Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARP16
  • Mouse genes Parp16
  • Rat genes Parp16
  • Zfish genes parp16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Parp16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019900	kinase binding	PARP16	IPI	UniProtKB:O75460	Human	PMID:23103912
Molecular Function	GO:0019900	kinase binding	PARP16	IPI	UniProtKB:Q9NZJ5	Human	PMID:23103912
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP16	IMP		Human	PMID:22701565
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP16	IMP		Human	PMID:23103912
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	PARP16	IDA		Human	PMID:25043379
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	PARP16	IDA		Human	PMID:34314702
Molecular Function	GO:0140804	NAD+- protein-lysine ADP-ribosyltransferase activity	PARP16	IDA		Human	PMID:25043379
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP16	IDA		Human	PMID:25043379
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	PARP16	IDA		Human	PMID:25043379
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	PARP16	IDA		Human	PMID:34314702
Molecular Function	GO:0005515	protein binding	PARP16	IPI	UniProtKB:Q14974	Human	PMID:22701565
Molecular Function	GO:0005515	protein binding	PARP16	IPI	UniProtKB:Q53SE7	Human	PMID:25416956
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	PARP16	IMP		Human	PMID:23103912
Molecular Function	GO:0045182	translation regulator activity	PARP16	IDA		Human	PMID:34314702
Cellular Component	GO:0005783	endoplasmic reticulum	PARP16	IMP		Human	PMID:23103912
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	PARP16	IMP		Human	PMID:22701565
Cellular Component	GO:0016020	membrane	PARP16	HDA		Human	PMID:19946888
Cellular Component	GO:0005635	nuclear envelope	PARP16	IDA		Human	PMID:22701565
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Parp16	IEP		Mouse	PMID:20439489
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	PARP16	IMP		Human	PMID:23103912
Biological Process	GO:0036498	IRE1-mediated unfolded protein response	PARP16	IMP		Human	PMID:23103912
Biological Process	GO:0060548	negative regulation of cell death	PARP16	IMP		Human	PMID:23103912
Biological Process	GO:2000766	negative regulation of cytoplasmic translation	PARP16	IDA		Human	PMID:34314702
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	PARP16	IMP		Human	PMID:23103912
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP16	IMP		Human	PMID:22701565
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP16	IMP		Human	PMID:23103912
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP16	IDA		Human	PMID:25043379
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP16	IDA		Human	PMID:34314702

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern