Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAICS
  • Mouse genes Paics
  • Rat genes LOC100359876,Paics
  • Zfish genes paics
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Paics

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	PAICS	HDA		Human	PMID:25468996
Molecular Function	GO:0042802	identical protein binding	PAICS	IPI	UniProtKB:P22234	Human	PMID:16169070
Molecular Function	GO:0042802	identical protein binding	PAICS	IPI	UniProtKB:P22234	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	PAICS	IPI	UniProtKB:P22234	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	PAICS	IPI	UniProtKB:P22234	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	PAICS	IPI	UniProtKB:P22234	Human	PMID:32296183
Molecular Function	GO:0004638	phosphoribosylaminoimidazole carboxylase activity	PAICS	IDA		Human	PMID:27590927
Molecular Function	GO:0004638	phosphoribosylaminoimidazole carboxylase activity	PAICS	IMP		Human	PMID:31600779
Molecular Function	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	PAICS	IDA		Human	PMID:27590927
Molecular Function	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	PAICS	IMP		Human	PMID:31600779
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:P51116	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q6ZVK8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q8TBB1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:P51116	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q6ZVK8	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:P51116	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q969R5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q969R5	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:C9JJ79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q16543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q9UBW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAICS	IPI	UniProtKB:Q9Y4B4	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	PAICS	IDA		Human	PMID:25468996
Cellular Component	GO:0070062	extracellular exosome	PAICS	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	PAICS	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	PAICS	HDA		Human	PMID:19946888
Biological Process	GO:0044208	'de novo' AMP biosynthetic process	PAICS	IDA		Human	PMID:27590927
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	PAICS	IDA		Human	PMID:27590927
Biological Process	GO:0097294	'de novo' XMP biosynthetic process	PAICS	IDA		Human	PMID:27590927
Biological Process	GO:0043010	camera-type eye development	paics	IMP	ZFIN:ZDB-GENO-110302-1	Zfish	PMID:19570845
Biological Process	GO:0043009	chordate embryonic development	paics	IMP	ZFIN:ZDB-GENO-110302-6	Zfish	PMID:19570845
Biological Process	GO:0043009	chordate embryonic development	paics	IMP	ZFIN:ZDB-GENO-110302-3	Zfish	PMID:19570845
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Paics	IEP		Rat	PMID:7742366|RGD:633692
Biological Process	GO:0006177	GMP biosynthetic process	PAICS	IDA		Human	PMID:27590927
Biological Process	GO:0043473	pigmentation	paics	IMP	ZFIN:ZDB-GENO-110302-1	Zfish	PMID:19570845
Biological Process	GO:0009113	purine nucleobase biosynthetic process	PAICS	IDA		Human	PMID:31600779
Biological Process	GO:0060041	retina development in camera-type eye	paics	IMP	ZFIN:ZDB-GENO-040709-2	Zfish	PMID:15716491

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern