Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OTUD7B
  • Mouse genes Otud7b
  • Rat genes Otud7b
  • Zfish genes otud7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Otud7b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	OTUD7B	IDA		Human	PMID:23827681
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Otud7b	IMP		Mouse	MGI:MGI:5474156|PMID:23334419
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Otud7b	IDA		Mouse	PMID:12682062
Molecular Function	GO:0008234	cysteine-type peptidase activity	Otud7b	IMP		Mouse	MGI:MGI:5474156|PMID:23334419
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	OTUD7B	IDA		Human	PMID:21097510
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	Otud7b	IDA		Mouse	MGI:MGI:5447608|PMID:18281465
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q9Y4K3	Human	PMID:11463333
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q8IVM0	Human	PMID:18029035
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q99497	Human	PMID:21097510
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q92569	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q7L775	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q7Z5V6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q8N0X7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q96BN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q96LI6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:Q9H305	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OTUD7B	IPI	UniProtKB:P46934	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Otud7b	IPI	UniProtKB:Q99497	Mouse	MGI:MGI:5574296|PMID:21097510
Molecular Function	GO:0005515	protein binding	Otud7b	IPI	UniProtKB:Q60803	Mouse	MGI:MGI:5474156|PMID:23334419
Molecular Function	GO:0005515	protein binding	Otud7b	IPI	UniProtKB:Q61315	Mouse	MGI:MGI:5447608|PMID:18281465
Molecular Function	GO:0005515	protein binding	Otud7b	IPI	UniProtKB:P25942	Mouse	MGI:MGI:5474156|PMID:23334419
Cellular Component	GO:0005737	cytoplasm	OTUD7B	IDA		Human	PMID:11463333
Cellular Component	GO:0005737	cytoplasm	Otud7b	IDA		Mouse	PMID:12682062
Cellular Component	GO:0005634	nucleus	OTUD7B	IDA		Human	PMID:11463333
Biological Process	GO:0001701	in utero embryonic development	Otud7b	IMP	MGI:MGI:5637162	Mouse	PMID:27996060
Biological Process	GO:0002385	mucosal immune response	Otud7b	IMP		Mouse	MGI:MGI:5474156|PMID:23334419
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	OTUD7B	IDA		Human	PMID:11463333
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	Otud7b	IMP		Mouse	MGI:MGI:5474156|PMID:23334419
Biological Process	GO:0032717	negative regulation of interleukin-8 production	OTUD7B	IDA		Human	PMID:21097510
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	OTUD7B	IDA		Human	PMID:21097510
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	OTUD7B	IDA		Human	PMID:21097510
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Otud7b	IDA		Mouse	MGI:MGI:5574296|PMID:21097510
Biological Process	GO:0007219	Notch signaling pathway	otud7b	IMP	ZFIN:ZDB-MRPHLNO-100225-19	Zfish	PMID:20040115
Biological Process	GO:0016579	protein deubiquitination	Otud7b	IDA		Mouse	PMID:12682062
Biological Process	GO:0035871	protein K11-linked deubiquitination	OTUD7B	IDA		Human	PMID:20622874
Biological Process	GO:0035871	protein K11-linked deubiquitination	OTUD7B	IDA		Human	PMID:23827681
Biological Process	GO:0071108	protein K48-linked deubiquitination	OTUD7B	IDA		Human	PMID:21097510
Biological Process	GO:0071108	protein K48-linked deubiquitination	Otud7b	IMP		Mouse	MGI:MGI:5474156|PMID:23334419
Biological Process	GO:0070536	protein K63-linked deubiquitination	OTUD7B	IDA		Human	PMID:20622874

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern