical structure morphogenesis	Onecut2	IMP	MGI:MGI:3588425	Mouse	PMID:16103213
Biological Process	GO:0045165	cell fate commitment	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:16103213
Biological Process	GO:0016477	cell migration	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:17936262
Biological Process	GO:0060271	cilium assembly	Onecut2	IMP	MGI:MGI:3588425	Mouse	PMID:16472605
Biological Process	GO:0031018	endocrine pancreas development	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:17400205
Biological Process	GO:0002064	epithelial cell development	Onecut2	IMP	MGI:MGI:3588425	Mouse	PMID:16472605
Biological Process	GO:0001889	liver development	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:17936262
Biological Process	GO:1905319	mesenchymal stem cell migration	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:17936262
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:16103213
Biological Process	GO:0031016	pancreas development	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:17400205
Biological Process	GO:0048935	peripheral nervous system neuron development	Onecut2	IMP	MGI:MGI:3588425	Mouse	PMID:17698011
Biological Process	GO:1905322	positive regulation of mesenchymal stem cell migration	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:17936262
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ONECUT2	IDA		Human	PMID:11478782
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Onecut2	IDA		Mouse	PMID:17400205
Biological Process	GO:0001952	regulation of cell-matrix adhesion	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:17936262
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Onecut2	IGI	MGI:MGI:1196423	Mouse	PMID:16103213

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern