Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ORC1
  • Mouse genes Orc1
  • Rat genes Orc1
  • Zfish genes orc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Orc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Orc1	IDA		Rat	PMID:16982680|RGD:2313416
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q13309	Human	PMID:11931757
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q13416	Human	PMID:11931757
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:O43913	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q13416	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q9UBD5	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:O43913	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q13416	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q9UBD5	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q15554	Human	PMID:16799465
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:O43913	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q13416	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q9UBD5	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:P03211	Human	PMID:18946490
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:O43913	Human	PMID:22398447
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q13416	Human	PMID:22398447
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q9UBD5	Human	PMID:22398447
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:O43913	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:Q13416	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ORC1	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Cellular Component	GO:0000781	chromosome, telomeric region	ORC1	IDA		Human	PMID:24270157
Cellular Component	GO:0000781	chromosome, telomeric region	ORC1	HDA		Human	PMID:19135898
Cellular Component	GO:0005664	nuclear origin of replication recognition complex	ORC1	IDA		Human	PMID:20932478
Cellular Component	GO:0005664	nuclear origin of replication recognition complex	ORC1	IDA		Human	PMID:21029866
Cellular Component	GO:0005654	nucleoplasm	ORC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Orc1	IDA		Rat	PMID:16982680|RGD:2313416
Cellular Component	GO:0000808	origin recognition complex	ORC1	IDA		Human	PMID:17716973
Biological Process	GO:0043009	chordate embryonic development	orc1	IMP	ZFIN:ZDB-MRPHLNO-120424-1	Zfish	PMID:21358633
Biological Process	GO:0043009	chordate embryonic development	orc1	IMP	ZFIN:ZDB-MRPHLNO-120424-2,ZFIN:ZDB-MRPHLNO-120426-1	Zfish	PMID:21358633
Biological Process	GO:0060271	cilium assembly	orc1	IMP	ZFIN:ZDB-MRPHLNO-120424-1	Zfish	PMID:30696958
Biological Process	GO:0070318	positive regulation of G0 to G1 transition	Orc1	IMP		Rat	PMID:18499104|RGD:9588277
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Orc1	IMP		Rat	PMID:18499104|RGD:9588277
Biological Process	GO:0040014	regulation of multicellular organism growth	orc1	IMP	ZFIN:ZDB-MRPHLNO-120424-1	Zfish	PMID:22398447
Biological Process	GO:0001878	response to yeast	orc1	IDA		Zfish	PMID:23947337

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern