Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OXT
  • Mouse genes Oxt
  • Rat genes Oxt
  • Zfish genes oxt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Oxt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005184	neuropeptide hormone activity	Oxt	IDA		Rat	PMID:19560475|RGD:2312653
Molecular Function	GO:0031855	oxytocin receptor binding	Oxt	IDA		Rat	PMID:15821089|RGD:1579892
Molecular Function	GO:0031855	oxytocin receptor binding	Oxt	IDA		Rat	PMID:19560475|RGD:2312653
Molecular Function	GO:0005515	protein binding	OXT	IPI	UniProtKB:Q9UHG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Oxt	IPI	RGD:3671	Rat	PMID:15927785|RGD:1625246
Cellular Component	GO:0005737	cytoplasm	Oxt	IDA		Mouse	PMID:12383972
Cellular Component	GO:0005737	cytoplasm	Oxt	IDA		Rat	PMID:19017254|RGD:2303960
Cellular Component	GO:0005576	extracellular region	Oxt	IDA		Mouse	PMID:12907752
Cellular Component	GO:0005615	extracellular space	Oxt	IDA		Rat	PMID:18953097|RGD:2303963
Cellular Component	GO:0030141	secretory granule	Oxt	IDA		Rat	PMID:11456414|RGD:2304235
Cellular Component	GO:0043195	terminal bouton	Oxt	IDA		Rat	PMID:18987209|RGD:2303962
Biological Process	GO:0042756	drinking behavior	Oxt	IDA		Rat	PMID:15380376|RGD:2304179
Biological Process	GO:0042755	eating behavior	Oxt	IDA		Rat	PMID:15380376|RGD:2304179
Biological Process	GO:0007565	female pregnancy	Oxt	IEP		Rat	PMID:18936075|RGD:2303964
Biological Process	GO:0007625	grooming behavior	Oxt	IDA		Rat	PMID:17505467|RGD:2304137
Biological Process	GO:0007507	heart development	Oxt	IEP		Rat	PMID:15316117|RGD:2304180
Biological Process	GO:0042538	hyperosmotic salinity response	Oxt	IEP		Rat	PMID:18088359|RGD:2304116
Biological Process	GO:0060179	male mating behavior	Oxt	IEP		Rat	PMID:18655888|RGD:2304091
Biological Process	GO:0002125	maternal aggressive behavior	Oxt	IEP		Rat	PMID:18655888|RGD:2304091
Biological Process	GO:0042711	maternal behavior	Oxt	IDA		Rat	PMID:18513132|RGD:2304107
Biological Process	GO:0007613	memory	Oxt	IEP		Rat	PMID:18304743|RGD:2304112
Biological Process	GO:0050801	monoatomic ion homeostasis	oxt	IMP	ZFIN:ZDB-MRPHLNO-110802-5	Zfish	PMID:21104292
Biological Process	GO:0045776	negative regulation of blood pressure	Oxt	IMP		Rat	PMID:18562099|RGD:2304105
Biological Process	GO:0060455	negative regulation of gastric acid secretion	Oxt	IDA		Rat	PMID:11764003|RGD:2304192
Biological Process	GO:0035811	negative regulation of urine volume	Oxt	IDA		Rat	PMID:18057218|RGD:2304118
Biological Process	GO:0045777	positive regulation of blood pressure	Oxt	IDA		Rat	PMID:19120122|RGD:2303957
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Oxt	IMP		Mouse	MGI:MGI:6162300|PMID:18071238
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Oxt	IDA		Rat	PMID:10497238|RGD:2304226
Biological Process	GO:0045925	positive regulation of female receptivity	Oxt	IDA		Rat	PMID:11264328|RGD:2304217
Biological Process	GO:0060450	positive regulation of hindgut contraction	Oxt	IDA		Rat	PMID:19258489|RGD:2304084
Biological Process	GO:0010701	positive regulation of norepinephrine secretion	Oxt	IDA		Rat	PMID:14656297|RGD:2304181
Biological Process	GO:0045778	positive regulation of ossification	Oxt	IDA		Rat	PMID:18257653|RGD:2304114
Biological Process	GO:0060406	positive regulation of penile erection	Oxt	IDA		Rat	PMID:18671741|RGD:2304089
Biological Process	GO:0032308	positive regulation of prostaglandin secretion	Oxt	IDA		Rat	PMID:9575824|RGD:2304227
Biological Process	GO:0035815	positive regulation of renal sodium excretion	Oxt	IDA		Rat	PMID:17559853|RGD:2304131
Biological Process	GO:0051965	positive regulation of synapse assembly	Oxt	IDA		Rat	PMID:16488155|RGD:2304173
Biological Process	GO:0050806	positive regulation of synaptic transmission	Oxt	IDA		Rat	PMID:17314286|RGD:2304169
Biological Process	GO:0070474	positive regulation of uterine smooth muscle contraction	Oxt	IDA		Rat	PMID:19164477|RGD:2303954
Biological Process	GO:0044058	regulation of digestive system process	Oxt	IDA		Rat	PMID:12690433|RGD:2304324
Biological Process	GO:0002027	regulation of heart rate	Oxt	IDA		Rat	PMID:3668162|RGD:2304216
Biological Process	GO:0051930	regulation of sensory perception of pain	Oxt	IDA		Rat	PMID:17664006|RGD:2304129
Biological Process	GO:0014823	response to activity	Oxt	IEP		Rat	PMID:16157794|RGD:2304174
Biological Process	GO:0001975	response to amphetamine	Oxt	IEP		Rat	PMID:17383105|RGD:2304140
Biological Process	GO:0051591	response to cAMP	Oxt	IEP		Rat	PMID:11168841|RGD:2304218
Biological Process	GO:0042220	response to cocaine	Oxt	IEP		Rat	PMID:18609307|RGD:2304103
Biological Process	GO:0051602	response to electrical stimulus	Oxt	IEP		Rat	PMID:18823708|RGD:2303968
Biological Process	GO:0032355	response to estradiol	Oxt	IEP		Rat	PMID:19258489|RGD:2304084
Biological Process	GO:0045472	response to ether	Oxt	IEP		Rat	PMID:1943445|RGD:2304237
Biological Process	GO:0032094	response to food	Oxt	IEP		Rat	PMID:18832082|RGD:2303967
Biological Process	GO:0051384	response to glucocorticoid	Oxt	IEP		Rat	PMID:17553493|RGD:2304133
Biological Process	GO:0014070	response to organic cyclic compound	Oxt	IEP		Rat	PMID:12504828|RGD:2304189
Biological Process	GO:0014070	response to organic cyclic compound	Oxt	IDA		Rat	PMID:19248249|RGD:2304085
Biological Process	GO:0043434	response to peptide hormone	Oxt	IEP		Rat	PMID:19246538|RGD:2304086
Biological Process	GO:0032570	response to progesterone	Oxt	IDA		Rat	PMID:17280592|RGD:2304170
Biological Process	GO:0034695	response to prostaglandin E	Oxt	IEP		Rat	PMID:19017254|RGD:2303960
Biological Process	GO:0032526	response to retinoic acid	Oxt	IEP		Rat	PMID:15316117|RGD:2304180
Biological Process	GO:0048545	response to steroid hormone	Oxt	IEP		Rat	PMID:12588901|RGD:2304187
Biological Process	GO:0009744	response to sucrose	Oxt	IEP		Rat	PMID:19022308|RGD:2303959
Biological Process	GO:0030431	sleep	Oxt	IDA		Rat	PMID:12832103|RGD:2304184
Biological Process	GO:0035176	social behavior	Oxt	IDA		Rat	PMID:17540347|RGD:2304134
Biological Process	GO:0042713	sperm ejaculation	Oxt	IDA		Rat	PMID:18552879|RGD:2300336
Biological Process	GO:0036269	swimming behavior	oxt	IMP	ZFIN:ZDB-GENO-220125-1	Zfish	PMID:31358991

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern