Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ORMDL1
  • Mouse genes Ormdl1
  • Rat genes Ormdl1
  • Zfish genes ormdl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ormdl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:A6NKB5-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:O00559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:O75208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:P07307-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q3ZAQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q4KMG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q53FP2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q5T4F4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q8NBQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q96AN5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q96MV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q99942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q9NYG8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ORMDL1	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	ORMDL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ORMDL1	IDA		Human	PMID:12093374
Biological Process	GO:0006672	ceramide metabolic process	ORMDL1	IMP		Human	PMID:20182505
Biological Process	GO:0061744	motor behavior	Ormdl1	IGI	MGI:MGI:1913862	Mouse	PMID:31880535
Biological Process	GO:0042552	myelination	Ormdl1	IGI	MGI:MGI:1913862	Mouse	PMID:31880535
Biological Process	GO:1900060	negative regulation of ceramide biosynthetic process	ORMDL1	IMP		Human	PMID:25691431
Biological Process	GO:2000303	regulation of ceramide biosynthetic process	Ormdl1	IGI	MGI:MGI:1913862	Mouse	PMID:31880535
Biological Process	GO:0090153	regulation of sphingolipid biosynthetic process	Ormdl1	IGI	MGI:MGI:1913862	Mouse	PMID:31880535
Biological Process	GO:0006686	sphingomyelin biosynthetic process	Ormdl1	IGI	MGI:MGI:1913862	Mouse	PMID:31880535

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern