Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pawr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PAWR
- Mouse genes Pawr
- Rat genes Pawr
- Zfish genes pawr
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pawr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Pawr	IDA		Rat	PMID:16229834\|RGD:8554822
Molecular Function	GO:0019899	enzyme binding	PAWR	IDA		Human	PMID:15671026
Molecular Function	GO:0043522	leucine zipper domain binding	PAWR	IPI	UniProtKB:Q9NY61	Human	PMID:14627703
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:P37198	Human	PMID:11755531
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:O88838	Human	PMID:16369487
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:Q8R5B6	Human	PMID:16369487
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:Q9D5L7	Human	PMID:16369487
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:Q01094	Human	PMID:18660514
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:P11021	Human	PMID:19632185
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:O88838	Human	PMID:20561531
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:Q8R5B6	Human	PMID:20561531
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:Q96BD6	Human	PMID:20561531
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:Q9D5L7	Human	PMID:20561531
Molecular Function	GO:0005515	protein binding	PAWR	IPI	UniProtKB:P08670	Human	PMID:25218743
Molecular Function	GO:0005515	protein binding	Pawr	IPI	UniProtKB:O54784	Mouse	MGI:MGI:3687891\|PMID:12917339
Molecular Function	GO:0005515	protein binding	Pawr	IPI	PR:Q9JKX4	Mouse	PMID:14627703
Molecular Function	GO:0005515	protein binding	Pawr	IPI	RGD:621766	Rat	PMID:10602480\|RGD:8554171
Molecular Function	GO:0005515	protein binding	Pawr	IPI	UniProtKB:O88764	Rat	PMID:10602480\|RGD:8554171
Molecular Function	GO:0005515	protein binding	Pawr	IPI	UniProtKB:Q9JMG6	Rat	PMID:16229834\|RGD:8554822
Molecular Function	GO:0005515	protein binding	Pawr	IPI	UniProtKB:P11021	Rat	PMID:19632185\|RGD:8553900
Molecular Function	GO:0005515	protein binding	Pawr	IPI	RGD:620013	Rat	PMID:23219599\|RGD:9835413
Molecular Function	GO:0005515	protein binding	Pawr	IPI	RGD:733323	Rat	PMID:24457960\|RGD:9835368
Molecular Function	GO:0005080	protein kinase C binding	Pawr	IPI	RGD:3399	Rat	PMID:17219052\|RGD:9835345
Molecular Function	GO:0008157	protein phosphatase 1 binding	Pawr	IPI	RGD:3376\|RGD:620013	Rat	PMID:20130087\|RGD:9835415
Cellular Component	GO:0015629	actin cytoskeleton	PAWR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005884	actin filament	Pawr	IDA		Rat	PMID:15817164\|RGD:9835355
Cellular Component	GO:0005884	actin filament	Pawr	IDA		Rat	PMID:16229834\|RGD:8554822
Cellular Component	GO:0030424	axon	Pawr	IDA		Rat	PMID:19859967\|RGD:9835383
Cellular Component	GO:0000785	chromatin	Pawr	IDA		Mouse	MGI:MGI:5648604\|PMID:25472717
Cellular Component	GO:0005737	cytoplasm	PAWR	IDA		Human	PMID:14627703
Cellular Component	GO:0005737	cytoplasm	Pawr	IDA		Mouse	PMID:14627703
Cellular Component	GO:0005737	cytoplasm	Pawr	IDA		Rat	PMID:9269897\|RGD:9835360
Cellular Component	GO:0005829	cytosol	PAWR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043005	neuron projection	Pawr	IDA		Rat	PMID:10349840\|RGD:9835366
Cellular Component	GO:0043025	neuronal cell body	Pawr	IDA		Rat	PMID:10349840\|RGD:9835366
Cellular Component	GO:0005634	nucleus	PAWR	IDA		Human	PMID:14627703
Cellular Component	GO:0005634	nucleus	Pawr	IDA		Mouse	PMID:14627703
Cellular Component	GO:0005634	nucleus	Pawr	IDA		Mouse	PMID:12917339
Cellular Component	GO:0005886	plasma membrane	PAWR	IDA		Human	GO_REF:0000052
Biological Process	GO:0051017	actin filament bundle assembly	Pawr	IDA		Rat	PMID:16229834\|RGD:8554822
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	Pawr	IMP		Rat	PMID:10349840\|RGD:9835366
Biological Process	GO:0006915	apoptotic process	Pawr	IDA		Rat	PMID:16229834\|RGD:8554822
Biological Process	GO:0006915	apoptotic process	Pawr	IEP		Rat	PMID:17219052\|RGD:9835345
Biological Process	GO:0097190	apoptotic signaling pathway	Pawr	IGI	MGI:MGI:1197015	Mouse	PMID:12917339
Biological Process	GO:0097190	apoptotic signaling pathway	Pawr	IGI	MGI:MGI:1203520	Mouse	PMID:12917339
Biological Process	GO:0098703	calcium ion import across plasma membrane	Pawr	IDA		Rat	PMID:18294734\|RGD:9835370
Biological Process	GO:0071392	cellular response to estradiol stimulus	Pawr	IEP		Rat	PMID:10428045\|RGD:9835341
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Pawr	IEP		Rat	PMID:17219052\|RGD:9835345
Biological Process	GO:0071347	cellular response to interleukin-1	Pawr	IEP		Rat	PMID:23775412\|RGD:9835367
Biological Process	GO:0071306	cellular response to vitamin E	Pawr	IEP		Rat	PMID:10428045\|RGD:9835341
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	Pawr	IDA		Rat	PMID:21238854\|RGD:9835398
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	Pawr	IDA		Rat	PMID:17179954\|RGD:9835416
Biological Process	GO:0032623	interleukin-2 production	Pawr	IMP	MGI:MGI:2678021	Mouse	PMID:12970181
Biological Process	GO:0030889	negative regulation of B cell proliferation	Pawr	IMP	MGI:MGI:2678021	Mouse	PMID:12970181
Biological Process	GO:0090281	negative regulation of calcium ion import	Pawr	IDA		Rat	PMID:17179954\|RGD:9835416
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	Pawr	IMP		Mouse	MGI:MGI:5648604\|PMID:25472717
Biological Process	GO:0010629	negative regulation of gene expression	Pawr	IMP		Mouse	MGI:MGI:5648604\|PMID:25472717
Biological Process	GO:0042130	negative regulation of T cell proliferation	Pawr	IMP	MGI:MGI:2678021	Mouse	PMID:12970181
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	Pawr	IMP	MGI:MGI:2678021	Mouse	PMID:12970181
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pawr	IMP		Mouse	MGI:MGI:5648604\|PMID:25472717
Biological Process	GO:0045760	positive regulation of action potential	Pawr	IDA		Rat	PMID:21238854\|RGD:9835398
Biological Process	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	Pawr	IDA		Mouse	PMID:14627703
Biological Process	GO:0043065	positive regulation of apoptotic process	Pawr	IMP		Rat	PMID:10428045\|RGD:9835341
Biological Process	GO:2000774	positive regulation of cellular senescence	Pawr	IMP		Mouse	MGI:MGI:5648604\|PMID:25472717
Biological Process	GO:0010628	positive regulation of gene expression	Pawr	IMP		Mouse	MGI:MGI:5648604\|PMID:25472717
Biological Process	GO:0060450	positive regulation of hindgut contraction	Pawr	IDA		Rat	PMID:14724155\|RGD:9835340
Biological Process	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death	Pawr	IMP		Mouse	MGI:MGI:5648604\|PMID:25472717
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	Pawr	IDA		Rat	PMID:12133973\|RGD:9835372
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Pawr	IMP		Rat	PMID:11323519\|RGD:9835381
Biological Process	GO:1904457	positive regulation of neuronal action potential	Pawr	IMP		Rat	PMID:19889854\|RGD:9835339
Biological Process	GO:2000391	positive regulation of neutrophil extravasation	Pawr	IDA		Rat	PMID:12133973\|RGD:9835372
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	Pawr	IMP		Rat	PMID:23219599\|RGD:9835413
Biological Process	GO:1901082	positive regulation of relaxation of smooth muscle	Pawr	IDA		Rat	PMID:11015310\|RGD:9835373
Biological Process	GO:0043114	regulation of vascular permeability	pawr	IGI	ZFIN:ZDB-MRPHLNO-130110-5,ZFIN:ZDB-MRPHLNO-130110-6	Zfish	PMID:21282189
Biological Process	GO:0043114	regulation of vascular permeability	pawr	IGI	ZFIN:ZDB-MRPHLNO-061111-2,ZFIN:ZDB-MRPHLNO-061111-3,ZFIN:ZDB-MRPHLNO-130110-6	Zfish	PMID:21282189
Biological Process	GO:0032355	response to estradiol	Pawr	IEP		Rat	PMID:15964511\|RGD:9835363
Biological Process	GO:0010040	response to iron(II) ion	Pawr	IEP		Rat	PMID:10349840\|RGD:9835366
Biological Process	GO:0032496	response to lipopolysaccharide	Pawr	IEP		Rat	PMID:17136598\|RGD:9835397
Biological Process	GO:0009611	response to wounding	Pawr	IEP		Rat	PMID:12836167\|RGD:1299297

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.