Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARP10
  • Mouse genes Parp10
  • Rat genes Parp10
  • Zfish genes parp10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Parp10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	PARP10	IPI	UniProtKB:P01106	Human	PMID:15674325
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	PARP10	IMP		Human	PMID:23575687
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP10	IMP		Human	PMID:23473667
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP10	IMP		Human	PMID:23575687
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP10	IDA		Human	PMID:18851833
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP10	IMP		Human	PMID:24695737
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP10	IDA		Human	PMID:25043379
Molecular Function	GO:0005515	protein binding	PARP10	IPI	UniProtKB:A4D8X6	Human	PMID:22176891
Molecular Function	GO:0005515	protein binding	PARP10	IPI	UniProtKB:Q2EMV9	Human	PMID:23473667
Molecular Function	GO:0005515	protein binding	PARP10	IPI	UniProtKB:Q460N5	Human	PMID:23473667
Molecular Function	GO:0005515	protein binding	PARP10	IPI	UniProtKB:Q9Y530	Human	PMID:23481255
Molecular Function	GO:0005515	protein binding	PARP10	IPI	UniProtKB:P12004	Human	PMID:24695737
Cellular Component	GO:0005737	cytoplasm	PARP10	IDA		Human	PMID:15674325
Cellular Component	GO:0005737	cytoplasm	PARP10	IDA		Human	PMID:22176891
Cellular Component	GO:0005737	cytoplasm	PARP10	IDA		Human	PMID:23473667
Cellular Component	GO:0005829	cytosol	PARP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	PARP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	PARP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PARP10	IDA		Human	PMID:15674325
Cellular Component	GO:0005634	nucleus	PARP10	IDA		Human	PMID:22176891
Cellular Component	GO:0005634	nucleus	PARP10	IDA		Human	PMID:23473667
Biological Process	GO:0006325	chromatin organization	PARP10	IDA		Human	PMID:15674325
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	PARP10	IDA		Human	PMID:15674325
Biological Process	GO:0010629	negative regulation of gene expression	PARP10	IMP		Human	PMID:23575687
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	PARP10	IMP		Human	PMID:23575687
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	PARP10	IMP		Human	PMID:23575687
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP10	IMP		Human	PMID:23575687
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP10	IDA		Human	PMID:25043379
Biological Process	GO:0070212	protein poly-ADP-ribosylation	PARP10	IDA		Human	PMID:15674325
Biological Process	GO:0070212	protein poly-ADP-ribosylation	PARP10	IMP		Human	PMID:23473667
Biological Process	GO:0019985	translesion synthesis	PARP10	IDA		Human	PMID:24695737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern