Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes P2RX6
  • Mouse genes P2rx6
  • Rat genes P2rx6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set P2rx6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	P2rx6	IDA		Rat	PMID:8786426|RGD:729425
Molecular Function	GO:0005515	protein binding	P2rx6	IPI	UniProtKB:P49653	Rat	PMID:24815693|RGD:8693375
Molecular Function	GO:0044877	protein-containing complex binding	P2rx6	IDA		Rat	PMID:17449665|RGD:1642655
Cellular Component	GO:0030054	cell junction	P2RX6	IDA		Human	PMID:12088286
Cellular Component	GO:0005737	cytoplasm	P2RX6	IDA		Human	PMID:12088286
Cellular Component	GO:0043197	dendritic spine	P2rx6	IDA		Rat	PMID:11160443|RGD:1642669
Cellular Component	GO:0098978	glutamatergic synapse	P2rx6	IDA		Rat	PMID:11160443|RGD:1642669
Cellular Component	GO:0016020	membrane	P2rx6	IDA		Rat	PMID:17449665|RGD:1642655
Cellular Component	GO:0043025	neuronal cell body	P2rx6	IDA		Rat	PMID:11160443|RGD:1642669
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	P2rx6	IDA		Rat	PMID:11160443|RGD:1642669
Cellular Component	GO:0014069	postsynaptic density	P2rx6	IDA		Rat	PMID:11160443|RGD:1642669
Cellular Component	GO:0099634	postsynaptic specialization membrane	P2rx6	IDA		Rat	PMID:11160443|RGD:1642669
Cellular Component	GO:0043235	receptor complex	P2RX6	IDA		Human	PMID:15313628

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern