Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PABPN1
  • Mouse genes Pabpn1
  • Rat genes Pabpn1
  • Zfish genes pabpn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pabpn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PABPN1	IPI	UniProtKB:Q13573	Human	PMID:11371506
Molecular Function	GO:0005515	protein binding	PABPN1	IPI	UniProtKB:O43809	Human	PMID:15169763
Molecular Function	GO:0005515	protein binding	PABPN1	IPI	UniProtKB:Q7Z333	Human	PMID:19515850
Molecular Function	GO:0005515	protein binding	PABPN1	IPI	UniProtKB:Q13573	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	PABPN1	IPI	UniProtKB:P11940	Human	PMID:23665581
Molecular Function	GO:0005515	protein binding	PABPN1	IPI	UniProtKB:P17844	Human	PMID:23788676
Molecular Function	GO:0005515	protein binding	PABPN1	IPI	UniProtKB:O60293	Human	PMID:27871484
Molecular Function	GO:0005515	protein binding	Pabpn1	IPI	UniProtKB:P22893	Mouse	MGI:MGI:5795816|PMID:22844456
Molecular Function	GO:0003723	RNA binding	PABPN1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PABPN1	HDA		Human	PMID:22681889
Molecular Function	GO:0070063	RNA polymerase binding	Pabpn1	IDA		Mouse	MGI:MGI:5795816|PMID:22844456
Cellular Component	GO:0042405	nuclear inclusion body	PABPN1	IDA		Human	PMID:27209344
Cellular Component	GO:0042405	nuclear inclusion body	Pabpn1	IDA		Rat	PMID:18255312|RGD:9686377
Cellular Component	GO:0005634	nucleus	PABPN1	IDA		Human	PMID:19364924
Cellular Component	GO:0005634	nucleus	PABPN1	IDA		Human	PMID:27209344
Cellular Component	GO:0005634	nucleus	Pabpn1	IDA		Mouse	MGI:MGI:5795816|PMID:22844456
Cellular Component	GO:0005634	nucleus	Pabpn1	IDA		Rat	PMID:14976164|RGD:1598686
Cellular Component	GO:1990904	ribonucleoprotein complex	PABPN1	IDA		Human	PMID:17289661
Cellular Component	GO:1990904	ribonucleoprotein complex	Pabpn1	IDA		Mouse	MGI:MGI:5795816|PMID:22844456
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Pabpn1	IMP		Mouse	MGI:MGI:5795816|PMID:22844456
Biological Process	GO:0000165	MAPK cascade	Pabpn1	IMP		Mouse	MGI:MGI:5795816|PMID:22844456
Biological Process	GO:0016973	poly(A)+ mRNA export from nucleus	PABPN1	IMP		Human	PMID:19364924
Biological Process	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity	Pabpn1	IMP		Mouse	MGI:MGI:5795816|PMID:22844456

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern