Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BUB1B-PAK6,PAK6
  • Mouse genes Pak6
  • Rat genes Pak6
  • Zfish genes pak6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pak6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	PAK6	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:P60953	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:Q5S007	Human	PMID:24510904
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:Q5S007	Human	PMID:24947832
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:Q9H4E5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:Q9H4E5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:P60953	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:Q96L33	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAK6	IPI	UniProtKB:P60953	Human	PMID:32707033
Cellular Component	GO:0030054	cell junction	PAK6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	PAK6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PAK6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Pak6	IDA		Mouse	PMID:25211037
Cellular Component	GO:0014069	postsynaptic density	Pak6	EXP		Mouse	PMID:25211037
Biological Process	GO:0007612	learning	Pak6	IGI	MGI:MGI:1920334	Mouse	PMID:23593460
Biological Process	GO:0007612	learning	Pak6	IGI	MGI:MGI:1920334	Mouse	PMID:18675265
Biological Process	GO:0007626	locomotory behavior	Pak6	IGI	MGI:MGI:1920334	Mouse	PMID:18675265
Biological Process	GO:0007626	locomotory behavior	Pak6	IGI	MGI:MGI:1920334	Mouse	PMID:23593460
Biological Process	GO:0007613	memory	Pak6	IGI	MGI:MGI:1920334	Mouse	PMID:23593460
Biological Process	GO:0007613	memory	Pak6	IGI	MGI:MGI:1920334	Mouse	PMID:18675265
Biological Process	GO:0140058	neuron projection arborization	Pak6	IMP		Mouse	PMID:29117290
Biological Process	GO:1990138	neuron projection extension	Pak6	IMP		Mouse	PMID:29117290

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern