Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAX3
  • Mouse genes Pax3
  • Rat genes Pax3
  • Zfish genes pax3a,pax3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pax3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pax3	IDA		Mouse	PMID:15729346
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pax3	IGI	MGI:MGI:96770	Mouse	PMID:15729346
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pax3	IDA		Mouse	PMID:15729346
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pax3	IGI	MGI:MGI:88276	Mouse	PMID:15729346
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pax3	IGI	MGI:MGI:104633	Mouse	PMID:15729346
Molecular Function	GO:0071837	HMG box domain binding	Pax3	IPI	UniProtKB:O55170	Rat	PMID:16582099|RGD:6892704
Molecular Function	GO:0071837	HMG box domain binding	Pax3	IPI	UniProtKB:Q04886	Rat	PMID:16582099|RGD:6892704
Molecular Function	GO:0071837	HMG box domain binding	Pax3	IPI	UniProtKB:Q05066	Rat	PMID:16582099|RGD:6892704
Molecular Function	GO:0005515	protein binding	PAX3	IPI	UniProtKB:P20265	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	PAX3	IPI	UniProtKB:P56693	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	Pax3	IPI	UniProtKB:P0CG47|UniProtKB:P54727|UniProtKB:P55036	Mouse	MGI:MGI:3763316|PMID:17662948
Molecular Function	GO:0005515	protein binding	Pax3	IPI	UniProtKB:P13405|UniProtKB:P28749|UniProtKB:Q08999	Mouse	MGI:MGI:1195383|PMID:9464541
Molecular Function	GO:0005515	protein binding	Pax3	IPI	PR:Q62441	Mouse	PMID:15729346
Molecular Function	GO:0005515	protein binding	Pax3	IPI	PR:Q9EPK5	Mouse	PMID:16300735
Molecular Function	GO:0005515	protein binding	Pax3	IPI	PR:P58501	Mouse	PMID:22862948
Molecular Function	GO:0043565	sequence-specific DNA binding	PAX3	IDA		Human	PMID:11863357
Molecular Function	GO:0043565	sequence-specific DNA binding	Pax3	IDA		Mouse	PMID:11863357
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	PAX3	IDA		Human	PMID:28473536
Molecular Function	GO:0001221	transcription coregulator binding	Pax3	IPI	UniProtKB:P54198	Mouse	MGI:MGI:6436964|PMID:9731536
Cellular Component	GO:0005654	nucleoplasm	PAX3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Pax3	IDA		Mouse	PMID:21177767
Cellular Component	GO:0005634	nucleus	pax3a	IDA		Zfish	PMID:18417109
Biological Process	GO:0014707	branchiomeric skeletal muscle development	pax3b	IMP	ZFIN:ZDB-MRPHLNO-130821-1	Zfish	PMID:23760954
Biological Process	GO:0016477	cell migration	Pax3	IMP	MGI:MGI:1856173	Mouse	PMID:17974128
Biological Process	GO:0008283	cell population proliferation	Pax3	IMP	MGI:MGI:1856293	Mouse	PMID:10946068
Biological Process	GO:0048066	developmental pigmentation	Pax3	IMP	MGI:MGI:1856173	Mouse	PMID:15322542
Biological Process	GO:0048066	developmental pigmentation	pax3a	IMP	ZFIN:ZDB-MRPHLNO-080911-3	Zfish	PMID:18417109
Biological Process	GO:0048066	developmental pigmentation	pax3a	IMP	ZFIN:ZDB-MRPHLNO-080911-2	Zfish	PMID:18417109
Biological Process	GO:0048484	enteric nervous system development	pax3a	IMP	ZFIN:ZDB-MRPHLNO-080911-2	Zfish	PMID:18417109
Biological Process	GO:0007507	heart development	Pax3	IMP	MGI:MGI:1856173	Mouse	PMID:10231856
Biological Process	GO:0060594	mammary gland specification	Pax3	IMP	MGI:MGI:2687297	Mouse	PMID:16720875
Biological Process	GO:0007517	muscle organ development	Pax3	IMP	MGI:MGI:3047632	Mouse	PMID:15132998
Biological Process	GO:0007517	muscle organ development	Pax3	IMP	MGI:MGI:3047631	Mouse	PMID:15132998
Biological Process	GO:0007517	muscle organ development	Pax3	IMP	MGI:MGI:2687297	Mouse	PMID:15132998
Biological Process	GO:0007517	muscle organ development	Pax3	IMP	MGI:MGI:1856173	Mouse	PMID:15132998
Biological Process	GO:0051451	myoblast migration	Pax3	IMP	MGI:MGI:3047631	Mouse	PMID:15132998
Biological Process	GO:0051451	myoblast migration	Pax3	IMP	MGI:MGI:1856173	Mouse	PMID:15132998
Biological Process	GO:0051451	myoblast migration	Pax3	IMP	MGI:MGI:2687297	Mouse	PMID:15132998
Biological Process	GO:0051451	myoblast migration	Pax3	IMP	MGI:MGI:3047632	Mouse	PMID:15132998
Biological Process	GO:0051450	myoblast proliferation	Pax3	IMP	MGI:MGI:2687297	Mouse	PMID:15132998
Biological Process	GO:0051450	myoblast proliferation	Pax3	IMP	MGI:MGI:3047632	Mouse	PMID:15132998
Biological Process	GO:0051450	myoblast proliferation	Pax3	IMP	MGI:MGI:1856173	Mouse	PMID:15132998
Biological Process	GO:0051450	myoblast proliferation	Pax3	IMP	MGI:MGI:3047631	Mouse	PMID:15132998
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pax3	IGI	MGI:MGI:98358	Mouse	PMID:15729346
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pax3	IGI	MGI:MGI:104554	Mouse	PMID:15729346
Biological Process	GO:0001755	neural crest cell migration	Pax3	IMP	MGI:MGI:3043030	Mouse	PMID:15384171
Biological Process	GO:0001755	neural crest cell migration	pax3a	IMP	ZFIN:ZDB-MRPHLNO-080911-2	Zfish	PMID:18417109
Biological Process	GO:0001843	neural tube closure	Pax3	IMP	MGI:MGI:3043030	Mouse	PMID:15384171
Biological Process	GO:0021915	neural tube development	Pax3	IGI	MGI:MGI:97306	Mouse	PMID:10419687
Biological Process	GO:0048663	neuron fate commitment	Pax3	IGI	MGI:MGI:97491	Mouse	PMID:9858722
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	PAX3	IDA		Human	PMID:11863357
Biological Process	GO:2000648	positive regulation of stem cell proliferation	Pax3	IMP	MGI:MGI:1856293	Mouse	PMID:10946068
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PAX3	IDA		Human	PMID:11863357
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax3	IDA		Mouse	PMID:16300735
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax3	IDA		Mouse	PMID:15729346
Biological Process	GO:0014807	regulation of somitogenesis	Pax3	IGI	MGI:MGI:1330307	Mouse	PMID:17974128
Biological Process	GO:0014807	regulation of somitogenesis	Pax3	IMP	MGI:MGI:1856173	Mouse	PMID:17974128
Biological Process	GO:0060538	skeletal muscle organ development	Pax3	IMP	MGI:MGI:1856174	Mouse	PMID:24443808
Biological Process	GO:0021527	spinal cord association neuron differentiation	Pax3	IGI	MGI:MGI:97491	Mouse	PMID:9858722
Biological Process	GO:0072089	stem cell proliferation	Pax3	IMP	MGI:MGI:1856293	Mouse	PMID:10946068
Biological Process	GO:0050936	xanthophore differentiation	pax3a	IMP	ZFIN:ZDB-MRPHLNO-080911-2	Zfish	PMID:18417109
Biological Process	GO:0050936	xanthophore differentiation	pax3a	IMP	ZFIN:ZDB-MRPHLNO-080911-3	Zfish	PMID:18417109

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern