Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pafah1b1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PAFAH1B1
- Mouse genes Pafah1b1
- Rat genes Pafah1b1
- Zfish genes pafah1b1a,pafah1b1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pafah1b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070840	dynein complex binding	PAFAH1B1	IDA		Human	PMID:11889140
Molecular Function	GO:0045505	dynein intermediate chain binding	Pafah1b1	IDA		Rat	PMID:11056530\|RGD:1601500
Molecular Function	GO:0042802	identical protein binding	Pafah1b1	IPI	PR:P63005	Mouse	PMID:11344260
Molecular Function	GO:0008017	microtubule binding	Pafah1b1	IDA		Mouse	PMID:11163259
Molecular Function	GO:0051219	phosphoprotein binding	Pafah1b1	IPI	PR:P97318	Mouse	PMID:14578885
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q9GZM8	Human	PMID:10931877
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:O35685	Human	PMID:11163258
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q9CZA6	Human	PMID:11163258
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:P30622	Human	PMID:11940666
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q8IVD9	Human	PMID:16754861
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:P07900	Human	PMID:20133715
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q8WVJ2	Human	PMID:20133715
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q9CZA6	Human	PMID:20360068
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:M0R2J8	Human	PMID:22159412
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q9GZM8	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q9NRI5	Human	PMID:29961565
Molecular Function	GO:0005515	protein binding	PAFAH1B1	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:Q9GZM8	Mouse	MGI:MGI:4442527\|PMID:20360068
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:Q9GZM8	Mouse	MGI:MGI:5705193\|PMID:26496610
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:Q9GZM8	Mouse	MGI:MGI:5297250\|PMID:22114287
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:Q9ERR1\|UniProtKB:Q9GZM8	Mouse	MGI:MGI:5926211\|PMID:17997972
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:P68402\|UniProtKB:Q9GZM8	Mouse	MGI:MGI:6467922\|PMID:15572112
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:Q61205\|UniProtKB:Q9ERR1	Mouse	MGI:MGI:1932152\|PMID:11231056
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:Q9ERR1	Mouse	MGI:MGI:2665158\|PMID:12796778
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:Q155P7	Mouse	MGI:MGI:3583501\|PMID:15939891
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	PR:Q922J3	Mouse	PMID:11940666
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	PR:Q9ERR1	Mouse	PMID:18331715
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	PR:O08788	Mouse	PMID:22073305
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	PR:O88485	Mouse	PMID:22073305
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	PR:Q7TSI1	Mouse	PMID:22073305
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	PR:Q8BG40	Mouse	PMID:16203747
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	UniProtKB:B1AWC9	Mouse	PMID:18983980
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	RGD:631359	Rat	PMID:17202468\|RGD:4107038
Molecular Function	GO:0005515	protein binding	Pafah1b1	IPI	RGD:3215	Rat	PMID:9601647\|RGD:4107037
Molecular Function	GO:0044877	protein-containing complex binding	Pafah1b1	IPI	RGD:631359\|RGD:621235\|RGD:62000\|RGD:1303035	Rat	PMID:17202468\|RGD:4107038
Cellular Component	GO:0008247	1-alkyl-2-acetylglycerophosphocholine esterase complex	Pafah1b1	IDA		Rat	PMID:9660828\|RGD:4107046
Cellular Component	GO:0000235	astral microtubule	PAFAH1B1	IDA		Human	PMID:11940666
Cellular Component	GO:0030424	axon	Pafah1b1	IDA		Rat	PMID:17202468\|RGD:4107038
Cellular Component	GO:0005938	cell cortex	PAFAH1B1	IDA		Human	PMID:11940666
Cellular Component	GO:0031252	cell leading edge	Pafah1b1	IDA		Mouse	PMID:14691133
Cellular Component	GO:0090724	central region of growth cone	Pafah1b1	IDA		Rat	PMID:17202468\|RGD:4107038
Cellular Component	GO:0005813	centrosome	PAFAH1B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	PAFAH1B1	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	Pafah1b1	IDA		Mouse	PMID:11163260
Cellular Component	GO:0005813	centrosome	Pafah1b1	IDA		Mouse	PMID:11163259
Cellular Component	GO:0005737	cytoplasm	Pafah1b1	IDA		Mouse	PMID:12950100
Cellular Component	GO:0005737	cytoplasm	Pafah1b1	IDA		Mouse	PMID:29078390
Cellular Component	GO:0005737	cytoplasm	Pafah1b1	IDA		Mouse	PMID:12551946
Cellular Component	GO:0005737	cytoplasm	pafah1b1a	IDA		Zfish	PMID:19657569
Cellular Component	GO:0005737	cytoplasm	pafah1b1b	IDA		Zfish	PMID:19657569
Cellular Component	GO:0005829	cytosol	Pafah1b1	IDA		Rat	PMID:17202468\|RGD:4107038
Cellular Component	GO:0005829	cytosol	Pafah1b1	IDA		Rat	PMID:9660828\|RGD:4107046
Cellular Component	GO:0070062	extracellular exosome	PAFAH1B1	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Pafah1b1	IMP		Mouse	PMID:23483716
Cellular Component	GO:0098978	glutamatergic synapse	Pafah1b1	IDA		Mouse	PMID:23483716
Cellular Component	GO:0030426	growth cone	Pafah1b1	IDA		Rat	PMID:11056530\|RGD:1601500
Cellular Component	GO:0005871	kinesin complex	Pafah1b1	IDA		Rat	PMID:17202468\|RGD:4107038
Cellular Component	GO:0000776	kinetochore	PAFAH1B1	IDA		Human	PMID:11056532
Cellular Component	GO:0000776	kinetochore	PAFAH1B1	IDA		Human	PMID:11889140
Cellular Component	GO:0000776	kinetochore	PAFAH1B1	IDA		Human	PMID:11940666
Cellular Component	GO:0005875	microtubule associated complex	PAFAH1B1	IDA		Human	PMID:11889140
Cellular Component	GO:0005875	microtubule associated complex	Pafah1b1	IDA		Mouse	PMID:11163259
Cellular Component	GO:0015630	microtubule cytoskeleton	Pafah1b1	IDA		Mouse	PMID:17314247
Cellular Component	GO:0015630	microtubule cytoskeleton	Pafah1b1	IDA		Mouse	PMID:13129914
Cellular Component	GO:0031514	motile cilium	Pafah1b1	IDA		Mouse	PMID:17314247
Cellular Component	GO:0043005	neuron projection	Pafah1b1	IDA		Rat	PMID:11001923\|RGD:4107039
Cellular Component	GO:0043025	neuronal cell body	Pafah1b1	IDA		Rat	PMID:11056530\|RGD:1601500
Cellular Component	GO:0005635	nuclear envelope	PAFAH1B1	IDA		Human	PMID:11940666
Cellular Component	GO:0005635	nuclear envelope	Pafah1b1	IDA		Rat	PMID:18809722\|RGD:8554736
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Pafah1b1	IDA		Mouse	PMID:14578885
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Pafah1b1	IDA		Mouse	PMID:29150182
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Pafah1b1	IMP		Mouse	PMID:29150182
Cellular Component	GO:0032420	stereocilium	Pafah1b1	IDA		Mouse	PMID:23533177
Cellular Component	GO:0031982	vesicle	Pafah1b1	IDA		Rat	PMID:11056530\|RGD:1601500
Biological Process	GO:0001675	acrosome assembly	Pafah1b1	IMP	MGI:MGI:2683481	Mouse	PMID:13129914
Biological Process	GO:0030036	actin cytoskeleton organization	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:14507966
Biological Process	GO:0008344	adult locomotory behavior	PAFAH1B1	IMP		Human	PMID:9063735
Biological Process	GO:0008344	adult locomotory behavior	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:10541472
Biological Process	GO:0001667	ameboidal-type cell migration	Pafah1b1	IMP		Mouse	PMID:22073305
Biological Process	GO:0045176	apical protein localization	pafah1b1b	IMP	ZFIN:ZDB-MRPHLNO-071201-1,ZFIN:ZDB-MRPHLNO-071201-3	Zfish	PMID:17785424
Biological Process	GO:0060117	auditory receptor cell development	Pafah1b1	IMP		Mouse	MGI:MGI:5477842\|PMID:23533177
Biological Process	GO:0007420	brain development	Pafah1b1	IEP		Rat	PMID:9660828\|RGD:4107046
Biological Process	GO:0048854	brain morphogenesis	PAFAH1B1	IMP		Human	PMID:9063735
Biological Process	GO:0048854	brain morphogenesis	pafah1b1a	IMP	ZFIN:ZDB-MRPHLNO-090820-2	Zfish	PMID:19657569
Biological Process	GO:0048854	brain morphogenesis	pafah1b1a	IMP	ZFIN:ZDB-MRPHLNO-090820-1	Zfish	PMID:19657569
Biological Process	GO:0048854	brain morphogenesis	pafah1b1a	IGI	ZFIN:ZDB-MRPHLNO-071201-1,ZFIN:ZDB-MRPHLNO-090820-1	Zfish	PMID:19657569
Biological Process	GO:0048854	brain morphogenesis	pafah1b1a	IGI	ZFIN:ZDB-MRPHLNO-071201-1,ZFIN:ZDB-MRPHLNO-090820-2	Zfish	PMID:19657569
Biological Process	GO:0048854	brain morphogenesis	pafah1b1b	IGI	ZFIN:ZDB-MRPHLNO-071201-1,ZFIN:ZDB-MRPHLNO-090820-1	Zfish	PMID:19657569
Biological Process	GO:0048854	brain morphogenesis	pafah1b1b	IGI	ZFIN:ZDB-MRPHLNO-071201-1,ZFIN:ZDB-MRPHLNO-090820-2	Zfish	PMID:19657569
Biological Process	GO:0048854	brain morphogenesis	pafah1b1b	IMP	ZFIN:ZDB-MRPHLNO-071201-1	Zfish	PMID:19657569
Biological Process	GO:0016477	cell migration	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:12629176
Biological Process	GO:0021987	cerebral cortex development	PAFAH1B1	IMP		Human	PMID:9063735
Biological Process	GO:0021987	cerebral cortex development	Pafah1b1	IGI	MGI:MGI:1914453	Mouse	PMID:18469343
Biological Process	GO:0021987	cerebral cortex development	Pafah1b1	IMP	MGI:MGI:2387783	Mouse	PMID:11344260
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Pafah1b1	IMP		Rat	PMID:16144905\|RGD:1601501
Biological Process	GO:0007268	chemical synaptic transmission	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:10729324
Biological Process	GO:0090102	cochlea development	Pafah1b1	IMP		Mouse	MGI:MGI:5477842\|PMID:23533177
Biological Process	GO:0021540	corpus callosum morphogenesis	PAFAH1B1	IMP		Human	PMID:9063735
Biological Process	GO:0043622	cortical microtubule organization	Pafah1b1	IMP		Mouse	MGI:MGI:5293247\|PMID:21844209
Biological Process	GO:0051660	establishment of centrosome localization	Pafah1b1	IMP		Rat	PMID:17618279\|RGD:4107031
Biological Process	GO:0051649	establishment of localization in cell	Pafah1b1	IMP		Mouse	PMID:22073305
Biological Process	GO:0000132	establishment of mitotic spindle orientation	PAFAH1B1	IMP		Human	PMID:11056532
Biological Process	GO:0042249	establishment of planar polarity of embryonic epithelium	Pafah1b1	IMP		Mouse	MGI:MGI:5477842\|PMID:23533177
Biological Process	GO:0021766	hippocampus development	Pafah1b1	IGI	MGI:MGI:1340044	Mouse	PMID:17330141
Biological Process	GO:0021766	hippocampus development	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:10729324
Biological Process	GO:1904936	interneuron migration	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:15331402
Biological Process	GO:0007254	JNK cascade	Pafah1b1	IGI	MGI:MGI:1100089	Mouse	PMID:22073305
Biological Process	GO:0021819	layer formation in cerebral cortex	Pafah1b1	IGI	MGI:MGI:1340044	Mouse	PMID:17330141
Biological Process	GO:0007611	learning or memory	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:10541472
Biological Process	GO:0051661	maintenance of centrosome location	Pafah1b1	IMP	MGI:MGI:2384060	Mouse	PMID:23533177
Biological Process	GO:0000226	microtubule cytoskeleton organization	Pafah1b1	IGI	MGI:MGI:1932915	Mouse	PMID:16107726
Biological Process	GO:0000226	microtubule cytoskeleton organization	Pafah1b1	IMP		Mouse	PMID:22073305
Biological Process	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity	Pafah1b1	IMP		Mouse	MGI:MGI:5477842\|PMID:23533177
Biological Process	GO:0031023	microtubule organizing center organization	PAFAH1B1	IMP		Human	PMID:11163258
Biological Process	GO:0007017	microtubule-based process	PAFAH1B1	IDA		Human	PMID:11940666
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Pafah1b1	IDA		Mouse	PMID:29150182
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Pafah1b1	IMP		Mouse	PMID:29150182
Biological Process	GO:0097529	myeloid leukocyte migration	Pafah1b1	IMP		Mouse	PMID:22073305
Biological Process	GO:0046329	negative regulation of JNK cascade	Pafah1b1	IGI	MGI:MGI:1100089	Mouse	PMID:22073305
Biological Process	GO:0010977	negative regulation of neuron projection development	Pafah1b1	IMP		Rat	PMID:18075262\|RGD:4107030
Biological Process	GO:0007405	neuroblast proliferation	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:12629176
Biological Process	GO:0050885	neuromuscular process controlling balance	PAFAH1B1	IMP		Human	PMID:9063735
Biological Process	GO:0050885	neuromuscular process controlling balance	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:10541472
Biological Process	GO:0001764	neuron migration	PAFAH1B1	IMP		Human	PMID:11163258
Biological Process	GO:0001764	neuron migration	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:14507966
Biological Process	GO:0001764	neuron migration	Pafah1b1	IGI	MGI:MGI:1932915	Mouse	PMID:16107726
Biological Process	GO:0001764	neuron migration	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:9697693
Biological Process	GO:0001764	neuron migration	Pafah1b1	IGI	MGI:MGI:894689	Mouse	PMID:12796778
Biological Process	GO:0001764	neuron migration	Pafah1b1	IMP		Rat	PMID:16144905\|RGD:1601501
Biological Process	GO:0051081	nuclear membrane disassembly	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:18809722
Biological Process	GO:0007097	nuclear migration	Pafah1b1	IMP		Rat	PMID:17618279\|RGD:4107031
Biological Process	GO:0007097	nuclear migration	pafah1b1b	IMP	ZFIN:ZDB-MRPHLNO-071201-3	Zfish	PMID:17785424
Biological Process	GO:0007097	nuclear migration	pafah1b1b	IMP	ZFIN:ZDB-MRPHLNO-071201-1	Zfish	PMID:17785424
Biological Process	GO:0007097	nuclear migration	pafah1b1b	IMP		Zfish	PMID:17785424
Biological Process	GO:0036035	osteoclast development	Pafah1b1	IMP		Mouse	PMID:22073305
Biological Process	GO:0045494	photoreceptor cell maintenance	pafah1b1b	IMP		Zfish	PMID:17785424
Biological Process	GO:0045773	positive regulation of axon extension	Pafah1b1	IMP		Rat	PMID:17202468\|RGD:4107038
Biological Process	GO:0045773	positive regulation of axon extension	Pafah1b1	IMP		Rat	PMID:17522326\|RGD:4107033
Biological Process	GO:0051130	positive regulation of cellular component organization	Pafah1b1	IMP		Mouse	MGI:MGI:5477842\|PMID:23533177
Biological Process	GO:0001961	positive regulation of cytokine-mediated signaling pathway	Pafah1b1	IMP		Mouse	PMID:22073305
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Pafah1b1	IMP		Mouse	MGI:MGI:5619436\|PMID:23483716
Biological Process	GO:0040019	positive regulation of embryonic development	Pafah1b1	IMP		Mouse	MGI:MGI:5477842\|PMID:23533177
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	Pafah1b1	IMP		Rat	PMID:11056532\|RGD:4107032
Biological Process	GO:0009306	protein secretion	Pafah1b1	IMP		Mouse	PMID:22073305
Biological Process	GO:0140650	radial glia-guided pyramidal neuron migration	Pafah1b1	IGI	MGI:MGI:1932915	Mouse	PMID:16107726
Biological Process	GO:0038026	reelin-mediated signaling pathway	Pafah1b1	IMP		Mouse	MGI:MGI:3769085\|PMID:17330141
Biological Process	GO:0043087	regulation of GTPase activity	Pafah1b1	IMP	MGI:MGI:2384054	Mouse	PMID:14507966
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	Pafah1b1	IMP		Mouse	MGI:MGI:5477842\|PMID:23533177
Biological Process	GO:0099175	regulation of postsynapse organization	Pafah1b1	IDA		Mouse	PMID:23483716
Biological Process	GO:0099175	regulation of postsynapse organization	Pafah1b1	IMP		Mouse	PMID:23483716
Biological Process	GO:0008090	retrograde axonal transport	Pafah1b1	IDA		Mouse	PMID:11163259
Biological Process	GO:0017145	stem cell division	Pafah1b1	IMP		Rat	PMID:16144905\|RGD:1601501
Biological Process	GO:0019226	transmission of nerve impulse	Pafah1b1	IMP	MGI:MGI:2387783	Mouse	PMID:17433713
Biological Process	GO:0047496	vesicle transport along microtubule	Pafah1b1	IGI	MGI:MGI:1914453	Mouse	PMID:16107726
Biological Process	GO:0047496	vesicle transport along microtubule	Pafah1b1	IGI	MGI:MGI:1932915	Mouse	PMID:16107726

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/02/2024 MGI 6.13

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.