Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ORC2
  • Mouse genes Orc2
  • Rat genes Orc2
  • Zfish genes orc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Orc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003688	DNA replication origin binding	Orc2	IDA		Mouse	PMID:12941272
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q7L590	Human	PMID:11095689
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q13415	Human	PMID:11931757
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:P25205	Human	PMID:12364596
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43913	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43929	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q13415	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q7L590	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q99459	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43913	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43929	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q13415	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q9UBD5	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:P03211	Human	PMID:16799465
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q15554	Human	PMID:16799465
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43913	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43929	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q13415	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q9UBD5	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:P03211	Human	PMID:18946490
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q99459	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q9UFC0	Human	PMID:20932478
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:P83916	Human	PMID:21383955
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q13415	Human	PMID:22398447
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q08050	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43913	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q13415	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:O43929	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:P57055	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q9NS91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORC2	IPI	UniProtKB:Q9UI47-2	Human	PMID:32296183
Cellular Component	GO:0005813	centrosome	ORC2	IDA		Human	PMID:15215892
Cellular Component	GO:0000785	chromatin	Orc2	IDA		Mouse	PMID:15983387
Cellular Component	GO:0000781	chromosome, telomeric region	ORC2	IDA		Human	PMID:24270157
Cellular Component	GO:0000781	chromosome, telomeric region	ORC2	HDA		Human	PMID:19135898
Cellular Component	GO:0000792	heterochromatin	ORC2	IDA		Human	PMID:15215892
Cellular Component	GO:0000792	heterochromatin	Orc2	IDA		Mouse	PMID:15998811
Cellular Component	GO:0000939	inner kinetochore	Orc2	IDA		Mouse	PMID:14519686
Cellular Component	GO:0016020	membrane	ORC2	HDA		Human	PMID:19946888
Cellular Component	GO:0005664	nuclear origin of replication recognition complex	ORC2	IDA		Human	PMID:20932478
Cellular Component	GO:0005664	nuclear origin of replication recognition complex	ORC2	IDA		Human	PMID:21029866
Cellular Component	GO:0005664	nuclear origin of replication recognition complex	Orc2	IDA		Mouse	PMID:12941272
Cellular Component	GO:0005654	nucleoplasm	ORC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ORC2	IDA		Human	PMID:21383955
Cellular Component	GO:0000808	origin recognition complex	ORC2	IDA		Human	PMID:17716973

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern