Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OVOL1
  • Mouse genes Ovol1
  • Rat genes Ovol1
  • Zfish genes ovol1a,ovol1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ovol1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Ovol1	IDA		Mouse	MGI:MGI:3710912|PMID:17311813
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Ovol1	IMP		Mouse	MGI:MGI:3710912|PMID:17311813
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Ovol1	IDA		Mouse	PMID:17049212
Molecular Function	GO:0005515	protein binding	OVOL1	IPI	UniProtKB:Q03252	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OVOL1	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Ovol1	IDA		Mouse	MGI:MGI:3710912|PMID:17311813
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	OVOL1	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Ovol1	IDA		Mouse	PMID:9808631
Cellular Component	GO:0005634	nucleus	ovol1a	IDA		Zfish	PMID:20463035
Biological Process	GO:0008544	epidermis development	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:9808631
Biological Process	GO:0008544	epidermis development	Ovol1	IGI	MGI:MGI:1338039	Mouse	PMID:24735878
Biological Process	GO:0090150	establishment of protein localization to membrane	ovol1a	IMP	ZFIN:ZDB-MRPHLNO-100622-4	Zfish	PMID:20463035
Biological Process	GO:0051729	germline cell cycle switching, mitotic to meiotic cell cycle	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:15716349
Biological Process	GO:0043616	keratinocyte proliferation	Ovol1	IGI	MGI:MGI:1338039	Mouse	PMID:24735878
Biological Process	GO:0001822	kidney development	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:17049212
Biological Process	GO:0044771	meiotic cell cycle phase transition	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:15716349
Biological Process	GO:0007498	mesoderm development	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:9808631
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Ovol1	IGI	MGI:MGI:1338039	Mouse	PMID:24735878
Biological Process	GO:1901994	negative regulation of meiotic cell cycle phase transition	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:15716349
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Ovol1	IGI	MGI:MGI:1338039	Mouse	PMID:24735878
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ovol1	IMP		Mouse	MGI:MGI:3710912|PMID:17311813
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ovol1	IDA		Mouse	PMID:15716349
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ovol1	IDA		Mouse	PMID:17049212
Biological Process	GO:0001755	neural crest cell migration	ovol1a	IMP	ZFIN:ZDB-MRPHLNO-100622-4	Zfish	PMID:20463035
Biological Process	GO:0001755	neural crest cell migration	ovol1a	IGI	ZFIN:ZDB-GENO-100728-4,ZFIN:ZDB-MRPHLNO-100622-4	Zfish	PMID:20463035
Biological Process	GO:0070285	pigment cell development	ovol1a	IGI	ZFIN:ZDB-GENO-100728-4,ZFIN:ZDB-MRPHLNO-100622-4	Zfish	PMID:20463035
Biological Process	GO:0070285	pigment cell development	ovol1a	IMP	ZFIN:ZDB-MRPHLNO-100622-4	Zfish	PMID:20463035
Biological Process	GO:0043588	skin development	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:17049212
Biological Process	GO:0007283	spermatogenesis	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:15716349
Biological Process	GO:0007283	spermatogenesis	Ovol1	IMP	MGI:MGI:1926599	Mouse	PMID:9808631
Biological Process	GO:0072089	stem cell proliferation	Ovol1	IGI	MGI:MGI:1338039	Mouse	PMID:24735878

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern