Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARK7
  • Mouse genes Park7
  • Rat genes Park7
  • Zfish genes park7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Park7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	PARK7	HDA		Human	PMID:25468996
Molecular Function	GO:0005507	copper ion binding	PARK7	IDA		Human	PMID:23792957
Molecular Function	GO:1903135	cupric ion binding	PARK7	IDA		Human	PMID:24567322
Molecular Function	GO:1903136	cuprous ion binding	PARK7	IDA		Human	PMID:24144264
Molecular Function	GO:1903136	cuprous ion binding	PARK7	IDA		Human	PMID:24567322
Molecular Function	GO:0019955	cytokine binding	PARK7	IPI	UniProtKB:Q9QZM3	Human	PMID:21097510
Molecular Function	GO:0140297	DNA-binding transcription factor binding	PARK7	IPI	UniProtKB:P23246	Human	PMID:15790595
Molecular Function	GO:0140297	DNA-binding transcription factor binding	PARK7	IPI	UniProtKB:P23246	Human	PMID:16731528
Molecular Function	GO:0019899	enzyme binding	PARK7	IPI	UniProtKB:P07101	Human	PMID:19703902
Molecular Function	GO:0019899	enzyme binding	PARK7	IPI	UniProtKB:P20711	Human	PMID:19703902
Molecular Function	GO:0019899	enzyme binding	PARK7	IPI	UniProtKB:O75489	Human	PMID:19822128
Molecular Function	GO:0019899	enzyme binding	PARK7	IPI	UniProtKB:P03886	Human	PMID:19822128
Molecular Function	GO:0019899	enzyme binding	PARK7	IPI	UniProtKB:P32322	Human	PMID:23743200
Molecular Function	GO:1990422	glyoxalase (glycolic acid-forming) activity	PARK7	IDA		Human	PMID:31653696
Molecular Function	GO:0042802	identical protein binding	PARK7	IPI	UniProtKB:Q99497	Human	PMID:15502874
Molecular Function	GO:0042802	identical protein binding	PARK7	IPI	UniProtKB:Q99497	Human	PMID:15983381
Molecular Function	GO:0042802	identical protein binding	PARK7	IPI	UniProtKB:Q99497	Human	PMID:24947010
Molecular Function	GO:0019900	kinase binding	PARK7	IPI	UniProtKB:Q9BXM7	Human	PMID:19229105
Molecular Function	GO:0036478	L-dopa decarboxylase activator activity	PARK7	IDA		Human	PMID:19703902
Molecular Function	GO:0045340	mercury ion binding	PARK7	IDA		Human	PMID:23792957
Molecular Function	GO:0003729	mRNA binding	PARK7	IDA		Human	PMID:18626009
Molecular Function	GO:0050681	nuclear androgen receptor binding	PARK7	IPI	UniProtKB:P10275	Human	PMID:17510388
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	PARK7	IDA		Human	PMID:24567322
Molecular Function	GO:0019826	oxygen sensor activity	Park7	IMP		Mouse	MGI:MGI:3723371|PMID:17766438
Molecular Function	GO:0008233	peptidase activity	PARK7	IDA		Human	PMID:20304780
Molecular Function	GO:0051920	peroxiredoxin activity	Park7	IMP	MGI:MGI:3514165	Mouse	PMID:17766438
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:O54714	Human	PMID:11477070
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:O75928	Human	PMID:11477070
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q15233	Human	PMID:15790595
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P63165	Human	PMID:15983381
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q99497	Human	PMID:15983381
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9UER7	Human	PMID:15983381
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9BXM7	Human	PMID:16632486
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P10275	Human	PMID:17510388
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q8NFJ9	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:O60260	Human	PMID:19229105
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:O00483	Human	PMID:19822128
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:O94776	Human	PMID:20127688
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q3V3N7	Human	PMID:21097510
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q6GQQ9	Human	PMID:21097510
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q8CHZ9	Human	PMID:21097510
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q13158	Human	PMID:21785459
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P29590	Human	PMID:22683601
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P32322	Human	PMID:23743200
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P40337	Human	PMID:24899725
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P63244	Human	PMID:24947010
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9HD26	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q96FW1	Human	PMID:26752685
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9UMX5	Human	PMID:31536960
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:O14656-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P06241-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:P63010-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q6DN90-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q6ZNA4-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q8IUW3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q8N5S9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q8NFH3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q8NFJ9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q96FW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9BYQ4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9BYZ2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9GZS3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9UBQ0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9UER7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PARK7	IPI	UniProtKB:Q9ULX5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Park7	IPI	UniProtKB:Q9CQ45	Mouse	MGI:MGI:6383486|PMID:31536960
Molecular Function	GO:0005515	protein binding	Park7	IPI	UniProtKB:P68040	Mouse	MGI:MGI:5574514|PMID:24947010
Molecular Function	GO:0005515	protein binding	Park7	IPI	UniProtKB:Q09014	Mouse	MGI:MGI:5825417|PMID:26021615
Molecular Function	GO:0005515	protein binding	Park7	IPI	UniProtKB:Q07813	Mouse	MGI:MGI:5784990|PMID:14752510
Molecular Function	GO:0005515	protein binding	Park7	IPI	RGD:3153	Rat	PMID:16854843|RGD:2313152
Molecular Function	GO:0005515	protein binding	Park7	IPI	UniProtKB:Q6IUR5	Rat	PMID:31536960|RGD:15090841
Molecular Function	GO:0036524	protein deglycase activity	PARK7	IDA		Human	PMID:25416785
Molecular Function	GO:0042803	protein homodimerization activity	PARK7	IDA		Human	PMID:18711745
Molecular Function	GO:0042803	protein homodimerization activity	PARK7	IDA		Human	PMID:24144264
Molecular Function	GO:0042803	protein homodimerization activity	PARK7	IDA		Human	PMID:24567322
Molecular Function	GO:0044877	protein-containing complex binding	PARK7	IDA		Human	PMID:19822128
Molecular Function	GO:0097110	scaffold protein binding	PARK7	IPI	UniProtKB:Q13158	Human	PMID:21785459
Molecular Function	GO:0005102	signaling receptor binding	PARK7	IPI	UniProtKB:O00220	Human	PMID:21785459
Molecular Function	GO:0044388	small protein activating enzyme binding	PARK7	IPI	UniProtKB:Q9UBT2	Human	PMID:15983381
Molecular Function	GO:0016532	superoxide dismutase copper chaperone activity	PARK7	IDA		Human	PMID:24567322
Molecular Function	GO:0003713	transcription coactivator activity	PARK7	IGI	UniProtKB:P23246|UniProtKB:Q15233	Human	PMID:15790595
Molecular Function	GO:0036470	tyrosine 3-monooxygenase activator activity	PARK7	IDA		Human	PMID:19703902
Molecular Function	GO:0044390	ubiquitin-like protein conjugating enzyme binding	PARK7	IPI	UniProtKB:P63279	Human	PMID:15983381
Molecular Function	GO:1990381	ubiquitin-specific protease binding	PARK7	IPI	UniProtKB:B2RUR8	Human	PMID:21097510
Molecular Function	GO:1990381	ubiquitin-specific protease binding	PARK7	IPI	UniProtKB:Q6GQQ9	Human	PMID:21097510
Cellular Component	GO:0005912	adherens junction	PARK7	HDA		Human	PMID:25468996
Cellular Component	GO:0030424	axon	Park7	IDA		Rat	PMID:15673657|RGD:1601078
Cellular Component	GO:0044297	cell body	Park7	IDA		Mouse	MGI:MGI:5574514|PMID:24947010
Cellular Component	GO:0000785	chromatin	PARK7	IDA		Human	PMID:16731528
Cellular Component	GO:0005737	cytoplasm	PARK7	IDA		Human	PMID:12446870
Cellular Component	GO:0005737	cytoplasm	PARK7	IDA		Human	PMID:15983381
Cellular Component	GO:0005737	cytoplasm	PARK7	IDA		Human	PMID:17510388
Cellular Component	GO:0005737	cytoplasm	PARK7	IDA		Human	PMID:18711745
Cellular Component	GO:0005737	cytoplasm	PARK7	IDA		Human	PMID:19822128
Cellular Component	GO:0005829	cytosol	PARK7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PARK7	IDA		Human	PMID:14662519
Cellular Component	GO:0005829	cytosol	PARK7	IDA		Human	PMID:15944198
Cellular Component	GO:0005829	cytosol	PARK7	IDA		Human	PMID:19229105
Cellular Component	GO:0005829	cytosol	PARK7	IMP		Human	PMID:21785459
Cellular Component	GO:0005829	cytosol	PARK7	IDA		Human	PMID:22683601
Cellular Component	GO:0005829	cytosol	Park7	IDA		Mouse	MGI:MGI:5575467|PMID:20969476
Cellular Component	GO:0005829	cytosol	Park7	IDA		Mouse	MGI:MGI:5572878|PMID:15944198
Cellular Component	GO:0005829	cytosol	Park7	IDA		Mouse	PMID:22555455
Cellular Component	GO:0005829	cytosol	Park7	IDA		Rat	PMID:17038803|RGD:1601075
Cellular Component	GO:0005829	cytosol	Park7	IDA		Rat	PMID:19017466|RGD:152025213
Cellular Component	GO:0005783	endoplasmic reticulum	PARK7	IDA		Human	PMID:31536960
Cellular Component	GO:0005783	endoplasmic reticulum	Park7	IDA		Mouse	MGI:MGI:6383486|PMID:31536960
Cellular Component	GO:0005783	endoplasmic reticulum	Park7	IDA		Mouse	PMID:22555455
Cellular Component	GO:0005783	endoplasmic reticulum	Park7	IDA		Rat	PMID:31536960|RGD:15090841
Cellular Component	GO:0070062	extracellular exosome	PARK7	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PARK7	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PARK7	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	PARK7	HDA		Human	PMID:23533145
Cellular Component	GO:0045121	membrane raft	Park7	IDA		Rat	PMID:23847046|RGD:13462068
Cellular Component	GO:0005758	mitochondrial intermembrane space	Park7	IDA		Mouse	MGI:MGI:5572878|PMID:15944198
Cellular Component	GO:0005759	mitochondrial matrix	Park7	IDA		Mouse	MGI:MGI:5572878|PMID:15944198
Cellular Component	GO:0005739	mitochondrion	PARK7	IDA		Human	PMID:15790595
Cellular Component	GO:0005739	mitochondrion	PARK7	IDA		Human	PMID:15944198
Cellular Component	GO:0005739	mitochondrion	PARK7	IDA		Human	PMID:18711745
Cellular Component	GO:0005739	mitochondrion	PARK7	IDA		Human	PMID:19229105
Cellular Component	GO:0005739	mitochondrion	PARK7	IDA		Human	PMID:19822128
Cellular Component	GO:0005739	mitochondrion	PARK7	IMP		Human	PMID:21785459
Cellular Component	GO:0005739	mitochondrion	PARK7	IDA		Human	PMID:23743200
Cellular Component	GO:0005739	mitochondrion	PARK7	IDA		Human	PMID:31536960
Cellular Component	GO:0005739	mitochondrion	Park7	IDA		Mouse	MGI:MGI:5572878|PMID:15944198
Cellular Component	GO:0005739	mitochondrion	Park7	IDA		Mouse	MGI:MGI:6383486|PMID:31536960
Cellular Component	GO:0005739	mitochondrion	Park7	IDA		Mouse	MGI:MGI:5575467|PMID:20969476
Cellular Component	GO:0005739	mitochondrion	Park7	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Park7	IDA		Mouse	PMID:17766438
Cellular Component	GO:0005739	mitochondrion	Park7	IDA		Mouse	PMID:22555455
Cellular Component	GO:0005739	mitochondrion	Park7	IDA		Rat	PMID:31536960|RGD:15090841
Cellular Component	GO:0043005	neuron projection	Park7	IDA		Mouse	MGI:MGI:5574514|PMID:24947010
Cellular Component	GO:0005654	nucleoplasm	PARK7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:11477070
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:12446870
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:14662519
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:15790595
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:15983381
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:18711745
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:19822128
Cellular Component	GO:0005634	nucleus	PARK7	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	PARK7	IDA		Human	PMID:22683601
Cellular Component	GO:0005634	nucleus	Park7	IDA		Mouse	PMID:22555455
Cellular Component	GO:0005634	nucleus	Park7	IDA		Rat	PMID:16246899|RGD:13463457
Cellular Component	GO:0048471	perinuclear region of cytoplasm	PARK7	IDA		Human	PMID:25468996
Cellular Component	GO:0016605	PML body	PARK7	IDA		Human	PMID:22683601
Cellular Component	GO:0098793	presynapse	Park7	IMP	MGI:MGI:3579140	Mouse	MGI:MGI:3578474|PMID:15721235
Cellular Component	GO:0061827	sperm head	Park7	IDA		Rat	PMID:11780923|RGD:13463454
Biological Process	GO:0008344	adult locomotory behavior	Park7	IMP	MGI:MGI:3579140	Mouse	PMID:15721235
Biological Process	GO:0008344	adult locomotory behavior	Park7	IMP	MGI:MGI:3586448	Mouse	PMID:15799973
Biological Process	GO:0007568	aging	Park7	IEP		Rat	PMID:25788877|RGD:13463451
Biological Process	GO:0110095	cellular detoxification of aldehyde	PARK7	IDA		Human	PMID:28993701
Biological Process	GO:0140041	cellular detoxification of methylglyoxal	PARK7	IDA		Human	PMID:28993701
Biological Process	GO:0036471	cellular response to glyoxal	PARK7	IDA		Human	PMID:22523093
Biological Process	GO:0036471	cellular response to glyoxal	Park7	IMP		Mouse	MGI:MGI:5582151|PMID:22523093
Biological Process	GO:0070301	cellular response to hydrogen peroxide	PARK7	IDA		Human	PMID:14749723
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Park7	IMP		Mouse	MGI:MGI:3575338|PMID:15784737
Biological Process	GO:0071456	cellular response to hypoxia	Park7	IEP		Rat	PMID:29069575|RGD:151347449
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Park7	IEP		Rat	PMID:23847046|RGD:13462068
Biological Process	GO:0034599	cellular response to oxidative stress	PARK7	IDA		Human	PMID:15983381
Biological Process	GO:0034599	cellular response to oxidative stress	PARK7	IDA		Human	PMID:19703902
Biological Process	GO:0034599	cellular response to oxidative stress	PARK7	IDA		Human	PMID:20969476
Biological Process	GO:0034599	cellular response to oxidative stress	PARK7	IDA		Human	PMID:22683601
Biological Process	GO:0034599	cellular response to oxidative stress	PARK7	IMP		Human	PMID:24899725
Biological Process	GO:0034599	cellular response to oxidative stress	Park7	IMP		Mouse	MGI:MGI:4889134|PMID:21068725
Biological Process	GO:0034614	cellular response to reactive oxygen species	Park7	IMP	MGI:MGI:3579140	Mouse	PMID:16624565
Biological Process	GO:0070994	detection of oxidative stress	Park7	IMP		Mouse	MGI:MGI:3723371|PMID:17766438
Biological Process	GO:0010273	detoxification of copper ion	PARK7	IMP		Human	PMID:23792957
Biological Process	GO:0010273	detoxification of copper ion	Park7	IMP		Mouse	MGI:MGI:5516159|PMID:23792957
Biological Process	GO:0050787	detoxification of mercury ion	PARK7	IMP		Human	PMID:23792957
Biological Process	GO:0050787	detoxification of mercury ion	Park7	IMP		Mouse	MGI:MGI:5516159|PMID:23792957
Biological Process	GO:0006281	DNA repair	PARK7	IDA		Human	PMID:28596309
Biological Process	GO:0051583	dopamine uptake involved in synaptic transmission	Park7	IMP	MGI:MGI:3579140	Mouse	PMID:15721235
Biological Process	GO:0071542	dopaminergic neuron differentiation	park7	IMP	ZFIN:ZDB-GENO-220818-1	Zfish	PMID:32859696
Biological Process	GO:0042593	glucose homeostasis	Park7	IMP		Mouse	MGI:MGI:5908331|PMID:22611253
Biological Process	GO:0036531	glutathione deglycation	PARK7	IDA		Human	PMID:25416785
Biological Process	GO:0046295	glycolate biosynthetic process	PARK7	IDA		Human	PMID:22523093
Biological Process	GO:0046295	glycolate biosynthetic process	Park7	IDA		Mouse	MGI:MGI:5582151|PMID:22523093
Biological Process	GO:1903189	glyoxal metabolic process	PARK7	IDA		Human	PMID:22523093
Biological Process	GO:1903189	glyoxal metabolic process	Park7	IDA		Mouse	MGI:MGI:5582151|PMID:22523093
Biological Process	GO:0106044	guanine deglycation	PARK7	IDA		Human	PMID:28596309
Biological Process	GO:0106046	guanine deglycation, glyoxal removal	PARK7	IDA		Human	PMID:28596309
Biological Process	GO:0106045	guanine deglycation, methylglyoxal removal	PARK7	IDA		Human	PMID:28596309
Biological Process	GO:0042743	hydrogen peroxide metabolic process	PARK7	IDA		Human	PMID:20969476
Biological Process	GO:0042743	hydrogen peroxide metabolic process	PARK7	IDA		Human	PMID:24567322
Biological Process	GO:0042743	hydrogen peroxide metabolic process	Park7	IMP	MGI:MGI:3514165	Mouse	PMID:17766438
Biological Process	GO:0030073	insulin secretion	Park7	IMP		Mouse	MGI:MGI:5908331|PMID:22611253
Biological Process	GO:0019249	lactate biosynthetic process	PARK7	IDA		Human	PMID:22523093
Biological Process	GO:0060135	maternal process involved in female pregnancy	Park7	IEP		Rat	PMID:17609507|RGD:13463455
Biological Process	GO:0051899	membrane depolarization	Park7	IMP	MGI:MGI:3579140	Mouse	PMID:16624565
Biological Process	GO:0060081	membrane hyperpolarization	Park7	IMP	MGI:MGI:3579140	Mouse	PMID:16624565
Biological Process	GO:0061727	methylglyoxal catabolic process to lactate	PARK7	IDA		Human	PMID:28993701
Biological Process	GO:0009438	methylglyoxal metabolic process	PARK7	IDA		Human	PMID:22523093
Biological Process	GO:0007005	mitochondrion organization	Park7	IMP		Mouse	MGI:MGI:4437348|PMID:20186336
Biological Process	GO:0043066	negative regulation of apoptotic process	PARK7	IDA		Human	PMID:22523093
Biological Process	GO:0043066	negative regulation of apoptotic process	Park7	IMP		Mouse	MGI:MGI:5582151|PMID:22523093
Biological Process	GO:0060548	negative regulation of cell death	PARK7	IDA		Human	PMID:14749723
Biological Process	GO:0060548	negative regulation of cell death	Park7	IMP		Mouse	MGI:MGI:3575338|PMID:15784737
Biological Process	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	PARK7	IMP		Human	PMID:21785459
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	PARK7	IGI	UniProtKB:Q99LX0	Human	PMID:14652021
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Park7	IMP		Mouse	MGI:MGI:5613479|PMID:14652021
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	PARK7	IMP		Human	PMID:21785459
Biological Process	GO:0010629	negative regulation of gene expression	PARK7	IDA		Human	PMID:22683601
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	PARK7	IMP		Human	PMID:22492997
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	PARK7	IMP		Human	PMID:23743200
Biological Process	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	PARK7	IDA		Human	PMID:15983381
Biological Process	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	PARK7	IDA		Human	PMID:24947010
Biological Process	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	Park7	IMP		Mouse	MGI:MGI:5574514|PMID:24947010
Biological Process	GO:1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	PARK7	IGI	UniProtKB:Q99LX0	Human	PMID:14652021
Biological Process	GO:1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	Park7	IMP		Mouse	MGI:MGI:5613479|PMID:14652021
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	PARK7	IDA		Human	PMID:22511790
Biological Process	GO:1901215	negative regulation of neuron death	PARK7	IDA		Human	PMID:22683601
Biological Process	GO:1901215	negative regulation of neuron death	Park7	IMP		Rat	PMID:20698836|RGD:13463453
Biological Process	GO:1905259	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	PARK7	IDA		Human	PMID:14752510
Biological Process	GO:1904782	negative regulation of NMDA glutamate receptor activity	Park7	IMP		Rat	PMID:20698836|RGD:13463453
Biological Process	GO:1903202	negative regulation of oxidative stress-induced cell death	PARK7	IDA		Human	PMID:16632486
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	Park7	IMP		Mouse	MGI:MGI:5575789|PMID:24899725
Biological Process	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	PARK7	IDA		Human	PMID:15790595
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	PARK7	IDA		Human	PMID:17015834
Biological Process	GO:1901984	negative regulation of protein acetylation	PARK7	IDA		Human	PMID:22683601
Biological Process	GO:0032091	negative regulation of protein binding	PARK7	IDA		Human	PMID:11477070
Biological Process	GO:0032091	negative regulation of protein binding	PARK7	IGI	UniProtKB:Q99683|UniProtKB:Q9UER7	Human	PMID:15983381
Biological Process	GO:0032091	negative regulation of protein binding	PARK7	IDA		Human	PMID:16731528
Biological Process	GO:0032091	negative regulation of protein binding	PARK7	IDA		Human	PMID:17015834
Biological Process	GO:0032091	negative regulation of protein binding	PARK7	IMP		Human	PMID:21785459
Biological Process	GO:0032091	negative regulation of protein binding	PARK7	IDA		Human	PMID:24899725
Biological Process	GO:0042177	negative regulation of protein catabolic process	Park7	IMP		Mouse	MGI:MGI:5575789|PMID:24899725
Biological Process	GO:0046826	negative regulation of protein export from nucleus	PARK7	IGI	UniProtKB:Q99683|UniProtKB:Q9UER7	Human	PMID:15983381
Biological Process	GO:1903094	negative regulation of protein K48-linked deubiquitination	PARK7	IDA		Human	PMID:21097510
Biological Process	GO:0006469	negative regulation of protein kinase activity	PARK7	IGI	UniProtKB:Q99683|UniProtKB:Q9UER7	Human	PMID:15983381
Biological Process	GO:0001933	negative regulation of protein phosphorylation	PARK7	IGI	UniProtKB:Q99683|UniProtKB:Q9UER7	Human	PMID:15983381
Biological Process	GO:0033234	negative regulation of protein sumoylation	PARK7	IDA		Human	PMID:16731528
Biological Process	GO:0031397	negative regulation of protein ubiquitination	PARK7	IDA		Human	PMID:17015834
Biological Process	GO:0031397	negative regulation of protein ubiquitination	PARK7	IDA		Human	PMID:24899725
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Park7	IMP		Mouse	MGI:MGI:5575789|PMID:24899725
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Park7	IMP		Mouse	MGI:MGI:5908331|PMID:22611253
Biological Process	GO:0014912	negative regulation of smooth muscle cell migration	Park7	IDA		Rat	PMID:29069575|RGD:151347449
Biological Process	GO:1903122	negative regulation of TRAIL-activated apoptotic signaling pathway	PARK7	IMP		Human	PMID:21785459
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	PARK7	IDA		Human	PMID:24899725
Biological Process	GO:2000157	negative regulation of ubiquitin-specific protease activity	PARK7	IDA		Human	PMID:21097510
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	Park7	IDA		Rat	PMID:29069575|RGD:151347449
Biological Process	GO:0036527	peptidyl-arginine deglycation	PARK7	IDA		Human	PMID:25416785
Biological Process	GO:0036527	peptidyl-arginine deglycation	PARK7	IMP		Human	PMID:30150385
Biological Process	GO:0036526	peptidyl-cysteine deglycation	PARK7	IDA		Human	PMID:25416785
Biological Process	GO:0036528	peptidyl-lysine deglycation	PARK7	IDA		Human	PMID:25416785
Biological Process	GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	Park7	IMP		Mouse	MGI:MGI:5825417|PMID:26021615
Biological Process	GO:2000825	positive regulation of androgen receptor activity	PARK7	IMP		Human	PMID:17510388
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	PARK7	IMP		Human	PMID:17015834
Biological Process	GO:1903181	positive regulation of dopamine biosynthetic process	PARK7	IDA		Human	PMID:19703902
Biological Process	GO:1905516	positive regulation of fertilization	Park7	IMP		Rat	PMID:11780923|RGD:13463454
Biological Process	GO:0010628	positive regulation of gene expression	Park7	IMP		Mouse	MGI:MGI:5425173|PMID:22492997
Biological Process	GO:0032757	positive regulation of interleukin-8 production	PARK7	IDA		Human	PMID:21097510
Biological Process	GO:1903197	positive regulation of L-dopa biosynthetic process	PARK7	IMP		Human	PMID:16731528
Biological Process	GO:1903200	positive regulation of L-dopa decarboxylase activity	PARK7	IDA		Human	PMID:19703902
Biological Process	GO:1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	PARK7	IMP		Human	PMID:19822128
Biological Process	GO:1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	Park7	IMP		Mouse	MGI:MGI:5582165|PMID:19822128
Biological Process	GO:0033864	positive regulation of NAD(P)H oxidase activity	Park7	IMP		Mouse	MGI:MGI:5825417|PMID:26021615
Biological Process	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	Park7	IMP		Mouse	MGI:MGI:4889134|PMID:21068725
Biological Process	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Park7	IMP		Mouse	PMID:22555455
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	PARK7	IMP		Human	PMID:22492997
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	PARK7	IDA		Human	PMID:21097510
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	PARK7	IMP		Human	PMID:22492997
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	PARK7	IDA		Human	PMID:24947010
Biological Process	GO:1903168	positive regulation of pyrroline-5-carboxylate reductase activity	PARK7	IDA		Human	PMID:23743200
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	Park7	IDA		Mouse	PMID:22555455
Biological Process	GO:1901671	positive regulation of superoxide dismutase activity	PARK7	IDA		Human	PMID:24567322
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PARK7	IGI	UniProtKB:P23246|UniProtKB:Q15233	Human	PMID:15790595
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PARK7	IMP		Human	PMID:16731528
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PARK7	IGI	UniProtKB:Q16236	Human	PMID:17015834
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PARK7	IMP		Human	PMID:19703902
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PARK7	IDA		Human	PMID:21097510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PARK7	IMP		Human	PMID:22492997
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Park7	IMP		Mouse	MGI:MGI:5574296|PMID:21097510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Park7	IMP		Mouse	MGI:MGI:4943400|PMID:17015834
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	PARK7	IMP		Human	PMID:22492997
Biological Process	GO:1903178	positive regulation of tyrosine 3-monooxygenase activity	PARK7	IDA		Human	PMID:19703902
Biological Process	GO:0036529	protein deglycation, glyoxal removal	PARK7	IDA		Human	PMID:25416785
Biological Process	GO:0036530	protein deglycation, methylglyoxal removal	PARK7	IDA		Human	PMID:25416785
Biological Process	GO:0036530	protein deglycation, methylglyoxal removal	PARK7	IMP		Human	PMID:30150385
Biological Process	GO:0006517	protein deglycosylation	PARK7	IDA		Human	PMID:25416785
Biological Process	GO:0006517	protein deglycosylation	PARK7	IMP		Human	PMID:26995087
Biological Process	GO:0006517	protein deglycosylation	PARK7	IMP		Human	PMID:30894531
Biological Process	GO:0050821	protein stabilization	PARK7	IMP		Human	PMID:17015834
Biological Process	GO:0050821	protein stabilization	PARK7	IMP		Human	PMID:19229105
Biological Process	GO:0050821	protein stabilization	PARK7	IDA		Human	PMID:24947010
Biological Process	GO:0050821	protein stabilization	Park7	IMP		Mouse	MGI:MGI:3837120|PMID:19229105
Biological Process	GO:0050821	protein stabilization	Park7	IMP		Mouse	MGI:MGI:4943400|PMID:17015834
Biological Process	GO:0060765	regulation of androgen receptor signaling pathway	PARK7	IDA		Human	PMID:11477070
Biological Process	GO:0050727	regulation of inflammatory response	Park7	IMP		Mouse	MGI:MGI:4943657|PMID:19276172
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	PARK7	IMP		Human	PMID:23743200
Biological Process	GO:0043523	regulation of neuron apoptotic process	PARK7	IDA		Human	PMID:18711745
Biological Process	GO:0043523	regulation of neuron apoptotic process	PARK7	IDA		Human	PMID:20304780
Biological Process	GO:0042542	response to hydrogen peroxide	Park7	IMP	MGI:MGI:3576227	Mouse	PMID:15784737
Biological Process	GO:0042542	response to hydrogen peroxide	Park7	IDA		Mouse	PMID:15784737
Biological Process	GO:0006979	response to oxidative stress	Park7	IMP		Rat	PMID:16227205|RGD:1601077
Biological Process	GO:0006979	response to oxidative stress	park7	IMP	ZFIN:ZDB-MRPHLNO-090320-6	Zfish	PMID:19243613
Biological Process	GO:0009410	response to xenobiotic stimulus	Park7	IEP		Rat	PMID:17038803|RGD:1601075
Biological Process	GO:0007283	spermatogenesis	Park7	IEP		Rat	PMID:11780923|RGD:13463454
Biological Process	GO:0036269	swimming behavior	park7	IMP	ZFIN:ZDB-GENO-220818-1	Zfish	PMID:32859696
Biological Process	GO:0001963	synaptic transmission, dopaminergic	Park7	IMP	MGI:MGI:3586448	Mouse	PMID:15799973

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern