Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARP1
  • Mouse genes Parp1
  • Rat genes Parp1
  • Zfish genes parp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Parp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	PARP1	IDA		Human	PMID:30675909
Molecular Function	GO:0003682	chromatin binding	PARP1	IDA		Human	PMID:34874266
Molecular Function	GO:0003682	chromatin binding	PARP1	IDA		Human	PMID:35013556
Molecular Function	GO:0003682	chromatin binding	Parp1	IDA		Mouse	PMID:24449909
Molecular Function	GO:0003684	damaged DNA binding	PARP1	IDA		Human	PMID:22683995
Molecular Function	GO:0003684	damaged DNA binding	PARP1	IDA		Human	PMID:26626479
Molecular Function	GO:0003684	damaged DNA binding	PARP1	IDA		Human	PMID:26626480
Molecular Function	GO:0003684	damaged DNA binding	PARP1	IDA		Human	PMID:27568560
Molecular Function	GO:0003684	damaged DNA binding	PARP1	IDA		Human	PMID:30675909
Molecular Function	GO:0003684	damaged DNA binding	PARP1	IDA		Human	PMID:32241924
Molecular Function	GO:0003684	damaged DNA binding	PARP1	IDA		Human	PMID:32358582
Molecular Function	GO:0003677	DNA binding	PARP1	IDA		Human	PMID:21233213
Molecular Function	GO:0008047	enzyme activator activity	PARP1	IDA		Human	PMID:27568560
Molecular Function	GO:0008047	enzyme activator activity	PARP1	IDA		Human	PMID:32028527
Molecular Function	GO:0019899	enzyme binding	PARP1	IPI	UniProtKB:Q96EB6	Human	PMID:23382074
Molecular Function	GO:0019899	enzyme binding	Parp1	IPI	UniProtKB:A0A0G2JZ79	Rat	PMID:19470756|RGD:8553699
Molecular Function	GO:0042826	histone deacetylase binding	Parp1	IPI	RGD:1308542	Rat	PMID:19470756|RGD:8553699
Molecular Function	GO:0042802	identical protein binding	PARP1	IPI	UniProtKB:P09874	Human	PMID:14734561
Molecular Function	GO:0042802	identical protein binding	PARP1	IPI	UniProtKB:P09874	Human	PMID:23481255
Molecular Function	GO:0051287	NAD binding	Parp1	IDA		Rat	PMID:15857403|RGD:1601082
Molecular Function	GO:0051287	NAD binding	Parp1	IDA		Rat	PMID:16302026|RGD:1601079
Molecular Function	GO:0140294	NAD DNA ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:27471034
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:16107709
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:17396150
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:18055453
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:19470756
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:19764761
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:20388712
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IMP		Human	PMID:22504299
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:23275542
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:26626479
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:26626480
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:28190768
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:30104678
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:32028527
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:32241924
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:32358582
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:33186521
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:33683197
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34732825
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34795260
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:35219381
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:7852410
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	Parp1	IDA		Mouse	PMID:28991266
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	Parp1	IDA		Mouse	PMID:22736760
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	Parp1	IMP		Mouse	PMID:24449909
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	Parp1	IDA		Rat	PMID:15857403|RGD:1601082
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	Parp1	IDA		Rat	PMID:16302026|RGD:1601079
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:19764761
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:25043379
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:35460603
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	Parp1	IDA		Mouse	MGI:MGI:6468977|PMID:32822587
Molecular Function	GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	Parp1	IDA		Mouse	PMID:32822587
Molecular Function	GO:0140816	NAD+-histone H2BS6 serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34874266
Molecular Function	GO:0140817	NAD+-histone H3S10 serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34874266
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:19764761
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:25043379
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:25533949
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:26344098
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:28190768
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:31796734
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:32028527
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:33186521
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34049076
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34102106
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34625544
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:7852410
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	Parp1	IDA		Mouse	PMID:24550317
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:19764761
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:27256882
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	Parp1	IMP		Mouse	MGI:MGI:7286108|PMID:35460603
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	Parp1	IDA		Mouse	MGI:MGI:6468977|PMID:32822587
Molecular Function	GO:0140815	NAD+-protein-histidine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:35393539
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:28190768
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:29234005
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:32028527
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:33186521
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:33412112
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:33589610
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:33683197
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34210965
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34732825
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34795260
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:34874266
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:35393539
Molecular Function	GO:0140808	NAD+-protein-tyrosine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:29954836
Molecular Function	GO:0140808	NAD+-protein-tyrosine ADP-ribosyltransferase activity	PARP1	IDA		Human	PMID:30257210
Molecular Function	GO:0030331	nuclear estrogen receptor binding	Parp1	IPI	RGD:2581	Rat	PMID:23493398|RGD:10413906
Molecular Function	GO:0031491	nucleosome binding	PARP1	IDA		Human	PMID:15607977
Molecular Function	GO:0031491	nucleosome binding	PARP1	IDA		Human	PMID:31848352
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9HAN9	Human	PMID:11248244
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q14191	Human	PMID:14596914
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P04637	Human	PMID:14627987
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q01094	Human	PMID:14627987
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q14191	Human	PMID:14734561
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P04637	Human	PMID:15044383
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P18887	Human	PMID:15044383
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q7Z2E3	Human	PMID:15044383
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q7Z2E3	Human	PMID:15555565
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q03468	Human	PMID:16107709
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P49715	Human	PMID:16490787
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P42574	Human	PMID:17167422
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q8IW19	Human	PMID:17396150
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q8IW19	Human	PMID:18172500
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q96EP1	Human	PMID:18172500
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P18887	Human	PMID:18971944
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q5TUF1	Human	PMID:19661379
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q86WJ1	Human	PMID:19661379
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q86WJ1-1	Human	PMID:19666485
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q14684-1	Human	PMID:19710015
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P0CG48	Human	PMID:19779455
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P63165	Human	PMID:19779455
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q8N2W9	Human	PMID:19779455
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9Y6F1	Human	PMID:20064938
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q8IW19	Human	PMID:20098424
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q01094	Human	PMID:20133863
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q15397	Human	PMID:21266351
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9H4L7	Human	PMID:21549307
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P11308	Human	PMID:21575865
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:O95863	Human	PMID:21577210
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q02085	Human	PMID:21577210
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9NTX7	Human	PMID:21799911
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P12956,UniProtKB:P13010	Human	PMID:22504299
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P12956,UniProtKB:P13010,UniProtKB:P78527	Human	PMID:22504299
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P23381	Human	PMID:22504299
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P23381,UniProtKB:P78527	Human	PMID:22504299
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q2M1K9	Human	PMID:22863007
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q8IXQ6	Human	PMID:23230272
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P46063	Human	PMID:23396353
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9Y530	Human	PMID:23481255
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q70YC5	Human	PMID:23966166
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P18887	Human	PMID:24778456
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P54577	Human	PMID:25533949
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q13007	Human	PMID:25640309
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P12956	Human	PMID:25749521
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P78527	Human	PMID:25749521
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9C0C2	Human	PMID:25749521
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9UNS1	Human	PMID:26344098
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9NWY4	Human	PMID:27067600
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9H967	Human	PMID:27248496
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P26358	Human	PMID:27728808
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9NWY4	Human	PMID:28190768
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q8IW19	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P09429	Human	PMID:29721183
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q8C6L5	Human	PMID:30356214
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q9UNS1	Human	PMID:30356214
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q587J8	Human	PMID:31609975
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:O75531	Human	PMID:31796734
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:Q86X55	Human	PMID:33412112
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P18887	Human	PMID:34102106
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P0DW81	Human	PMID:35219381
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P42574	Human	PMID:7596430
Molecular Function	GO:0005515	protein binding	PARP1	IPI	UniProtKB:P09884	Human	PMID:9518481
Molecular Function	GO:0005515	protein binding	Parp1	IPI	UniProtKB:P20263	Mouse	MGI:MGI:4943831|PMID:20362542
Molecular Function	GO:0005515	protein binding	Parp1	IPI	UniProtKB:P70288|UniProtKB:Q3TKT4	Mouse	MGI:MGI:4819442|PMID:20596014
Molecular Function	GO:0005515	protein binding	Parp1	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:4881368|PMID:20832105
Molecular Function	GO:0005515	protein binding	Parp1	IPI	UniProtKB:P70677|UniProtKB:P97864	Mouse	MGI:MGI:5306569|PMID:19759058
Molecular Function	GO:0005515	protein binding	Parp1	IPI	UniProtKB:P03087	Mouse	MGI:MGI:5512961|PMID:16979186
Molecular Function	GO:0005515	protein binding	Parp1	IPI	UniProtKB:Q9CWU5	Mouse	MGI:MGI:6716962|PMID:25936915
Molecular Function	GO:0005515	protein binding	Parp1	IPI	PR:Q3U2S4	Mouse	PMID:25470037
Molecular Function	GO:0005515	protein binding	Parp1	IPI	PR:Q91YK2	Mouse	PMID:19710015
Molecular Function	GO:0005515	protein binding	Parp1	IPI	PR:P18608	Mouse	PMID:22736760
Molecular Function	GO:0005515	protein binding	Parp1	IPI	UniProtKB:P51179	Rat	PMID:25625556|RGD:10054073
Molecular Function	GO:0042803	protein homodimerization activity	PARP1	IDA		Human	PMID:22683995
Molecular Function	GO:0019901	protein kinase binding	PARP1	IPI	UniProtKB:P42681	Human	PMID:17177976
Molecular Function	GO:0070412	R-SMAD binding	Parp1	IPI	UniProtKB:P84025	Rat	PMID:22073128|RGD:8554355
Molecular Function	GO:0003723	RNA binding	PARP1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PARP1	HDA		Human	PMID:22681889
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	PARP1	IPI	UniProtKB:P22415	Human	PMID:19303849
Molecular Function	GO:0046332	SMAD binding	Parp1	IPI	RGD:3032	Rat	PMID:22073128|RGD:8554355
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Parp1	IPI	RGD:1306482	Rat	PMID:24842055|RGD:13524867
Molecular Function	GO:0008270	zinc ion binding	PARP1	IDA		Human	PMID:18055453
Molecular Function	GO:0008270	zinc ion binding	PARP1	IDA		Human	PMID:21233213
Cellular Component	GO:0000785	chromatin	PARP1	IDA		Human	PMID:15607977
Cellular Component	GO:0000785	chromatin	PARP1	IDA		Human	PMID:30675909
Cellular Component	GO:0000785	chromatin	PARP1	IDA		Human	PMID:34874266
Cellular Component	GO:0000785	chromatin	PARP1	IDA		Human	PMID:35013556
Cellular Component	GO:0000785	chromatin	Parp1	IDA		Mouse	PMID:20647423
Cellular Component	GO:0000781	chromosome, telomeric region	PARP1	HDA		Human	PMID:19135898
Cellular Component	GO:0005737	cytoplasm	Parp1	IDA		Mouse	MGI:MGI:4353867|PMID:19470756
Cellular Component	GO:0005737	cytoplasm	Parp1	IDA		Rat	PMID:24842055|RGD:13524867
Cellular Component	GO:0005829	cytosol	PARP1	IDA		Human	PMID:35460603
Cellular Component	GO:0016020	membrane	PARP1	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	PARP1	IDA		Human	PMID:25378300
Cellular Component	GO:0016604	nuclear body	PARP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005635	nuclear envelope	PARP1	IDA		Human	PMID:9518481
Cellular Component	GO:0043596	nuclear replication fork	PARP1	IDA		Human	PMID:33412112
Cellular Component	GO:0005730	nucleolus	PARP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	PARP1	IDA		Human	PMID:16107709
Cellular Component	GO:0005730	nucleolus	PARP1	IDA		Human	PMID:9518481
Cellular Component	GO:0005730	nucleolus	Parp1	IDA		Mouse	PMID:15615785
Cellular Component	GO:0005654	nucleoplasm	PARP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	Parp1	IDA		Mouse	PMID:15615785
Cellular Component	GO:0005634	nucleus	PARP1	IDA		Human	PMID:22464733
Cellular Component	GO:0005634	nucleus	PARP1	IDA		Human	PMID:27256882
Cellular Component	GO:0005634	nucleus	PARP1	IDA		Human	PMID:34102106
Cellular Component	GO:0005634	nucleus	PARP1	IDA		Human	PMID:35393539
Cellular Component	GO:0005634	nucleus	PARP1	IDA		Human	PMID:35460603
Cellular Component	GO:0005634	nucleus	PARP1	IDA		Human	PMID:17177976
Cellular Component	GO:0005634	nucleus	PARP1	IDA		Human	PMID:22504299
Cellular Component	GO:0005634	nucleus	Parp1	IDA		Mouse	MGI:MGI:6716962|PMID:25936915
Cellular Component	GO:0005634	nucleus	Parp1	IDA		Mouse	MGI:MGI:4353867|PMID:19470756
Cellular Component	GO:0005634	nucleus	Parp1	IDA		Mouse	PMID:28991266
Cellular Component	GO:0005634	nucleus	Parp1	IDA		Rat	PMID:15857403|RGD:1601082
Cellular Component	GO:0005634	nucleus	Parp1	IDA		Rat	PMID:16093393|RGD:1601081
Cellular Component	GO:0005634	nucleus	Parp1	IDA		Rat	PMID:16302026|RGD:1601079
Cellular Component	GO:0005634	nucleus	Parp1	IDA		Rat	PMID:22073128|RGD:8554355
Cellular Component	GO:0032991	protein-containing complex	PARP1	IDA		Human	PMID:22504299
Cellular Component	GO:0032991	protein-containing complex	PARP1	IDA		Human	PMID:25378300
Cellular Component	GO:0032991	protein-containing complex	Parp1	IDA		Mouse	PMID:19796622
Cellular Component	GO:0032993	protein-DNA complex	PARP1	IDA		Human	PMID:22504299
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:22683995
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:26626479
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:26626480
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:30104678
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:30675909
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:31796734
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:32028527
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:32241924
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:32358582
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:33186521
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:34795260
Cellular Component	GO:0090734	site of DNA damage	PARP1	IDA		Human	PMID:34874266
Cellular Component	GO:0090734	site of DNA damage	PARP1	IMP		Human	PMID:27248496
Cellular Component	GO:0090734	site of DNA damage	Parp1	IDA		Mouse	PMID:22736760
Cellular Component	GO:0035861	site of double-strand break	PARP1	IDA		Human	PMID:29234005
Cellular Component	GO:0035861	site of double-strand break	PARP1	IDA		Human	PMID:26344098
Cellular Component	GO:0035861	site of double-strand break	PARP1	IDA		Human	PMID:27568560
Cellular Component	GO:0035861	site of double-strand break	PARP1	IDA		Human	PMID:30356214
Cellular Component	GO:0005667	transcription regulator complex	PARP1	IDA		Human	PMID:19303849
Biological Process	GO:0006915	apoptotic process	PARP1	IDA		Human	PMID:15565177
Biological Process	GO:1990966	ATP generation from poly-ADP-D-ribose	PARP1	IDA		Human	PMID:27257257
Biological Process	GO:0006284	base-excision repair	Parp1	IMP		Mouse	PMID:11948190
Biological Process	GO:0048148	behavioral response to cocaine	Parp1	IMP		Mouse	PMID:24449909
Biological Process	GO:0016051	carbohydrate biosynthetic process	Parp1	IDA		Rat	PMID:15857403|RGD:1601082
Biological Process	GO:1904646	cellular response to amyloid-beta	Parp1	IMP		Rat	PMID:21616968|RGD:10413888
Biological Process	GO:0032869	cellular response to insulin stimulus	PARP1	IDA		Human	PMID:19303849
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Parp1	IDA		Rat	PMID:16093393|RGD:1601081
Biological Process	GO:0034599	cellular response to oxidative stress	PARP1	IMP		Human	PMID:25378300
Biological Process	GO:0071451	cellular response to superoxide	Parp1	IDA		Mouse	PMID:24191052
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:0034644	cellular response to UV	PARP1	IMP		Human	PMID:24289924
Biological Process	GO:0071294	cellular response to zinc ion	Parp1	IEP		Rat	PMID:23582235|RGD:10414068
Biological Process	GO:0046697	decidualization	Parp1	IMP		Mouse	MGI:MGI:6771550|PMID:34580230
Biological Process	GO:0030592	DNA ADP-ribosylation	PARP1	IDA		Human	PMID:27471034
Biological Process	GO:0006974	DNA damage response	PARP1	IMP		Human	PMID:24550317
Biological Process	GO:0006974	DNA damage response	PARP1	IDA		Human	PMID:22683995
Biological Process	GO:0006974	DNA damage response	PARP1	IMP		Human	PMID:24289924
Biological Process	GO:0006974	DNA damage response	PARP1	IMP		Human	PMID:27067600
Biological Process	GO:0006974	DNA damage response	PARP1	IMP		Human	PMID:27248496
Biological Process	GO:0006974	DNA damage response	PARP1	IDA		Human	PMID:32358582
Biological Process	GO:0006974	DNA damage response	PARP1	IDA		Human	PMID:35013556
Biological Process	GO:0006974	DNA damage response	PARP1	IDA		Human	PMID:35393539
Biological Process	GO:0006974	DNA damage response	Parp1	IDA		Rat	PMID:15857403|RGD:1601082
Biological Process	GO:0006259	DNA metabolic process	Parp1	IMP		Mouse	PMID:11756244
Biological Process	GO:0006259	DNA metabolic process	Parp1	IMP	MGI:MGI:1857862	Mouse	PMID:12707040
Biological Process	GO:0006281	DNA repair	PARP1	IDA		Human	PMID:30104678
Biological Process	GO:0006281	DNA repair	PARP1	IDA		Human	PMID:30675909
Biological Process	GO:0006281	DNA repair	PARP1	IDA		Human	PMID:31796734
Biological Process	GO:0006281	DNA repair	PARP1	IDA		Human	PMID:32028527
Biological Process	GO:0006281	DNA repair	PARP1	IDA		Human	PMID:33186521
Biological Process	GO:0006281	DNA repair	PARP1	IDA		Human	PMID:34874266
Biological Process	GO:0006281	DNA repair	Parp1	IDA		Mouse	PMID:22736760
Biological Process	GO:0006302	double-strand break repair	PARP1	IMP		Human	PMID:23230272
Biological Process	GO:0006302	double-strand break repair	PARP1	IDA		Human	PMID:27568560
Biological Process	GO:0006302	double-strand break repair	PARP1	IDA		Human	PMID:28190768
Biological Process	GO:0006302	double-strand break repair	PARP1	IDA		Human	PMID:32028527
Biological Process	GO:0006302	double-strand break repair	Parp1	IGI	MGI:MGI:1891258	Mouse	PMID:21270334
Biological Process	GO:0032042	mitochondrial DNA metabolic process	PARP1	IMP		Human	PMID:25378300
Biological Process	GO:0043504	mitochondrial DNA repair	PARP1	IMP		Human	PMID:25378300
Biological Process	GO:0007005	mitochondrion organization	PARP1	IMP		Human	PMID:25378300
Biological Process	GO:0007005	mitochondrion organization	Parp1	IMP		Mouse	PMID:25378300
Biological Process	GO:1904178	negative regulation of adipose tissue development	Parp1	IDA		Mouse	PMID:32822587
Biological Process	GO:2001170	negative regulation of ATP biosynthetic process	PARP1	IMP		Human	PMID:24289924
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Parp1	IDA		Mouse	PMID:32822587
Biological Process	GO:0045824	negative regulation of innate immune response	PARP1	IMP		Human	PMID:32844745
Biological Process	GO:0045824	negative regulation of innate immune response	PARP1	IDA		Human	PMID:35460603
Biological Process	GO:0045824	negative regulation of innate immune response	Parp1	IMP		Mouse	MGI:MGI:7286108|PMID:35460603
Biological Process	GO:0032700	negative regulation of interleukin-17 production	Parp1	IMP		Mouse	PMID:25470037
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	Parp1	IMP		Mouse	MGI:MGI:5705431|PMID:26586427
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PARP1	IDA		Human	PMID:15607977
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PARP1	IDA		Human	PMID:22464733
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	PARP1	IDA		Human	PMID:35393539
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	Parp1	IMP		Rat	PMID:25625556|RGD:10054073
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	PARP1	IDA		Human	PMID:27256882
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	PARP1	IDA		Human	PMID:26344098
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	PARP1	IDA		Human	PMID:30356214
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	PARP1	IDA		Human	PMID:22464733
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	Parp1	IMP		Rat	PMID:23493398|RGD:10413906
Biological Process	GO:0051901	positive regulation of mitochondrial depolarization	Parp1	IMP		Rat	PMID:21616968|RGD:10413888
Biological Process	GO:1904762	positive regulation of myofibroblast differentiation	Parp1	IMP		Rat	PMID:23260200|RGD:10413908
Biological Process	GO:0060545	positive regulation of necroptotic process	Parp1	IDA		Mouse	MGI:MGI:2182480|PMID:12114629
Biological Process	GO:0060545	positive regulation of necroptotic process	Parp1	IDA		Mouse	MGI:MGI:3695559|PMID:17116882
Biological Process	GO:1901216	positive regulation of neuron death	Parp1	IMP		Rat	PMID:21616968|RGD:10413888
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:1903518	positive regulation of single strand break repair	PARP1	IGI	UniProtKB:P18887	Human	PMID:28002403
Biological Process	GO:1903518	positive regulation of single strand break repair	Parp1	IGI	UniProtKB:Q60596	Mouse	MGI:MGI:5902647|PMID:28002403
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PARP1	IDA		Human	PMID:11112786
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP1	IDA		Human	PMID:15607977
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP1	IDA		Human	PMID:20388712
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP1	IDA		Human	PMID:29234005
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP1	IDA		Human	PMID:30675909
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP1	IDA		Human	PMID:32358582
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP1	IDA		Human	PMID:34210965
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP1	IDA		Human	PMID:34625544
Biological Process	GO:0016540	protein autoprocessing	Parp1	IDA		Rat	PMID:16093393|RGD:1601081
Biological Process	GO:0071168	protein localization to chromatin	PARP1	IDA		Human	PMID:34874266
Biological Process	GO:0036211	protein modification process	PARP1	IMP		Human	PMID:25378300
Biological Process	GO:0036211	protein modification process	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:0070212	protein poly-ADP-ribosylation	PARP1	IDA		Human	PMID:15674325
Biological Process	GO:0070212	protein poly-ADP-ribosylation	PARP1	IDA		Human	PMID:19470756
Biological Process	GO:0070212	protein poly-ADP-ribosylation	PARP1	IDA		Human	PMID:25043379
Biological Process	GO:0070212	protein poly-ADP-ribosylation	PARP1	IDA		Human	PMID:28190768
Biological Process	GO:0070212	protein poly-ADP-ribosylation	PARP1	IDA		Human	PMID:33186521
Biological Process	GO:0070212	protein poly-ADP-ribosylation	Parp1	IDA		Mouse	PMID:28991266
Biological Process	GO:0070212	protein poly-ADP-ribosylation	Parp1	IDA		Mouse	PMID:24449909
Biological Process	GO:0070212	protein poly-ADP-ribosylation	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:1905051	regulation of base-excision repair	PARP1	IDA		Human	PMID:34102106
Biological Process	GO:0050790	regulation of catalytic activity	PARP1	IDA		Human	PMID:25749521
Biological Process	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	Parp1	IMP		Mouse	MGI:MGI:6874638|PMID:34798058
Biological Process	GO:0044030	regulation of DNA methylation	Parp1	IMP		Rat	PMID:23260200|RGD:10413908
Biological Process	GO:0040009	regulation of growth rate	Parp1	IMP	MGI:MGI:1857862	Mouse	PMID:12707040
Biological Process	GO:1903376	regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Parp1	IMP		Rat	PMID:17347665|RGD:10414071
Biological Process	GO:0032880	regulation of protein localization	PARP1	IMP		Human	PMID:24550317
Biological Process	GO:1903516	regulation of single strand break repair	Parp1	IMP		Mouse	PMID:25378300
Biological Process	GO:0010990	regulation of SMAD protein complex assembly	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:0071932	replication fork reversal	PARP1	IDA		Human	PMID:33412112
Biological Process	GO:1904044	response to aldosterone	Parp1	IEP		Rat	PMID:14994994|RGD:10414067
Biological Process	GO:0010332	response to gamma radiation	Parp1	IEP		Rat	PMID:14994994|RGD:10414067
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:0000723	telomere maintenance	Parp1	IMP	MGI:MGI:1857862	Mouse	PMID:12707040
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Parp1	IMP		Rat	PMID:22073128|RGD:8554355
Biological Process	GO:0050882	voluntary musculoskeletal movement	Parp1	IGI	UniProtKB:Q60596	Mouse	MGI:MGI:5902647|PMID:28002403

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern