Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OTUD4
  • Mouse genes Otud4
  • Rat genes Otud4
  • Zfish genes otud4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Otud4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	OTUD4	IDA		Human	PMID:23827681
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	OTUD4	IDA		Human	PMID:29395066
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	Otud4	IDA		Mouse	MGI:MGI:6120140|PMID:29395066
Molecular Function	GO:0060090	molecular adaptor activity	OTUD4	IDA		Human	PMID:25944111
Molecular Function	GO:0005515	protein binding	OTUD4	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OTUD4	IPI	UniProtKB:P42224	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OTUD4	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OTUD4	IPI	UniProtKB:Q96B26	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OTUD4	IPI	UniProtKB:P11473-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD4	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD4	IPI	UniProtKB:Q96B26	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	OTUD4	HDA		Human	PMID:22681889
Cellular Component	GO:0005829	cytosol	OTUD4	IDA		Human	GO_REF:0000052
Biological Process	GO:0043010	camera-type eye development	otud4	IMP	ZFIN:ZDB-MRPHLNO-140306-2	Zfish	PMID:23656588
Biological Process	GO:0043010	camera-type eye development	otud4	IGI	ZFIN:ZDB-MRPHLNO-140306-1,ZFIN:ZDB-MRPHLNO-140306-2	Zfish	PMID:23656588
Biological Process	GO:0021549	cerebellum development	otud4	IGI	ZFIN:ZDB-MRPHLNO-140306-1,ZFIN:ZDB-MRPHLNO-140306-2	Zfish	PMID:23656588
Biological Process	GO:0021549	cerebellum development	otud4	IMP	ZFIN:ZDB-MRPHLNO-140306-2	Zfish	PMID:23656588
Biological Process	GO:0009953	dorsal/ventral pattern formation	otud4	IGI	ZFIN:ZDB-MRPHLNO-100225-21,ZFIN:ZDB-MRPHLNO-130916-1	Zfish	PMID:23665588
Biological Process	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	OTUD4	IDA		Human	PMID:29395066
Biological Process	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	Otud4	IDA		Mouse	MGI:MGI:6120140|PMID:29395066
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	OTUD4	IDA		Human	PMID:29395066
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	Otud4	IDA		Mouse	MGI:MGI:6120140|PMID:29395066
Biological Process	GO:1901537	positive regulation of DNA demethylation	OTUD4	IDA		Human	PMID:25944111
Biological Process	GO:0071108	protein K48-linked deubiquitination	OTUD4	IDA		Human	PMID:23827681
Biological Process	GO:0070536	protein K63-linked deubiquitination	OTUD4	IDA		Human	PMID:29395066
Biological Process	GO:0070536	protein K63-linked deubiquitination	Otud4	IDA		Mouse	MGI:MGI:6120140|PMID:29395066
Biological Process	GO:1903093	regulation of protein K48-linked deubiquitination	OTUD4	IDA		Human	PMID:25944111

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern