Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OPN4
  • Mouse genes Opn4
  • Rat genes Opn4
  • Zfish genes opn4.1,opn4a,opn4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Opn4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005502	11-cis retinal binding	OPN4	IDA		Human	PMID:15674244
Molecular Function	GO:0008020	G protein-coupled photoreceptor activity	OPN4	IDA		Human	PMID:15674244
Molecular Function	GO:0008020	G protein-coupled photoreceptor activity	Opn4	IMP		Mouse	MGI:MGI:2667269|PMID:12808468
Molecular Function	GO:0008020	G protein-coupled photoreceptor activity	Opn4	IDA		Rat	PMID:11834834|RGD:633348
Molecular Function	GO:0009881	photoreceptor activity	opn4.1	IDA		Zfish	PMID:21966429
Molecular Function	GO:0009881	photoreceptor activity	opn4.1	IDA		Zfish	PMID:21833582
Molecular Function	GO:0009881	photoreceptor activity	opn4a	IDA		Zfish	PMID:21833582
Molecular Function	GO:0009881	photoreceptor activity	opn4b	IDA		Zfish	PMID:21833582
Molecular Function	GO:0005515	protein binding	OPN4	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Cellular Component	GO:0005886	plasma membrane	OPN4	IDA		Human	PMID:31380578
Cellular Component	GO:0005886	plasma membrane	OPN4	IDA		Human	PMID:31730232
Cellular Component	GO:1990913	sperm head plasma membrane	Opn4	IDA		Mouse	PMID:31924821
Biological Process	GO:0050960	detection of temperature stimulus involved in thermoception	Opn4	IGI	MGI:MGI:97914	Mouse	PMID:31924821
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	opn4.1	IDA		Zfish	PMID:24678795
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	opn4a	IDA		Zfish	PMID:24678795
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	opn4b	IDA		Zfish	PMID:24678795
Biological Process	GO:1990384	hyaloid vascular plexus regression	Opn4	IMP		Mouse	MGI:MGI:6359287|PMID:30936473
Biological Process	GO:0008377	light-induced release of internally sequestered calcium ion	opn4.1	IDA		Zfish	PMID:21966429
Biological Process	GO:0007634	optokinetic behavior	Opn4	IMP		Mouse	MGI:MGI:5699646|PMID:26392540
Biological Process	GO:0007602	phototransduction	OPN4	IDA		Human	PMID:15674244
Biological Process	GO:0007602	phototransduction	Opn4	IMP		Mouse	MGI:MGI:2667269|PMID:12808468
Biological Process	GO:0007602	phototransduction	Opn4	IDA		Rat	PMID:11834834|RGD:633348
Biological Process	GO:0042752	regulation of circadian rhythm	Opn4	IMP		Mouse	MGI:MGI:2667269|PMID:12808468
Biological Process	GO:0043052	thermotaxis	Opn4	IGI	MGI:MGI:97914	Mouse	PMID:31924821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern