Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PACRG
  • Mouse genes Pacrg
  • Rat genes
  • Zfish genes pacrg
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pacrg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	PACRG	IDA		Human	PMID:14532270
Molecular Function	GO:0043014	alpha-tubulin binding	PACRG	IDA		Human	PMID:14532270
Molecular Function	GO:0048487	beta-tubulin binding	PACRG	IDA		Human	PMID:14532270
Molecular Function	GO:0001664	G protein-coupled receptor binding	PACRG	IPI	UniProtKB:O15354	Human	PMID:14532270
Molecular Function	GO:0031072	heat shock protein binding	PACRG	IPI	UniProtKB:P11142	Human	PMID:14532270
Molecular Function	GO:0030544	Hsp70 protein binding	PACRG	IDA		Human	PMID:14532270
Molecular Function	GO:0051879	Hsp90 protein binding	PACRG	IDA		Human	PMID:14532270
Molecular Function	GO:0005515	protein binding	Pacrg	IPI	UniProtKB:Q61845	Mouse	MGI:MGI:4366099|PMID:19805151
Molecular Function	GO:0005515	protein binding	Pacrg	IPI	PR:Q61845	Mouse	PMID:25715396
Molecular Function	GO:0051087	protein-folding chaperone binding	PACRG	IPI	UniProtKB:P17987	Human	PMID:14532270
Molecular Function	GO:0051087	protein-folding chaperone binding	PACRG	IPI	UniProtKB:P40227	Human	PMID:14532270
Molecular Function	GO:0051087	protein-folding chaperone binding	PACRG	IPI	UniProtKB:P48643	Human	PMID:14532270
Molecular Function	GO:0051087	protein-folding chaperone binding	PACRG	IPI	UniProtKB:P49368	Human	PMID:14532270
Molecular Function	GO:0051087	protein-folding chaperone binding	PACRG	IPI	UniProtKB:P50990	Human	PMID:14532270
Molecular Function	GO:0051087	protein-folding chaperone binding	PACRG	IPI	UniProtKB:P78371	Human	PMID:14532270
Molecular Function	GO:0051087	protein-folding chaperone binding	PACRG	IPI	UniProtKB:Q99832	Human	PMID:14532270
Molecular Function	GO:0031625	ubiquitin protein ligase binding	PACRG	IPI	UniProtKB:O60260	Human	PMID:14532270
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Pacrg	IPI	UniProtKB:Q9WVS6	Mouse	MGI:MGI:5586802|PMID:14532270
Cellular Component	GO:0044297	cell body	Pacrg	IDA		Mouse	PMID:19463890
Cellular Component	GO:0005929	cilium	Pacrg	IDA		Mouse	PMID:19463890
Cellular Component	GO:0005829	cytosol	PACRG	IDA		Human	PMID:14532270
Cellular Component	GO:0005829	cytosol	Pacrg	IDA		Mouse	MGI:MGI:5586802|PMID:14532270
Cellular Component	GO:0002177	manchette	Pacrg	IDA		Mouse	PMID:25715396
Cellular Component	GO:0005739	mitochondrion	Pacrg	HDA		Mouse	PMID:18614015
Cellular Component	GO:0043005	neuron projection	PACRG	IDA		Human	PMID:14532270
Cellular Component	GO:0043005	neuron projection	Pacrg	IDA		Mouse	MGI:MGI:5586802|PMID:14532270
Cellular Component	GO:0005634	nucleus	PACRG	HDA		Human	PMID:21630459
Cellular Component	GO:0097225	sperm midpiece	Pacrg	IDA		Mouse	PMID:15148410
Cellular Component	GO:0031982	vesicle	PACRG	IDA		Human	PMID:14532270
Cellular Component	GO:0031982	vesicle	Pacrg	IDA		Mouse	MGI:MGI:5586802|PMID:14532270
Biological Process	GO:0007368	determination of left/right symmetry	pacrg	IMP	ZFIN:ZDB-MRPHLNO-180926-2	Zfish	PMID:29843777
Biological Process	GO:0060548	negative regulation of cell death	PACRG	IMP		Human	PMID:14532270
Biological Process	GO:0060548	negative regulation of cell death	Pacrg	IMP		Mouse	MGI:MGI:5586802|PMID:14532270
Biological Process	GO:0008104	protein localization	Pacrg	IMP	MGI:MGI:1856539	Mouse	PMID:25715396
Biological Process	GO:0007286	spermatid development	Pacrg	IGI	MGI:MGI:97837	Mouse	PMID:15148410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern