Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARD6A
  • Mouse genes Pard6a
  • Rat genes Pard6a
  • Zfish genes pard6a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pard6a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030742	GTP-dependent protein binding	Pard6a	IPI	UniProtKB:P60766	Mouse	MGI:MGI:3687818|PMID:10954424
Molecular Function	GO:0030742	GTP-dependent protein binding	Pard6a	IPI	UniProtKB:P63001	Mouse	MGI:MGI:3687818|PMID:10954424
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P60953	Human	PMID:10934474
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P60766	Human	PMID:10954424
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:11257119
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q8TEW0	Human	PMID:11257119
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P60953	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P63000	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q05513	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P60953	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q04917	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q05513	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q8ND90	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q8TEW0	Human	PMID:14676191
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:15590654
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P36897	Human	PMID:15761148
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q05513	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P33151	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q05513	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q8TEW0	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q05513	Human	PMID:17350623
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:19617897
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q9H8V3	Human	PMID:19617897
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q14203	Human	PMID:20719959
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q15154	Human	PMID:20719959
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q05513	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:P41743	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PARD6A	IPI	UniProtKB:Q8TEW0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	Pard6a	IPI	UniProtKB:Q99NH2	Mouse	MGI:MGI:3687818|PMID:10954424
Molecular Function	GO:0005515	protein binding	Pard6a	IPI	UniProtKB:O14641	Mouse	MGI:MGI:3846247|PMID:19379695
Molecular Function	GO:0005515	protein binding	Pard6a	IPI	MGI:MGI:3029152	Mouse	PMID:14685273
Molecular Function	GO:0005515	protein binding	Pard6a	IPI	RGD:70982	Rat	PMID:12610628|RGD:632398
Molecular Function	GO:0005515	protein binding	Pard6a	IPI	RGD:1594738|RGD:70982	Rat	PMID:17728459|RGD:2302549
Molecular Function	GO:0031267	small GTPase binding	Pard6a	IDA		Mouse	MGI:MGI:3687818|PMID:10954424
Cellular Component	GO:0045177	apical part of cell	Pard6a	IDA		Mouse	PMID:21385765
Cellular Component	GO:0016324	apical plasma membrane	pard6a	IDA		Zfish	PMID:18817769
Cellular Component	GO:0044295	axonal growth cone	Pard6a	IDA		Rat	PMID:15090620|RGD:5131992
Cellular Component	GO:0005923	bicellular tight junction	Pard6a	IDA		Mouse	MGI:MGI:3687818|PMID:10954424
Cellular Component	GO:0005938	cell cortex	Pard6a	IDA		Mouse	PMID:15028215
Cellular Component	GO:0034451	centriolar satellite	PARD6A	IDA		Human	PMID:20719959
Cellular Component	GO:0005813	centrosome	PARD6A	IDA		Human	PMID:20719959
Cellular Component	GO:0005737	cytoplasm	Pard6a	IDA		Mouse	PMID:14685273
Cellular Component	GO:0043025	neuronal cell body	Pard6a	IDA		Rat	PMID:15090620|RGD:5131992
Cellular Component	GO:0005634	nucleus	Pard6a	IDA		Mouse	MGI:MGI:3687818|PMID:10954424
Cellular Component	GO:0120157	PAR polarity complex	PARD6A	IPI		Human	PMID:11257119
Cellular Component	GO:0032991	protein-containing complex	Pard6a	IDA		Rat	PMID:18621709|RGD:5131983
Biological Process	GO:0045217	cell-cell junction maintenance	Pard6a	IDA		Mouse	MGI:MGI:3687818|PMID:10954424
Biological Process	GO:0007098	centrosome cycle	PARD6A	IMP		Human	PMID:20719959
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	PARD6A	IDA		Human	PMID:11257119
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Pard6a	IGI	MGI:MGI:97595	Mouse	PMID:24305805
Biological Process	GO:0001841	neural tube formation	pard6a	IGI	ZFIN:ZDB-GENO-081210-1	Zfish	PMID:18817769
Biological Process	GO:1904781	positive regulation of protein localization to centrosome	PARD6A	IMP		Human	PMID:20719959
Biological Process	GO:0050714	positive regulation of protein secretion	Pard6a	IMP		Mouse	MGI:MGI:5924899|PMID:27044754
Biological Process	GO:0060341	regulation of cellular localization	Pard6a	IMP		Rat	PMID:18621709|RGD:5131983

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern