Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAX5
  • Mouse genes Pax5
  • Rat genes Pax5
  • Zfish genes pax5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pax5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pax5	IDA		Mouse	PMID:14594818
Molecular Function	GO:0003677	DNA binding	Pax5	IMP	MGI:MGI:1926938	Mouse	PMID:16618805
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pax5	IDA		Mouse	MGI:MGI:5572893|PMID:12244173
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pax5	IDA		Mouse	PMID:14594818
Molecular Function	GO:0060090	molecular adaptor activity	PAX5	EXP		Human	PMID:12221090
Molecular Function	GO:0060090	molecular adaptor activity	PAX5	EXP		Human	PMID:27067111
Molecular Function	GO:0003676	nucleic acid binding	PAX5	EXP		Human	PMID:12221090
Molecular Function	GO:0003676	nucleic acid binding	PAX5	EXP		Human	PMID:27067111
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q03164:PRO_0000390949	Human	PMID:24735925
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:O15347	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:O75934	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:O94888	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P23142-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P24863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P43351	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P45984	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P61024	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:P68400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q00526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q13952-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q14CS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q17RB8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q2WGJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q5SW96	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q6ISB3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q6NT76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q6P4E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q86UE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q8TB03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q8WYK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q969S2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q96IV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q96PV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q96Q77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q99469	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q9P2W3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q9UBE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q9UDX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q9UJ78-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PAX5	IPI	UniProtKB:Q9UJX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pax5	IPI	UniProtKB:Q9UER7	Mouse	MGI:MGI:3688031|PMID:11799127
Molecular Function	GO:0005515	protein binding	Pax5	IPI	UniProtKB:Q6NZQ4	Mouse	MGI:MGI:5013490|PMID:21552207
Molecular Function	GO:0005515	protein binding	Pax5	IPI	UniProtKB:O35613|UniProtKB:P45481	Mouse	MGI:MGI:3688031|PMID:11799127
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pax5	IDA		Mouse	MGI:MGI:5572893|PMID:12244173
Cellular Component	GO:0005654	nucleoplasm	PAX5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Pax5	IDA		Mouse	PMID:14594818
Biological Process	GO:0030534	adult behavior	Pax5	IMP	MGI:MGI:2386577	Mouse	PMID:23349049
Biological Process	GO:0021987	cerebral cortex development	Pax5	IMP	MGI:MGI:2386577	Mouse	PMID:23349049
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	Pax5	IMP	MGI:MGI:2386577	Mouse	PMID:23349049
Biological Process	GO:0021670	lateral ventricle development	Pax5	IMP	MGI:MGI:2386577	Mouse	PMID:23349049
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pax5	IMP	MGI:MGI:1926938	Mouse	PMID:16618805
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pax5	IDA		Mouse	PMID:15258579
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax5	IDA		Mouse	MGI:MGI:5572893|PMID:12244173
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax5	IGI	MGI:MGI:1338823	Mouse	PMID:15094381
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax5	IGI	MGI:MGI:96770	Mouse	PMID:15094381
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pax5	IGI	MGI:MGI:97249	Mouse	PMID:15094381
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pax5	IDA		Mouse	PMID:14594818
Biological Process	GO:0035914	skeletal muscle cell differentiation	Pax5	IMP		Mouse	PMID:22147266
Biological Process	GO:0060118	vestibular receptor cell development	pax5	IMP	ZFIN:ZDB-MRPHLNO-070102-2,ZFIN:ZDB-MRPHLNO-070102-3,ZFIN:ZDB-MRPHLNO-070102-4,ZFIN:ZDB-MRPHLNO-070102-5,ZFIN:ZDB-MRPHLNO-070102-6	Zfish	PMID:17013878
Biological Process	GO:0060005	vestibular reflex	pax5	IMP	ZFIN:ZDB-MRPHLNO-070102-2,ZFIN:ZDB-MRPHLNO-070102-3,ZFIN:ZDB-MRPHLNO-070102-4,ZFIN:ZDB-MRPHLNO-070102-5,ZFIN:ZDB-MRPHLNO-070102-6	Zfish	PMID:17013878

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern