Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAX1
  • Mouse genes Pax1
  • Rat genes Pax1
  • Zfish genes pax1a,pax1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pax1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pax1	IDA		Mouse	MGI:MGI:2448169|PMID:12490554
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pax1	IMP		Mouse	MGI:MGI:2448169|PMID:12490554
Molecular Function	GO:0005515	protein binding	pax1b	IPI	GenPept:NP_002006	Zfish	PMID:25197636
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pax1	IMP		Mouse	MGI:MGI:2448169|PMID:12490554
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	PAX1	IDA		Human	PMID:28473536
Biological Process	GO:0060349	bone morphogenesis	Pax1	IMP	MGI:MGI:1856225	Mouse	PMID:7607069
Biological Process	GO:0060349	bone morphogenesis	Pax1	IMP	MGI:MGI:1856223	Mouse	PMID:7607069
Biological Process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	Pax1	IMP	MGI:MGI:3603176	Mouse	PMID:16093716
Biological Process	GO:0043374	CD8-positive, alpha-beta T cell differentiation	Pax1	IMP	MGI:MGI:3603176	Mouse	PMID:16093716
Biological Process	GO:0008283	cell population proliferation	Pax1	IMP	MGI:MGI:1857560	Mouse	PMID:10364424
Biological Process	GO:0048706	embryonic skeletal system development	pax1b	IMP	ZFIN:ZDB-MRPHLNO-140513-6	Zfish	PMID:24463529
Biological Process	GO:0060017	parathyroid gland development	Pax1	IGI	MGI:MGI:96175	Mouse	PMID:11476574
Biological Process	GO:0007389	pattern specification process	Pax1	IMP	MGI:MGI:1856222	Mouse	PMID:11900462
Biological Process	GO:0033339	pectoral fin development	pax1b	IMP	ZFIN:ZDB-MRPHLNO-140513-6,ZFIN:ZDB-MRPHLNO-141211-1	Zfish	PMID:25197636
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax1	IDA		Mouse	MGI:MGI:2448169|PMID:12490554
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax1	IGI	MGI:MGI:108015	Mouse	PMID:15024065
Biological Process	GO:0061056	sclerotome development	Pax1	IEP		Mouse	MGI:MGI:72077|PMID:7743923
Biological Process	GO:0001501	skeletal system development	Pax1	IMP	MGI:MGI:1857560	Mouse	PMID:10364424
Biological Process	GO:0001501	skeletal system development	Pax1	IGI	MGI:MGI:1347481	Mouse	PMID:10364424
Biological Process	GO:0001501	skeletal system development	Pax1	IMP	MGI:MGI:1856222	Mouse	PMID:11900462
Biological Process	GO:0001756	somitogenesis	Pax1	IMP	MGI:MGI:3603176	Mouse	PMID:16093716
Biological Process	GO:0048538	thymus development	Pax1	IGI	MGI:MGI:96175	Mouse	PMID:11476574

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern