Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAK5
  • Mouse genes Pak5
  • Rat genes Pak5
  • Zfish genes pak5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pak5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q92530	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P60953	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:O60504	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P50402	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P51959	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8N5M1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q96BZ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q96CN9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q96EL1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q96SW2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9H257	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9H6L4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9UBK9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9Y3B2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8N5M1	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8WWY3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P51959	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8N5M1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q92530	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q96EL1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q96SW2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9H257	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9UBK9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:A0A024R8L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P26196	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P48730	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P60953	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q16825	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8IW93	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8NEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q8WWY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9BZW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:Q9H4E5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P60953	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P07196	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P16284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PAK5	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pak5	IDA		Mouse	PMID:12897128
Cellular Component	GO:0005829	cytosol	PAK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Pak5	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Pak5	IDA		Mouse	PMID:12897128
Cellular Component	GO:0031965	nuclear membrane	PAK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PAK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045202	synapse	Pak5	IDA		Mouse	PMID:24474471
Cellular Component	GO:0045202	synapse	Pak5	IEP		Mouse	PMID:24474471
Biological Process	GO:0007612	learning	Pak5	IGI	MGI:MGI:2679420	Mouse	PMID:18675265
Biological Process	GO:0007612	learning	Pak5	IGI	MGI:MGI:2679420	Mouse	PMID:23593460
Biological Process	GO:0007626	locomotory behavior	Pak5	IGI	MGI:MGI:2679420	Mouse	PMID:23593460
Biological Process	GO:0007626	locomotory behavior	Pak5	IGI	MGI:MGI:2679420	Mouse	PMID:18675265
Biological Process	GO:0007613	memory	Pak5	IGI	MGI:MGI:2679420	Mouse	PMID:23593460
Biological Process	GO:0007613	memory	Pak5	IGI	MGI:MGI:2679420	Mouse	PMID:18675265
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	Pak5	IDA		Mouse	PMID:12897128

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern