Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAF1
  • Mouse genes Paf1
  • Rat genes Paf1
  • Zfish genes paf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Paf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Paf1	IDA		Mouse	PMID:22252316
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P24928	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P24928	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6PD62	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6PGP7	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q8WVC0	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q92541	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P51965	Human	PMID:16307923
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:19410543
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6PD62	Human	PMID:19410543
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q8WVC0	Human	PMID:19410543
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q92541	Human	PMID:19410543
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P23193	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P24928	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6PD62	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q8WVC0	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q92541	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q03164	Human	PMID:20541477
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P51116	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:B2BUF1	Human	PMID:22419161
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6PD62	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q8WVC0	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q92541	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P04792	Human	PMID:25277244
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:P51116	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q8WVC0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6PD62	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q8WVC0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q6P1J9	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:A0A455ZAR2	Human	PMID:30367041
Molecular Function	GO:0005515	protein binding	PAF1	IPI	UniProtKB:Q8WVC0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Paf1	IPI	UniProtKB:P83870	Mouse	MGI:MGI:6203683|PMID:27749823
Molecular Function	GO:0005515	protein binding	Paf1	IPI	PR:Q5XJE5	Mouse	PMID:22252316
Molecular Function	GO:0000993	RNA polymerase II complex binding	PAF1	IDA		Human	PMID:15923622
Cellular Component	GO:0016593	Cdc73/Paf1 complex	PAF1	IDA		Human	PMID:16307923
Cellular Component	GO:0016593	Cdc73/Paf1 complex	PAF1	IDA		Human	PMID:20178742
Cellular Component	GO:0016593	Cdc73/Paf1 complex	Paf1	IPI	UniProtKB:Q8JZM7	Mouse	MGI:MGI:6203683|PMID:27749823
Cellular Component	GO:0016593	Cdc73/Paf1 complex	paf1	IDA		Zfish	PMID:21338598
Cellular Component	GO:0005737	cytoplasm	PAF1	IDA		Human	PMID:22046413
Cellular Component	GO:0001650	fibrillar center	PAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	PAF1	IDA		Human	PMID:22046413
Cellular Component	GO:0005654	nucleoplasm	PAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	paf1	IDA		Zfish	PMID:21338598
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Paf1	IDA		Mouse	MGI:MGI:5319608|PMID:17911113
Biological Process	GO:0001711	endodermal cell fate commitment	Paf1	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:0007507	heart development	paf1	IMP		Zfish	PMID:21338598|ZFIN:ZDB-PUB-110316-17
Biological Process	GO:0006378	mRNA polyadenylation	PAF1	IMP		Human	PMID:21329879
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	PAF1	IDA		Human	PMID:20541477
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Paf1	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:0014032	neural crest cell development	paf1	IMP	ZFIN:ZDB-GENO-210212-7	Zfish	PMID:31784460
Biological Process	GO:1902808	positive regulation of cell cycle G1/S phase transition	PAF1	IMP		Human	PMID:15923622
Biological Process	GO:0031442	positive regulation of mRNA 3'-end processing	PAF1	IMP		Human	PMID:21329879
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PAF1	IDA		Human	PMID:16307923
Biological Process	GO:0034504	protein localization to nucleus	PAF1	IMP		Human	PMID:22046413
Biological Process	GO:0019827	stem cell population maintenance	Paf1	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:0006368	transcription elongation by RNA polymerase II	PAF1	IDA		Human	PMID:20178742

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern