Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAM
  • Mouse genes Pam
  • Rat genes Pam
  • Zfish genes pam
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Pam	IDA		Rat	PMID:19604476|RGD:6483513
Molecular Function	GO:0005507	copper ion binding	Pam	IDA		Rat	PMID:10504734|RGD:14390065
Molecular Function	GO:0005507	copper ion binding	Pam	IDA		Rat	PMID:16931045|RGD:2302417
Molecular Function	GO:0042802	identical protein binding	Pam	IPI	RGD:3252	Rat	PMID:11395514|RGD:2302422
Molecular Function	GO:0004598	peptidylamidoglycolate lyase activity	PAM	IDA		Human	PMID:12699694
Molecular Function	GO:0004598	peptidylamidoglycolate lyase activity	Pam	IDA		Rat	PMID:10079066|RGD:14390048
Molecular Function	GO:0004598	peptidylamidoglycolate lyase activity	Pam	IDA		Rat	PMID:16405966|RGD:2302419
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	PAM	IDA		Human	PMID:12699694
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	PAM	IDA		Human	PMID:2357221
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	Pam	IDA		Rat	PMID:10079066|RGD:14390048
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	Pam	IDA		Rat	PMID:16405966|RGD:2302419
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	pam	IMP	ZFIN:ZDB-GENO-180807-2	Zfish	PMID:29540787
Molecular Function	GO:0005515	protein binding	PAM	IPI	UniProtKB:O75901	Human	PMID:9837933
Molecular Function	GO:0005515	protein binding	Pam	IPI	RGD:1308360	Rat	PMID:15331630|RGD:1598417
Molecular Function	GO:0005515	protein binding	Pam	IPI	RGD:621865	Rat	PMID:8910496|RGD:728662
Molecular Function	GO:0005515	protein binding	Pam	IPI	UniProtKB:O88869	Rat	PMID:8910496|RGD:728662
Molecular Function	GO:0005515	protein binding	Pam	IPI	RGD:621329	Rat	PMID:9837933|RGD:633607
Molecular Function	GO:0005515	protein binding	Pam	IPI	UniProtKB:O88869	Rat	PMID:9837933|RGD:633607
Molecular Function	GO:0019901	protein kinase binding	Pam	IPI	RGD:2968	Rat	PMID:8910496|RGD:728662
Molecular Function	GO:0008270	zinc ion binding	PAM	IDA		Human	PMID:12699694
Molecular Function	GO:0008270	zinc ion binding	Pam	IDA		Rat	PMID:19604476|RGD:6483513
Cellular Component	GO:0009986	cell surface	Pam	IDA		Rat	PMID:15905171|RGD:6483550
Cellular Component	GO:0070062	extracellular exosome	PAM	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PAM	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Pam	IDA		Rat	PMID:16448835|RGD:2302418
Cellular Component	GO:0016020	membrane	PAM	HDA		Human	PMID:19946888
Cellular Component	GO:0043005	neuron projection	Pam	IDA		Rat	PMID:20202202|RGD:6483511
Cellular Component	GO:0043025	neuronal cell body	Pam	IDA		Rat	PMID:20202202|RGD:6483511
Cellular Component	GO:0043204	perikaryon	Pam	IDA		Rat	PMID:8910496|RGD:728662
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Pam	IDA		Rat	PMID:8663411|RGD:6483562
Cellular Component	GO:0005886	plasma membrane	Pam	IDA		Rat	PMID:8663411|RGD:6483562
Cellular Component	GO:0030141	secretory granule	Pam	IDA		Rat	PMID:15539631|RGD:2302421
Cellular Component	GO:0030667	secretory granule membrane	Pam	IDA		Rat	PMID:15158736|RGD:6483559
Cellular Component	GO:0005802	trans-Golgi network	Pam	IDA		Rat	PMID:20573687|RGD:6483496
Biological Process	GO:0007417	central nervous system development	Pam	IEP		Rat	PMID:9441675|RGD:2302426
Biological Process	GO:0097711	ciliary basal body-plasma membrane docking	pam	IMP	ZFIN:ZDB-GENO-180807-2	Zfish	PMID:29540787
Biological Process	GO:0060271	cilium assembly	pam	IMP	ZFIN:ZDB-GENO-180807-2	Zfish	PMID:29540787
Biological Process	GO:0062112	fatty acid primary amide biosynthetic process	Pam	IDA		Rat	PMID:10079066|RGD:14390048
Biological Process	GO:0007507	heart development	Pam	IEP		Rat	PMID:9441675|RGD:2302426
Biological Process	GO:0007595	lactation	Pam	IEP		Rat	PMID:16448835|RGD:2302418
Biological Process	GO:0060173	limb development	Pam	IEP		Rat	PMID:9441675|RGD:2302426
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Pam	IDA		Rat	PMID:8660675|RGD:6483540
Biological Process	GO:0060135	maternal process involved in female pregnancy	Pam	IEP		Rat	PMID:9441675|RGD:2302426
Biological Process	GO:0030033	microvillus assembly	pam	IMP	ZFIN:ZDB-GENO-180807-2	Zfish	PMID:29540787
Biological Process	GO:0042476	odontogenesis	Pam	IEP		Rat	PMID:9441675|RGD:2302426
Biological Process	GO:0022602	ovulation cycle process	Pam	IEP		Rat	PMID:9618561|RGD:2302425
Biological Process	GO:0001519	peptide amidation	PAM	IDA		Human	PMID:12699694
Biological Process	GO:0001519	peptide amidation	PAM	IDA		Human	PMID:2357221
Biological Process	GO:0001519	peptide amidation	Pam	IDA		Rat	PMID:10079066|RGD:14390048
Biological Process	GO:0001519	peptide amidation	Pam	IDA		Rat	PMID:2999151|RGD:6483598
Biological Process	GO:0006518	peptide metabolic process	Pam	IDA		Rat	PMID:18818385|RGD:6483514
Biological Process	GO:0018032	protein amidation	Pam	IDA		Rat	PMID:12075461|RGD:6483570
Biological Process	GO:0019538	protein metabolic process	Pam	IDA		Rat	PMID:16098968|RGD:6483548
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Pam	IMP		Rat	PMID:11251076|RGD:6483597
Biological Process	GO:0050708	regulation of protein secretion	Pam	IMP		Rat	PMID:11251076|RGD:6483597
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pam	IMP		Rat	PMID:20573687|RGD:6483496
Biological Process	GO:0046688	response to copper ion	Pam	IEP		Rat	PMID:15629125|RGD:2302420
Biological Process	GO:0032355	response to estradiol	Pam	IEP		Rat	PMID:9618561|RGD:2302425
Biological Process	GO:0051384	response to glucocorticoid	Pam	IEP		Rat	PMID:10347250|RGD:2302424
Biological Process	GO:0001666	response to hypoxia	Pam	IEP		Rat	PMID:18818385|RGD:6483514
Biological Process	GO:0009268	response to pH	Pam	IDA		Rat	PMID:11395514|RGD:2302422
Biological Process	GO:0009410	response to xenobiotic stimulus	Pam	IDA		Rat	PMID:10347250|RGD:2302424
Biological Process	GO:0010043	response to zinc ion	PAM	IDA		Human	PMID:12699694
Biological Process	GO:0009404	toxin metabolic process	Pam	IDA		Rat	PMID:12721493|RGD:6483565

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern