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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Otub1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Otub1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0004843cysteine-type deubiquitinase activityOTUB1IDAHumanPMID:18954305
Molecular FunctionGO:0004843cysteine-type deubiquitinase activityOTUB1IDAHumanPMID:19211026
Molecular FunctionGO:0004843cysteine-type deubiquitinase activityOTUB1IDAHumanPMID:23827681
Molecular FunctionGO:0019784deNEDDylase activityOTUB1IDAHumanPMID:18954305
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9RI12HumanPMID:16364312
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P35637HumanPMID:18954305
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P63244HumanPMID:18954305
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P51668HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P51965HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P61077HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P62837HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P62837HumanPMID:19615732
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q56921HumanPMID:20553488
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P02766HumanPMID:21900206
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P04637HumanPMID:22124327
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P51668HumanPMID:22124327
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P61077HumanPMID:22124327
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P62837HumanPMID:22124327
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q00987HumanPMID:22124327
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q13490HumanPMID:23524849
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P61077HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9Y2X8HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P22314HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P51668HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P51965HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P61077HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P62837HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q13148HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q969T4HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q96LR5HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q99497HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9NWT6HumanPMID:26752685
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P62837HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q969T4HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q96LR5HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9NWT6HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9Y2X8HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P51668HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P61077HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P62837HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q969T4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q96LR5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9Y2X8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:G5E9A7HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O14645HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O14773HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O14901HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O43464HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O60260-5HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O60333-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O75190-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:O76024HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P00441HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P01023HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P02766HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P04792HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P05067HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P07686HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P0CG47HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P14136HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P19404HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P22314HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P28799HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P35240-4HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P35637HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P37840HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P40337-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P46379-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P49768-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P50570-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P51608HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P54253HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:P60891HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q13148HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q14203-5HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q53GS7HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q7Z699HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q86WV8HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q8WUW1HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q8WXH2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q99497HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9UMF0HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q9Y3C5HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingOTUB1IPIUniProtKB:Q8N6M0HumanPMID:33421002
Molecular FunctionGO:0043130ubiquitin bindingOTUB1IDAHumanPMID:19211026
Molecular FunctionGO:0031625ubiquitin protein ligase bindingOTUB1IPIUniProtKB:P61088HumanPMID:20725033
Cellular ComponentGO:0005737cytoplasmOtub1IDARatPMID:22279542|RGD:7175260
Cellular ComponentGO:0070062extracellular exosomeOTUB1HDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular exosomeOTUB1HDAHumanPMID:23533145
Cellular ComponentGO:0005634nucleusOtub1IDARatPMID:22279542|RGD:7175260
Biological ProcessGO:0071347cellular response to interleukin-1Otub1IEPRatPMID:22279542|RGD:7175260
Biological ProcessGO:0006974DNA damage responseOTUB1IDAHumanPMID:20725033
Biological ProcessGO:2000780negative regulation of double-strand break repairOTUB1IMPHumanPMID:20725033
Biological ProcessGO:1901315negative regulation of histone H2A K63-linked ubiquitinationOTUB1IDAHumanPMID:20725033
Biological ProcessGO:0071108protein K48-linked deubiquitinationOTUB1IDAHumanPMID:18954305
Biological ProcessGO:0071108protein K48-linked deubiquitinationOTUB1IDAHumanPMID:19211026
Biological ProcessGO:0071108protein K48-linked deubiquitinationOTUB1IDAHumanPMID:23827681

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory