Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARVA
  • Mouse genes Parva
  • Rat genes Parva
  • Zfish genes parvaa,parvab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Parva

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Parva	IDA		Mouse	PMID:11171322
Molecular Function	GO:0003779	actin binding	Parva	IDA		Mouse	PMID:11134073
Molecular Function	GO:0045296	cadherin binding	PARVA	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:O55222	Human	PMID:11331308
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:11331308
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:12432066
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:P49024	Human	PMID:15817463
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:15817463
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q63572	Human	PMID:15817463
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:17553790
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q96EN8	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:23877428
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q96EN8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q96EN8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:30254023
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:Q13418	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PARVA	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Parva	IPI	UniProtKB:O55222	Mouse	MGI:MGI:4367148|PMID:19829382
Molecular Function	GO:0005515	protein binding	Parva	IPI	UniProtKB:O55222	Mouse	MGI:MGI:4368016|PMID:19798050
Molecular Function	GO:0005515	protein binding	Parva	IPI	UniProtKB:O55222	Mouse	MGI:MGI:6368070|PMID:11331308
Molecular Function	GO:0005515	protein binding	Parva	IPI	UniProtKB:O55222	Mouse	MGI:MGI:5499269|PMID:23612611
Molecular Function	GO:0005515	protein binding	Parva	IPI	PR:Q99JW4	Mouse	PMID:12432066
Molecular Function	GO:0005515	protein binding	Parva	IPI	PR:O55222	Mouse	PMID:12432066
Molecular Function	GO:0004860	protein kinase inhibitor activity	PARVA	IMP		Human	PMID:15817463
Molecular Function	GO:0044877	protein-containing complex binding	Parva	IDA		Rat	PMID:17167118|RGD:2302524
Molecular Function	GO:0044877	protein-containing complex binding	Parva	IPI	RGD:620063|RGD:1560732	Rat	PMID:17934340|RGD:2301743
Cellular Component	GO:0015629	actin cytoskeleton	PARVA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Parva	IDA		Mouse	PMID:11171322
Cellular Component	GO:0005829	cytosol	PARVA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	PARVA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	PARVA	IDA		Human	PMID:11331308
Cellular Component	GO:0005925	focal adhesion	PARVA	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	PARVA	IDA		Human	PMID:29162887
Cellular Component	GO:0005925	focal adhesion	Parva	IDA		Mouse	PMID:11171322
Cellular Component	GO:0005925	focal adhesion	Parva	IDA		Mouse	PMID:23658024
Cellular Component	GO:0005925	focal adhesion	Parva	IDA		Mouse	PMID:11134073
Cellular Component	GO:0030027	lamellipodium	Parva	IDA		Mouse	PMID:11171322
Cellular Component	GO:0005634	nucleus	Parva	IDA		Mouse	PMID:11171322
Cellular Component	GO:0032991	protein-containing complex	Parva	IDA		Rat	PMID:17167118|RGD:2302524
Cellular Component	GO:0032991	protein-containing complex	Parva	IDA		Rat	PMID:17934340|RGD:2301743
Biological Process	GO:0030036	actin cytoskeleton organization	Parva	IDA		Rat	PMID:11931650|RGD:633557
Biological Process	GO:0070252	actin-mediated cell contraction	Parva	IMP		Mouse	MGI:MGI:4368016|PMID:19798050
Biological Process	GO:0007155	cell adhesion	Parva	IDA		Mouse	PMID:11134073
Biological Process	GO:0060271	cilium assembly	PARVA	IMP		Human	PMID:20393563
Biological Process	GO:0007163	establishment or maintenance of cell polarity	Parva	IMP		Mouse	MGI:MGI:4368016|PMID:19798050
Biological Process	GO:0034113	heterotypic cell-cell adhesion	Parva	IMP		Mouse	MGI:MGI:4368016|PMID:19798050
Biological Process	GO:0003148	outflow tract septum morphogenesis	Parva	IMP		Mouse	MGI:MGI:4368016|PMID:19798050
Biological Process	GO:0071670	smooth muscle cell chemotaxis	Parva	IMP		Mouse	MGI:MGI:4368016|PMID:19798050
Biological Process	GO:0002040	sprouting angiogenesis	Parva	IMP		Mouse	MGI:MGI:4368016|PMID:19798050
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	PARVA	IMP		Human	PMID:11331308
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Parva	IMP		Mouse	MGI:MGI:4368016|PMID:19798050

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern