Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse P2rx1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes P2RX1
- Mouse genes P2rx1
- Rat genes P2rx1
- Zfish genes p2rx1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set P2rx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	P2rx1	IDA		Rat	PMID:16934235\|RGD:1642659
Molecular Function	GO:0005524	ATP binding	P2rx1	IMP		Rat	PMID:17287520\|RGD:1642651
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	P2rx1	IDA		Rat	PMID:16934235\|RGD:1642659
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	p2rx1	IDA		Zfish	PMID:18850305
Molecular Function	GO:0042802	identical protein binding	P2rx1	IPI	RGD:3240	Rat	PMID:15313628\|RGD:1581703
Molecular Function	GO:0042802	identical protein binding	P2rx1	IPI	RGD:3240	Rat	PMID:17287520\|RGD:1642651
Molecular Function	GO:0005261	monoatomic cation channel activity	P2RX1	IDA		Human	PMID:8834001
Molecular Function	GO:0005261	monoatomic cation channel activity	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:10638758
Molecular Function	GO:0000166	nucleotide binding	P2rx1	IDA		Rat	PMID:12237343\|RGD:727431
Molecular Function	GO:0097159	organic cyclic compound binding	P2rx1	IPI	CHEBI:34946	Rat	PMID:12237343\|RGD:727431
Molecular Function	GO:0005515	protein binding	P2RX1	IPI	UniProtKB:Q9BQA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	P2rx1	IPI	RGD:620251	Rat	PMID:15313628\|RGD:1581703
Molecular Function	GO:0044877	protein-containing complex binding	P2rx1	IDA		Rat	PMID:15313628\|RGD:1581703
Molecular Function	GO:0001614	purinergic nucleotide receptor activity	P2RX1	IDA		Human	PMID:8834001
Molecular Function	GO:0001614	purinergic nucleotide receptor activity	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:10638758
Molecular Function	GO:0043924	suramin binding	P2rx1	IDA		Rat	PMID:12237343\|RGD:727431
Cellular Component	GO:0009897	external side of plasma membrane	P2rx1	IDA		Mouse	PMID:11570704
Cellular Component	GO:0098978	glutamatergic synapse	P2rx1	EXP		Rat	PMID:16000618\|RGD:1581702
Cellular Component	GO:0098978	glutamatergic synapse	P2rx1	IDA		Rat	PMID:16000618\|RGD:1581702
Cellular Component	GO:0045121	membrane raft	P2rx1	IDA		Rat	PMID:16006561\|RGD:1581648
Cellular Component	GO:0043005	neuron projection	P2rx1	IDA		Rat	PMID:16000618\|RGD:1581702
Cellular Component	GO:0005886	plasma membrane	P2rx1	IDA		Rat	PMID:11205062\|RGD:729097
Cellular Component	GO:0005886	plasma membrane	P2rx1	IDA		Rat	PMID:15313628\|RGD:1581703
Cellular Component	GO:0045211	postsynaptic membrane	P2rx1	IDA		Mouse	PMID:11668586
Cellular Component	GO:0045211	postsynaptic membrane	P2rx1	IDA		Rat	PMID:26801076\|RGD:13702236
Cellular Component	GO:0048787	presynaptic active zone membrane	P2rx1	IDA		Rat	PMID:16000618\|RGD:1581702
Cellular Component	GO:0032991	protein-containing complex	P2rx1	IDA		Rat	PMID:17287520\|RGD:1642651
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	P2rx1	IDA		Mouse	PMID:16325464
Biological Process	GO:0046513	ceramide biosynthetic process	P2rx1	IDA		Mouse	PMID:16325464
Biological Process	GO:0051649	establishment of localization in cell	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:10638758
Biological Process	GO:0051649	establishment of localization in cell	P2rx1	IGI	MGI:MGI:1918089	Mouse	PMID:15914557
Biological Process	GO:0051649	establishment of localization in cell	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:15914557
Biological Process	GO:0051649	establishment of localization in cell	P2rx1	IGI	MGI:MGI:105049	Mouse	PMID:15914557
Biological Process	GO:0007320	insemination	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:10638758
Biological Process	GO:0098655	monoatomic cation transmembrane transport	P2rx1	IDA		Rat	PMID:7523951\|RGD:728990
Biological Process	GO:0034220	monoatomic ion transmembrane transport	P2rx1	IMP		Rat	PMID:14625300\|RGD:1581712
Biological Process	GO:0006811	monoatomic ion transport	P2RX1	IDA		Human	PMID:8834001
Biological Process	GO:0006811	monoatomic ion transport	P2rx1	IGI	MGI:MGI:1918089	Mouse	PMID:15914557
Biological Process	GO:0006811	monoatomic ion transport	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:15914557
Biological Process	GO:0006811	monoatomic ion transport	P2rx1	IGI	MGI:MGI:105049	Mouse	PMID:15914557
Biological Process	GO:0006811	monoatomic ion transport	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:10638758
Biological Process	GO:0019228	neuronal action potential	P2rx1	IDA		Rat	PMID:16934235\|RGD:1642659
Biological Process	GO:0030168	platelet activation	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:12913094
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	P2rx1	IDA		Rat	PMID:12237343\|RGD:727431
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	P2rx1	IGI	MGI:MGI:105049	Mouse	PMID:15914557
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	P2rx1	IGI	MGI:MGI:1918089	Mouse	PMID:15914557
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:15914557
Biological Process	GO:0008217	regulation of blood pressure	P2rx1	IMP		Rat	PMID:14679185\|RGD:1581708
Biological Process	GO:0051924	regulation of calcium ion transport	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:16920810
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	P2rx1	EXP		Rat	PMID:16000618\|RGD:1581702
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	P2rx1	IDA		Rat	PMID:16000618\|RGD:1581702
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	P2rx1	IEP		Rat	PMID:16000618\|RGD:1581702
Biological Process	GO:0006940	regulation of smooth muscle contraction	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:10638758
Biological Process	GO:0006940	regulation of smooth muscle contraction	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:11570704
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	P2rx1	EXP		Rat	PMID:16000618\|RGD:1581702
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	P2rx1	IDA		Rat	PMID:16000618\|RGD:1581702
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	P2rx1	IEP		Rat	PMID:16000618\|RGD:1581702
Biological Process	GO:0003056	regulation of vascular associated smooth muscle contraction	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:16920810
Biological Process	GO:0019229	regulation of vasoconstriction	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:14679185
Biological Process	GO:0033198	response to ATP	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:14679185
Biological Process	GO:0033198	response to ATP	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:14722245
Biological Process	GO:0010033	response to organic substance	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:15914557
Biological Process	GO:0002554	serotonin secretion by platelet	P2rx1	IMP	MGI:MGI:2181608	Mouse	PMID:12913094
Biological Process	GO:0035249	synaptic transmission, glutamatergic	P2rx1	IMP		Rat	PMID:16000618\|RGD:1581702

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.