Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Osr1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes OSR1
- Mouse genes Osr1
- Rat genes Osr1
- Zfish genes osr1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Osr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Osr1	IPI	UniProtKB:Q62232	Mouse	MGI:MGI:5563874\|PMID:24598167
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	OSR1	IDA		Human	PMID:28473536
Cellular Component	GO:0005938	cell cortex	Osr1	IDA		Rat	PMID:25515571\|RGD:11535087
Cellular Component	GO:0005829	cytosol	Osr1	IDA		Rat	PMID:25515571\|RGD:11535087
Cellular Component	GO:0005634	nucleus	OSR1	IDA		Human	GO_REF:0000054
Biological Process	GO:0035779	angioblast cell differentiation	osr1	IMP		Zfish	PMID:18787069\|ZFIN:ZDB-PUB-080915-23
Biological Process	GO:0030154	cell differentiation	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0072111	cell proliferation involved in kidney development	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0071300	cellular response to retinoic acid	Osr1	IEP		Mouse	MGI:MGI:5009359\|PMID:20171952
Biological Process	GO:0002062	chondrocyte differentiation	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0042733	embryonic digit morphogenesis	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0072498	embryonic skeletal joint development	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0036023	embryonic skeletal limb joint morphogenesis	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0008406	gonad development	Osr1	IMP	MGI:MGI:3613748	Mouse	PMID:16223478
Biological Process	GO:0007507	heart development	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0007507	heart development	Osr1	IMP	MGI:MGI:3613748	Mouse	PMID:16223478
Biological Process	GO:0048389	intermediate mesoderm development	Osr1	IMP	MGI:MGI:3613748	Mouse	PMID:16223478
Biological Process	GO:0048389	intermediate mesoderm development	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-2	Zfish	PMID:18787069
Biological Process	GO:0001822	kidney development	osr1	IDA		Zfish	PMID:17011543
Biological Process	GO:0001822	kidney development	osr1	IMP	ZFIN:ZDB-MRPHLNO-070321-3	Zfish	PMID:17011543
Biological Process	GO:0072143	mesangial cell development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0048382	mesendoderm development	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-2	Zfish	PMID:18787069
Biological Process	GO:0072180	mesonephric duct morphogenesis	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0001823	mesonephros development	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0072207	metanephric epithelium development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0072239	metanephric glomerulus vasculature development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0072259	metanephric interstitial fibroblast development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0072162	metanephric mesenchymal cell differentiation	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0072075	metanephric mesenchyme development	Osr1	IDA		Mouse	MGI:MGI:5009359\|PMID:20171952
Biological Process	GO:0072133	metanephric mesenchyme morphogenesis	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0072234	metanephric nephron tubule development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0072208	metanephric smooth muscle tissue development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0001656	metanephros development	Osr1	IMP	MGI:MGI:3613748	Mouse	PMID:16223478
Biological Process	GO:0042474	middle ear morphogenesis	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:3848564\|PMID:19389375
Biological Process	GO:0043066	negative regulation of apoptotic process	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:1905408	negative regulation of creatine transmembrane transporter activity	OSR1	IDA		Human	PMID:25531585
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	osr1	IMP		Zfish	PMID:17011543\|ZFIN:ZDB-PUB-061020-6
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	osr1	IMP		Zfish	PMID:18787069\|ZFIN:ZDB-PUB-080915-23
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:2000650	negative regulation of sodium ion transmembrane transporter activity	OSR1	IDA		Human	PMID:25531585
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	osr1	IMP		Zfish	PMID:17011543\|ZFIN:ZDB-PUB-061020-6
Biological Process	GO:0042476	odontogenesis	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:3848564\|PMID:19389375
Biological Process	GO:0072268	pattern specification involved in metanephros development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0033339	pectoral fin development	osr1	IMP	ZFIN:ZDB-MRPHLNO-070321-3	Zfish	PMID:22129829
Biological Process	GO:0033339	pectoral fin development	osr1	IGI	ZFIN:ZDB-MRPHLNO-090121-1,ZFIN:ZDB-MRPHLNO-120127-7	Zfish	PMID:22129829
Biological Process	GO:0033339	pectoral fin development	osr1	IGI	ZFIN:ZDB-MRPHLNO-070321-3,ZFIN:ZDB-MRPHLNO-070321-4	Zfish	PMID:22129829
Biological Process	GO:0033339	pectoral fin development	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-1	Zfish	PMID:22129829
Biological Process	GO:0072112	podocyte differentiation	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-1	Zfish	PMID:24722440
Biological Process	GO:0030501	positive regulation of bone mineralization	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:3848564\|PMID:19389375
Biological Process	GO:2000543	positive regulation of gastrulation	OSR1	IMP		Human	PMID:21281489
Biological Process	GO:0010628	positive regulation of gene expression	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:4950000\|PMID:21262216
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Osr1	IDA		Mouse	MGI:MGI:3818159\|PMID:17547533
Biological Process	GO:0072166	posterior mesonephric tubule development	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0035777	pronephric distal tubule development	osr1	IMP		Zfish	PMID:18787069\|ZFIN:ZDB-PUB-080915-23
Biological Process	GO:0035775	pronephric glomerulus morphogenesis	osr1	IMP		Zfish	PMID:18787069\|ZFIN:ZDB-PUB-080915-23
Biological Process	GO:0035775	pronephric glomerulus morphogenesis	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-1	Zfish	PMID:24722440
Biological Process	GO:0035778	pronephric nephron tubule epithelial cell differentiation	osr1	IMP		Zfish	PMID:18787069\|ZFIN:ZDB-PUB-080915-23
Biological Process	GO:0035776	pronephric proximal tubule development	osr1	IMP		Zfish	PMID:18787069\|ZFIN:ZDB-PUB-080915-23
Biological Process	GO:0035776	pronephric proximal tubule development	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-1	Zfish	PMID:24722440
Biological Process	GO:0048793	pronephros development	OSR1	IMP		Human	PMID:21281489
Biological Process	GO:0048793	pronephros development	osr1	IDA		Zfish	PMID:17011543
Biological Process	GO:0048793	pronephros development	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-2	Zfish	PMID:18787069
Biological Process	GO:1903224	regulation of endodermal cell differentiation	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-1	Zfish	PMID:25233796
Biological Process	GO:1900107	regulation of nodal signaling pathway	osr1	IMP	ZFIN:ZDB-MRPHLNO-090121-1	Zfish	PMID:25233796
Biological Process	GO:0072184	renal vesicle progenitor cell differentiation	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0060021	roof of mouth development	Osr1	IGI	UniProtKB:Q91ZD1	Mouse	MGI:MGI:3848564\|PMID:19389375
Biological Process	GO:0035725	sodium ion transmembrane transport	Osr1	IMP		Mouse	PMID:31736353
Biological Process	GO:0072168	specification of anterior mesonephric tubule identity	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0072169	specification of posterior mesonephric tubule identity	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0048863	stem cell differentiation	Osr1	IDA		Mouse	MGI:MGI:5009359\|PMID:20171952
Biological Process	GO:0072190	ureter urothelium development	Osr1	IMP		Mouse	MGI:MGI:3826342\|PMID:18835385
Biological Process	GO:0001657	ureteric bud development	Osr1	IMP		Mouse	MGI:MGI:3697513\|PMID:16790474
Biological Process	GO:0001655	urogenital system development	Osr1	IMP		Mouse	MGI:MGI:3613210\|PMID:16223478

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.