Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARP3
  • Mouse genes Parp3
  • Rat genes Parp3
  • Zfish genes parp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Parp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140294	NAD DNA ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:29361132
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:21211721
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:21270334
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:20064938
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:25043379
Molecular Function	GO:0140804	NAD+- protein-lysine ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:25043379
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:20064938
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:24598253
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:25043379
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:20064938
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	PARP3	IDA		Human	PMID:25043379
Molecular Function	GO:0005515	protein binding	PARP3	IPI	UniProtKB:P09874	Human	PMID:20064938
Cellular Component	GO:0045171	intercellular bridge	PARP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	PARP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PARP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035861	site of double-strand break	PARP3	IDA		Human	PMID:21270334
Cellular Component	GO:0035861	site of double-strand break	Parp3	IDA		Mouse	PMID:21270334
Biological Process	GO:0030592	DNA ADP-ribosylation	PARP3	IDA		Human	PMID:29361132
Biological Process	GO:0006302	double-strand break repair	PARP3	IMP		Human	PMID:21211721
Biological Process	GO:0006302	double-strand break repair	PARP3	IDA		Human	PMID:21270334
Biological Process	GO:0006302	double-strand break repair	Parp3	IGI	MGI:MGI:1340806	Mouse	PMID:21270334
Biological Process	GO:0071696	ectodermal placode development	parp3	IMP	ZFIN:ZDB-MRPHLNO-110324-2	Zfish	PMID:21264220
Biological Process	GO:0071696	ectodermal placode development	parp3	IMP	ZFIN:ZDB-MRPHLNO-110324-3	Zfish	PMID:21264220
Biological Process	GO:0045829	negative regulation of isotype switching	Parp3	IMP		Mouse	MGI:MGI:6214451|PMID:26000965
Biological Process	GO:1905662	negative regulation of telomerase RNA reverse transcriptase activity	PARP3	IMP		Human	PMID:24528514
Biological Process	GO:0051106	positive regulation of DNA ligation	PARP3	IGI	UniProtKB:Q8IW19	Human	PMID:21211721
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	PARP3	IDA		Human	PMID:24598253
Biological Process	GO:0070213	protein auto-ADP-ribosylation	PARP3	IDA		Human	PMID:25043379
Biological Process	GO:1990166	protein localization to site of double-strand break	PARP3	IMP		Human	PMID:21211721
Biological Process	GO:0060236	regulation of mitotic spindle organization	PARP3	IMP		Human	PMID:21270334
Biological Process	GO:0090299	regulation of neural crest formation	parp3	IMP	ZFIN:ZDB-MRPHLNO-110324-2	Zfish	PMID:21264220
Biological Process	GO:0090299	regulation of neural crest formation	parp3	IMP	ZFIN:ZDB-MRPHLNO-110324-3	Zfish	PMID:21264220
Biological Process	GO:0000723	telomere maintenance	PARP3	IMP		Human	PMID:21270334

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern