Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes P2RX5
  • Mouse genes P2rx5
  • Rat genes P2rx5
  • Zfish genes p2rx5,p2rx8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set P2rx5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Molecular Function	GO:0005524	ATP binding	p2rx5	IDA		Zfish	PMID:12127972
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	P2rx5	IDA		Mouse	PMID:11404011
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	P2rx5	IDA		Rat	PMID:12135987|RGD:729229
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	p2rx5	IDA		Zfish	PMID:12127972
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	p2rx5	IDA		Zfish	PMID:14580944
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	p2rx5	IDA		Zfish	PMID:18850305
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	p2rx5	IMP	ZFIN:ZDB-MRPHLNO-090127-1	Zfish	PMID:18850305
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	p2rx8	IDA		Zfish	PMID:14580944
Molecular Function	GO:0042802	identical protein binding	P2rx5	IPI	RGD:620256	Rat	PMID:15313628|RGD:1581703
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Cellular Component	GO:0005829	cytosol	P2RX5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Cellular Component	GO:0005886	plasma membrane	p2rx5	IDA		Zfish	PMID:18850305
Biological Process	GO:0060079	excitatory postsynaptic potential	P2rx5	IDA		Mouse	MGI:MGI:2136502|PMID:11404011
Biological Process	GO:0060079	excitatory postsynaptic potential	p2rx8	IDA		Zfish	PMID:14580944|ZFIN:ZDB-PUB-031031-8
Biological Process	GO:0098655	monoatomic cation transmembrane transport	P2rx5	IDA		Mouse	MGI:MGI:2136502|PMID:11404011
Biological Process	GO:0098655	monoatomic cation transmembrane transport	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Biological Process	GO:0098655	monoatomic cation transmembrane transport	p2rx8	IDA		Zfish	PMID:14580944|ZFIN:ZDB-PUB-031031-8
Biological Process	GO:0006812	monoatomic cation transport	p2rx5	IDA		Zfish	PMID:12127972
Biological Process	GO:0006812	monoatomic cation transport	p2rx5	IMP	ZFIN:ZDB-MRPHLNO-090127-1	Zfish	PMID:18850305
Biological Process	GO:0006812	monoatomic cation transport	p2rx5	IDA		Zfish	PMID:14580944
Biological Process	GO:0006812	monoatomic cation transport	p2rx8	IDA		Zfish	PMID:14580944
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Biological Process	GO:0043416	regulation of skeletal muscle tissue regeneration	P2rx5	IMP		Rat	PMID:12135987|RGD:729229
Biological Process	GO:0033198	response to ATP	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Biological Process	GO:0051592	response to calcium ion	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Biological Process	GO:0009268	response to pH	P2rx5	IDA		Rat	PMID:12237343|RGD:727431
Biological Process	GO:0010043	response to zinc ion	P2rx5	IDA		Rat	PMID:12237343|RGD:727431

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern