Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARP4
  • Mouse genes Parp4
  • Rat genes
  • Zfish genes parp4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Parp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	PARP4	IDA		Human	PMID:15169895
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP4	IDA		Human	PMID:10477748
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP4	IDA		Human	PMID:25043379
Molecular Function	GO:0005515	protein binding	PARP4	IPI	UniProtKB:Q99973	Human	PMID:15169895
Molecular Function	GO:0005515	protein binding	PARP4	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Cellular Component	GO:0005737	cytoplasm	PARP4	IDA		Human	PMID:10477748
Cellular Component	GO:0005829	cytosol	PARP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	PARP4	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	PARP4	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	PARP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005876	spindle microtubule	PARP4	IDA		Human	PMID:10477748
Biological Process	GO:0008219	cell death	PARP4	IMP		Human	PMID:12140175
Biological Process	GO:0006954	inflammatory response	PARP4	IMP		Human	PMID:12123754
Biological Process	GO:0036211	protein modification process	PARP4	IDA		Human	PMID:10477748
Biological Process	GO:0051972	regulation of telomerase activity	PARP4	IDA		Human	PMID:15169895

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern