Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PANK2
  • Mouse genes Pank2
  • Rat genes
  • Zfish genes pank2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pank2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004594	pantothenate kinase activity	PANK2	IMP		Human	PMID:15659606
Molecular Function	GO:0004594	pantothenate kinase activity	PANK2	IMP		Human	PMID:16272150
Molecular Function	GO:0004594	pantothenate kinase activity	PANK2	IMP		Human	PMID:17242360
Molecular Function	GO:0004594	pantothenate kinase activity	Pank2	IMP		Mouse	MGI:MGI:6508498|PMID:17379144
Molecular Function	GO:0004594	pantothenate kinase activity	Pank2	IMP	MGI:MGI:2176050,MGI:MGI:5446719	Mouse	PMID:22815849
Molecular Function	GO:0004594	pantothenate kinase activity	Pank2	IDA		Mouse	PMID:17825826
Molecular Function	GO:0004594	pantothenate kinase activity	Pank2	IGI	UniProtKB:C8UKN1	Mouse	PMID:11479594
Cellular Component	GO:0005829	cytosol	PANK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Pank2	IDA		Mouse	PMID:17825826
Cellular Component	GO:0005758	mitochondrial intermembrane space	PANK2	IDA		Human	PMID:23152917
Cellular Component	GO:0005739	mitochondrion	PANK2	IDA		Human	PMID:15659606
Cellular Component	GO:0005739	mitochondrion	PANK2	IDA		Human	PMID:23152917
Cellular Component	GO:0005739	mitochondrion	Pank2	IMP	MGI:MGI:3514020	Mouse	PMID:22983956
Cellular Component	GO:0005739	mitochondrion	Pank2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005634	nucleus	PANK2	IDA		Human	PMID:23152917
Biological Process	GO:0009060	aerobic respiration	Pank2	IMP	MGI:MGI:3514020	Mouse	PMID:22983956
Biological Process	GO:0001525	angiogenesis	PANK2	IMP		Human	PMID:30221726
Biological Process	GO:0015937	coenzyme A biosynthetic process	Pank2	IMP	MGI:MGI:2176050,MGI:MGI:5446719	Mouse	PMID:22815849
Biological Process	GO:0070584	mitochondrion morphogenesis	Pank2	IMP	MGI:MGI:3514020	Mouse	PMID:22983956
Biological Process	GO:0007399	nervous system development	pank2	IMP	ZFIN:ZDB-MRPHLNO-160310-4	Zfish	PMID:26476142
Biological Process	GO:1904251	regulation of bile acid metabolic process	PANK2	IMP		Human	PMID:22221393
Biological Process	GO:0019217	regulation of fatty acid metabolic process	PANK2	IMP		Human	PMID:22221393
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	Pank2	IMP	MGI:MGI:3514020	Mouse	PMID:22983956
Biological Process	GO:0090207	regulation of triglyceride metabolic process	PANK2	IMP		Human	PMID:22221393
Biological Process	GO:0007286	spermatid development	Pank2	IMP	MGI:MGI:3514020	Mouse	PMID:15525657
Biological Process	GO:0001944	vasculature development	pank2	IMP	ZFIN:ZDB-MRPHLNO-160310-4	Zfish	PMID:26476142

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern