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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pax6

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pax6
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingPax6IDAMousePMID:24488179
Molecular FunctionGO:0003682chromatin bindingPax6IDAMousePMID:19146846
Molecular FunctionGO:0003682chromatin bindingPax6IDAMousePMID:23637604
Molecular FunctionGO:0031490chromatin DNA bindingPax6IDAMousePMID:30186101
Molecular FunctionGO:0070410co-SMAD bindingPax6IDAMouseMGI:MGI:5009398|PMID:17251190
Molecular FunctionGO:0003677DNA bindingPax6IDAMousePMID:12756174
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificPax6IDAMouseMGI:MGI:2662558|PMID:12756174
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificPax6IDAMousePMID:22031545
Molecular FunctionGO:0003700DNA-binding transcription factor activityPax6IDAMousePMID:18287938
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificPAX6IDAHumanPMID:20592023
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificPax6IDAMouseMGI:MGI:4943812|PMID:20592023
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificPax6IDAMouseMGI:MGI:5306308|PMID:16407227
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificPax6IDARatPMID:20592023|RGD:8552352
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificpax6bIDAZfishPMID:9831649
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificpax6bIDAZfishPMID:18282108
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificpax6aIDAZfishPMID:9831649
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificpax6aIDAZfishPMID:18282108
Molecular FunctionGO:0001227DNA-binding transcription repressor activity, RNA polymerase II-specificPax6IDAMousePMID:23622063
Molecular FunctionGO:0003690double-stranded DNA bindingPax6IDARatPMID:12370174|RGD:632189
Molecular FunctionGO:0035035histone acetyltransferase bindingPax6IDAMouseMGI:MGI:5306308|PMID:16407227
Molecular FunctionGO:0071837HMG box domain bindingPax6IPIUniProtKB:O55170MouseMGI:MGI:5284787|PMID:16582099
Molecular FunctionGO:0003680minor groove of adenine-thymine-rich DNA bindingPax6IDARatPMID:12370174|RGD:632189
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P63168HumanPMID:16098226
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9NSC5HumanPMID:16098226
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:A0A384ME25HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:A0AV02HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O14893HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O14964HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O15347HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O43699-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O75603HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O75865-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O94888HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O95376HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O95872HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:O96006HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P07910HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P31273HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P31274HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P49366HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P49639HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P54619HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P55081HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P61024HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P61086HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P62508-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:P68400HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q00526HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q01105-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q05519-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q08493-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q13111HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q13526HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q13952-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q14CS0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q15642-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q15691HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q15973HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q16204HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q17RB8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q2TAL8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q3SXR9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q53TS8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q5JVL4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q5MJ68HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q5TBC7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q63ZY3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q6ISB3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q6NT76HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q6P4E2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q6PF18HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q86UE8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q86VK4-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8IVT2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8IW40HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8N6Y0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8N8Y2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8N9N5-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8N9N8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8NEY4-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8NHY3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8NI38HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8TB03HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8TD10HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8WUA2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q8WYK0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q969M7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q96EL3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q96FV9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q96IV0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q96JC9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q96MP8-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q96Q77HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q96S90HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q99469HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9BS40HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9BT43HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9BUI4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9BW66HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9BXS5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9BYQ0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9BYQ3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9C0E8-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9NRD5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9NSC5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9NUJ3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9NX04HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9NZD8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9UBB6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9UBE0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9UDX3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9UFW8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9UI47-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9UIG4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9UKI8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9Y247HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9Y258HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPAX6IPIUniProtKB:Q9Y3C0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPax6IPIUniProtKB:Q9WVB3MouseMGI:MGI:6478056|PMID:23990468
Molecular FunctionGO:0005515protein bindingPax6IPIUniProtKB:O35845MouseMGI:MGI:3624889|PMID:16675956
Molecular FunctionGO:0005515protein bindingPax6IPIUniProtKB:P63166MouseMGI:MGI:4867351|PMID:21084637
Molecular FunctionGO:0005515protein bindingPax6IPIPR:Q99PQ2MousePMID:16098226
Molecular FunctionGO:0005515protein bindingPax6IPIPR:P48432MousePMID:23447615
Molecular FunctionGO:0005515protein bindingPax6IPIPR:P63168MousePMID:16098226
Molecular FunctionGO:0005515protein bindingPax6IPIPR:Q99JP6MousePMID:16098226
Molecular FunctionGO:0019901protein kinase bindingPax6IPIUniProtKB:Q9QZR5MouseMGI:MGI:5306308|PMID:16407227
Molecular FunctionGO:0070412R-SMAD bindingPAX6IPIUniProtKB:P84022HumanPMID:17251190
Molecular FunctionGO:0070412R-SMAD bindingPax6IDAMouseMGI:MGI:5009398|PMID:17251190
Molecular FunctionGO:0003723RNA bindingPax6IDAMousePMID:24488179
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingPAX6IDAHumanPMID:20592023
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingPax6IDAMouseMGI:MGI:2662558|PMID:12756174
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingPax6IDAMouseMGI:MGI:4943812|PMID:20592023
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingPax6IDARatPMID:20592023|RGD:8552352
Molecular FunctionGO:0000979RNA polymerase II core promoter sequence-specific DNA bindingPax6IDAMouseMGI:MGI:5306308|PMID:16407227
Molecular FunctionGO:0043565sequence-specific DNA bindingPax6IDAMousePMID:23622063
Molecular FunctionGO:0043565sequence-specific DNA bindingPax6IDARatPMID:12370174|RGD:632189
Molecular FunctionGO:0043565sequence-specific DNA bindingpax6aIDAZfishPMID:8900176
Molecular FunctionGO:1990837sequence-specific double-stranded DNA bindingPAX6IDAHumanPMID:28473536
Molecular FunctionGO:0000976transcription cis-regulatory region bindingPax6IDAMouseMGI:MGI:6478056|PMID:23990468
Molecular FunctionGO:0000976transcription cis-regulatory region bindingPax6IDAMousePMID:19521500
Molecular FunctionGO:0001221transcription coregulator bindingPax6IPIUniProtKB:Q9QZR5MouseMGI:MGI:5306308|PMID:16407227
Molecular FunctionGO:0031625ubiquitin protein ligase bindingPax6IPIUniProtKB:Q99PQ2MouseMGI:MGI:3801352|PMID:18628401
Cellular ComponentGO:0000785chromatinPAX6IDAHumanPMID:20592023
Cellular ComponentGO:0000785chromatinPax6IDAMouseMGI:MGI:4943812|PMID:20592023
Cellular ComponentGO:0000785chromatinPax6IDARatPMID:20592023|RGD:8552352
Cellular ComponentGO:0005737cytoplasmPAX6IDAHumanPMID:17291498
Cellular ComponentGO:0005829cytosolPAX6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005622intracellular anatomical structurePax6IDAMousePMID:15793245
Cellular ComponentGO:0005654nucleoplasmPAX6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusPAX6IDAHumanPMID:17291498
Cellular ComponentGO:0005634nucleusPax6IDAMouseMGI:MGI:6478056|PMID:23990468
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:11209945
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:12050133
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:24466353
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:16464444
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:9230312
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:23434913
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:22764048
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:14625556
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:19409883
Cellular ComponentGO:0005634nucleusPax6IDAMousePMID:25100583
Cellular ComponentGO:0005634nucleusPax6IDARatPMID:12370174|RGD:632189
Cellular ComponentGO:0005634nucleuspax6aIDAZfishPMID:7946344
Biological ProcessGO:0009952anterior/posterior pattern specificationPax6IGIMGI:MGI:95388MousePMID:15917450
Biological ProcessGO:0009952anterior/posterior pattern specificationPax6IMPMGI:MGI:1856155MousePMID:12196586
Biological ProcessGO:0009952anterior/posterior pattern specificationpax6bIMPZFIN:ZDB-MRPHLNO-041116-2ZfishPMID:17010333
Biological ProcessGO:0009952anterior/posterior pattern specificationpax6aIMPZFIN:ZDB-MRPHLNO-041116-1ZfishPMID:17010333
Biological ProcessGO:0048708astrocyte differentiationPax6IMPMousePMID:30186101
Biological ProcessGO:0048708astrocyte differentiationPax6IMPMGI:MGI:1856155MousePMID:19258013
Biological ProcessGO:0048708astrocyte differentiationPax6IMPRatPMID:22944581|RGD:8552357
Biological ProcessGO:0007411axon guidancePax6IMPMGI:MGI:1856158MousePMID:11967891
Biological ProcessGO:0007411axon guidancePax6IMPMGI:MGI:1856158MousePMID:14586016
Biological ProcessGO:0007409axonogenesisPax6IMPMGI:MGI:1856158MousePMID:15514979
Biological ProcessGO:0001568blood vessel developmentPAX6IMPHumanPMID:7550230
Biological ProcessGO:0007420brain developmentPax6IMPMGI:MGI:1856155MousePMID:12196586
Biological ProcessGO:0007420brain developmentPax6IMPMGI:MGI:1856155MousePMID:10409504
Biological ProcessGO:0007420brain developmentPax6IMPRatPMID:9247338|RGD:731242
Biological ProcessGO:0043010camera-type eye developmentPax6IGIMGI:MGI:108564MousePMID:12183364
Biological ProcessGO:0043010camera-type eye developmentPax6IMPMGI:MGI:1934348MousePMID:11069887
Biological ProcessGO:0043010camera-type eye developmentPax6IMPMGI:MGI:1931308MousePMID:11062307
Biological ProcessGO:0043010camera-type eye developmentPax6IMPMGI:MGI:1856158MousePMID:16080917
Biological ProcessGO:0043010camera-type eye developmentPax6IGIMGI:MGI:102764MousePMID:12072567
Biological ProcessGO:0043010camera-type eye developmentPax6IMPMGI:MGI:1856158MousePMID:12648492
Biological ProcessGO:0043010camera-type eye developmentPax6IMPMGI:MGI:1934347MousePMID:12756174
Biological ProcessGO:0030154cell differentiationPax6IMPMGI:MGI:1856155MousePMID:15031110
Biological ProcessGO:0030154cell differentiationPax6IMPMGI:MGI:1856155MousePMID:24528677
Biological ProcessGO:0045165cell fate commitmentPax6IMPMGI:MGI:1856155MousePMID:15878992
Biological ProcessGO:0045165cell fate commitmentPax6IGIMGI:MGI:1100526MousePMID:15229646
Biological ProcessGO:0001709cell fate determinationPax6IMPMGI:MGI:1934347MousePMID:12756174
Biological ProcessGO:0008283cell population proliferationPax6IMPMGI:MGI:3521718MousePMID:15548580
Biological ProcessGO:0044344cellular response to fibroblast growth factor stimulusPax6IEPRatPMID:18189319|RGD:8552378
Biological ProcessGO:0071333cellular response to glucose stimulusPax6IEPRatPMID:21818840|RGD:8552375
Biological ProcessGO:0071333cellular response to glucose stimulusPax6IEPRatPMID:24953606|RGD:12790973
Biological ProcessGO:0032869cellular response to insulin stimulusPax6IEPRatPMID:18189319|RGD:8552378
Biological ProcessGO:1990830cellular response to leukemia inhibitory factorPax6IEPMousePMID:20439489
Biological ProcessGO:0071380cellular response to prostaglandin E stimulusPax6IEPRatPMID:23257891|RGD:8552382
Biological ProcessGO:0071466cellular response to xenobiotic stimulusPax6IEPRatPMID:19619535|RGD:8552332
Biological ProcessGO:0007417central nervous system developmentPax6IEPRatPMID:16237179|RGD:1578467
Biological ProcessGO:0021549cerebellum developmentPax6IEPRatPMID:11688562|RGD:8552644
Biological ProcessGO:0021987cerebral cortex developmentPax6IMPMousePMID:30186101
Biological ProcessGO:0021796cerebral cortex regionalizationPax6IMPMousePMID:30186101
Biological ProcessGO:0021796cerebral cortex regionalizationPax6IMPMGI:MGI:1856155MousePMID:12764040
Biological ProcessGO:0021796cerebral cortex regionalizationPax6IMPMousePMID:23431145
Biological ProcessGO:0006338chromatin remodelingPax6IMPMousePMID:30186101
Biological ProcessGO:0021902commitment of neuronal cell to specific neuron type in forebrainPax6IMPMGI:MGI:1856158MousePMID:11124115
Biological ProcessGO:0061303cornea development in camera-type eyePAX6IMPHumanPMID:7550230
Biological ProcessGO:0061303cornea development in camera-type eyepax6bIMPZFIN:ZDB-GENO-100610-2ZfishPMID:25692557
Biological ProcessGO:0080111DNA demethylationPax6IMPMousePMID:30186101
Biological ProcessGO:0006306DNA methylationPax6IMPMousePMID:30186101
Biological ProcessGO:0006351DNA-templated transcriptionpax6aIDAZfishPMID:9831649|ZFIN:ZDB-PUB-990105-4
Biological ProcessGO:0006351DNA-templated transcriptionpax6bIDAZfishPMID:18282108|ZFIN:ZDB-PUB-080306-6
Biological ProcessGO:0009950dorsal/ventral axis specificationPax6IMPMGI:MGI:1934347MousePMID:10588713
Biological ProcessGO:0009950dorsal/ventral axis specificationPax6IMPMGI:MGI:1856155MousePMID:10588713
Biological ProcessGO:0009953dorsal/ventral pattern formationPax6IMPMGI:MGI:1856155MousePMID:15548580
Biological ProcessGO:0009953dorsal/ventral pattern formationPax6IMPMGI:MGI:2156741MousePMID:15548580
Biological ProcessGO:0009953dorsal/ventral pattern formationPax6IMPMGI:MGI:1856155MousePMID:15878992
Biological ProcessGO:0009953dorsal/ventral pattern formationPax6IMPMGI:MGI:3521718MousePMID:15548580
Biological ProcessGO:0048596embryonic camera-type eye morphogenesisPax6IGIMGI:MGI:1306784MousePMID:18653562
Biological ProcessGO:0035883enteroendocrine cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:32867764
Biological ProcessGO:0021538epithalamus developmentpax6bIGIZFIN:ZDB-MRPHLNO-041116-1,ZFIN:ZDB-MRPHLNO-041116-2ZfishPMID:24528677
Biological ProcessGO:0021538epithalamus developmentpax6aIGIZFIN:ZDB-MRPHLNO-041116-1,ZFIN:ZDB-MRPHLNO-041116-2ZfishPMID:24528677
Biological ProcessGO:0002064epithelial cell developmentPax6IMPRatPMID:19393751|RGD:8552646
Biological ProcessGO:0000132establishment of mitotic spindle orientationPax6IMPMGI:MGI:1856155MousePMID:22031545
Biological ProcessGO:0001654eye developmentpax6bIMPZFIN:ZDB-MRPHLNO-080925-5ZfishPMID:18282108
Biological ProcessGO:0001654eye developmentpax6bIMPZFIN:ZDB-GENO-100610-2ZfishPMID:18282108
Biological ProcessGO:0001654eye developmentpax6bIMPZFIN:ZDB-MRPHLNO-080925-4ZfishPMID:18282108
Biological ProcessGO:0042462eye photoreceptor cell developmentPax6IMPMGI:MGI:1856158MousePMID:12648492
Biological ProcessGO:0030900forebrain developmentPax6IMPMGI:MGI:1856155MousePMID:15758185
Biological ProcessGO:0030900forebrain developmentPax6IMPMGI:MGI:1856158MousePMID:15514979
Biological ProcessGO:0030900forebrain developmentPax6IMPMGI:MGI:3521718MousePMID:15548580
Biological ProcessGO:0030900forebrain developmentpax6aIGIZFIN:ZDB-GENE-980526-167,ZFIN:ZDB-GENE-980526-40ZfishPMID:12917294
Biological ProcessGO:0021798forebrain dorsal/ventral pattern formationPax6IMPMGI:MGI:1856158MousePMID:11124115
Biological ProcessGO:0021798forebrain dorsal/ventral pattern formationPax6IMPMGI:MGI:1856155MousePMID:11050125
Biological ProcessGO:0021798forebrain dorsal/ventral pattern formationPax6IMPMGI:MGI:1856155MousePMID:24528677
Biological ProcessGO:0021798forebrain dorsal/ventral pattern formationPax6IMPMGI:MGI:1856155MousePMID:18701439
Biological ProcessGO:0021905forebrain-midbrain boundary formationPax6IMPMGI:MGI:1856155MousePMID:9169845
Biological ProcessGO:0021905forebrain-midbrain boundary formationPax6IMPMGI:MGI:1856158MousePMID:9169845
Biological ProcessGO:0010467gene expressionPax6IMPMousePMID:24488179
Biological ProcessGO:0010467gene expressionPax6IMPMousePMID:30186101
Biological ProcessGO:0002067glandular epithelial cell differentiationPax6IMPMGI:MGI:1856158MousePMID:16080917
Biological ProcessGO:0042593glucose homeostasisPAX6IMPHumanPMID:11756345
Biological ProcessGO:0021986habenula developmentPax6IMPMGI:MGI:1856155MousePMID:24528677
Biological ProcessGO:0021986habenula developmentpax6aIMPZFIN:ZDB-MRPHLNO-171212-2ZfishPMID:27387288
Biological ProcessGO:0030902hindbrain developmentPax6IDARatPMID:11880342|RGD:729590
Biological ProcessGO:0030902hindbrain developmentPax6IMPRatPMID:20082710|RGD:8552345
Biological ProcessGO:0030902hindbrain developmentpax6bIMPZFIN:ZDB-MRPHLNO-041116-2ZfishPMID:17010333
Biological ProcessGO:0030902hindbrain developmentpax6aIMPZFIN:ZDB-MRPHLNO-041116-1ZfishPMID:17010333
Biological ProcessGO:1901142insulin metabolic processPax6IMPRatPMID:21069736|RGD:8552358
Biological ProcessGO:0022027interkinetic nuclear migrationPax6IMPRatPMID:17825043|RGD:8552353
Biological ProcessGO:0061072iris morphogenesisPAX6IMPHumanPMID:7550230
Biological ProcessGO:0030216keratinocyte differentiationPax6IMPMGI:MGI:1856158MousePMID:16080917
Biological ProcessGO:0032808lacrimal gland developmentPax6IMPMGI:MGI:1856155MousePMID:10821755
Biological ProcessGO:0098598learned vocalization behavior or vocal learningPax6IMPRatPMID:21203536|RGD:8552339
Biological ProcessGO:0002088lens development in camera-type eyePax6IMPMGI:MGI:2156742MousePMID:6877261
Biological ProcessGO:0002088lens development in camera-type eyepax6bIMPZFIN:ZDB-GENO-070917-1ZfishPMID:17397257
Biological ProcessGO:0002089lens morphogenesis in camera-type eyepax6bIMPZFIN:ZDB-MRPHLNO-100610-5ZfishPMID:20177065
Biological ProcessGO:0002089lens morphogenesis in camera-type eyepax6bIMPZFIN:ZDB-MRPHLNO-100610-4ZfishPMID:20177065
Biological ProcessGO:0002089lens morphogenesis in camera-type eyepax6bIMPZFIN:ZDB-MRPHLNO-100610-4,ZFIN:ZDB-MRPHLNO-100610-7ZfishPMID:20177065
Biological ProcessGO:0002089lens morphogenesis in camera-type eyepax6bIMPZFIN:ZDB-MRPHLNO-100610-5,ZFIN:ZDB-MRPHLNO-100610-6ZfishPMID:20177065
Biological ProcessGO:0002089lens morphogenesis in camera-type eyepax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:20177065
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationPax6IMPMGI:MGI:1856158MousePMID:16080917
Biological ProcessGO:2000178negative regulation of neural precursor cell proliferationPax6IMPMGI:MGI:1856155MousePMID:23622063
Biological ProcessGO:0007406negative regulation of neuroblast proliferationPax6IMPMGI:MGI:3521718MousePMID:15548580
Biological ProcessGO:0045665negative regulation of neuron differentiationPax6IGIMGI:MGI:95728MousePMID:16950124
Biological ProcessGO:0001933negative regulation of protein phosphorylationPax6IMPMGI:MGI:1856155MousePMID:16497297
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIPax6IDAMouseMGI:MGI:6478056|PMID:23990468
Biological ProcessGO:0001755neural crest cell migrationPax6IMPRatPMID:9079035|RGD:8552342
Biological ProcessGO:0001755neural crest cell migrationpax6aIGIZFIN:ZDB-GENO-220927-6ZfishPMID:32555736
Biological ProcessGO:0001755neural crest cell migrationpax6bIGIZFIN:ZDB-GENO-220927-6ZfishPMID:32555736
Biological ProcessGO:0061351neural precursor cell proliferationPax6IMPMGI:MGI:1856155MousePMID:23622063
Biological ProcessGO:0061351neural precursor cell proliferationPax6IMPRatPMID:22944581|RGD:8552357
Biological ProcessGO:0007405neuroblast proliferationPax6IMPMousePMID:18287938
Biological ProcessGO:0007405neuroblast proliferationPax6IMPMGI:MGI:3521718MousePMID:15548580
Biological ProcessGO:0030182neuron differentiationPax6IMPMousePMID:30186101
Biological ProcessGO:0030182neuron differentiationPax6IGIMGI:MGI:95728MousePMID:16950124
Biological ProcessGO:0001764neuron migrationPax6IMPMousePMID:30186101
Biological ProcessGO:0001764neuron migrationPax6IMPMGI:MGI:1856155MousePMID:15758185
Biological ProcessGO:0001764neuron migrationPax6IMPRatPMID:12534968|RGD:1358337
Biological ProcessGO:0021772olfactory bulb developmentPax6IMPRatPMID:14736749|RGD:8552333
Biological ProcessGO:0061034olfactory bulb mitral cell layer developmentPax6IMPRatPMID:14736749|RGD:8552333
Biological ProcessGO:0021778oligodendrocyte cell fate specificationPax6IMPMGI:MGI:1856155MousePMID:9828088
Biological ProcessGO:0021543pallium developmentPax6IMPMGI:MGI:1856158MousePMID:11124115
Biological ProcessGO:0003322pancreatic A cell developmentPAX6IMPHumanPMID:20592023
Biological ProcessGO:0003322pancreatic A cell developmentPax6IMPMouseMGI:MGI:4943812|PMID:20592023
Biological ProcessGO:0003322pancreatic A cell developmentPax6IMPRatPMID:20592023|RGD:8552352
Biological ProcessGO:0003310pancreatic A cell differentiationPax6IMPRatPMID:20592023|RGD:8552352
Biological ProcessGO:0003310pancreatic A cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:32867764
Biological ProcessGO:0003310pancreatic A cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:20177065
Biological ProcessGO:0003310pancreatic A cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-4ZfishPMID:20177065
Biological ProcessGO:0003311pancreatic D cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:32867764
Biological ProcessGO:0003311pancreatic D cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-4ZfishPMID:20177065
Biological ProcessGO:0003311pancreatic D cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-5ZfishPMID:20177065
Biological ProcessGO:0003311pancreatic D cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-4,ZFIN:ZDB-MRPHLNO-100610-7ZfishPMID:20177065
Biological ProcessGO:0003311pancreatic D cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-3ZfishPMID:20177065
Biological ProcessGO:0003311pancreatic D cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:20177065
Biological ProcessGO:0090104pancreatic epsilon cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:32867764
Biological ProcessGO:0090104pancreatic epsilon cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-4ZfishPMID:20177065
Biological ProcessGO:0090104pancreatic epsilon cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:20177065
Biological ProcessGO:0090104pancreatic epsilon cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-4,ZFIN:ZDB-MRPHLNO-100610-7ZfishPMID:20177065
Biological ProcessGO:0090104pancreatic epsilon cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-3ZfishPMID:20177065
Biological ProcessGO:0090104pancreatic epsilon cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-5ZfishPMID:20177065
Biological ProcessGO:0021983pituitary gland developmentPax6IMPMGI:MGI:1934347MousePMID:10588713
Biological ProcessGO:0021983pituitary gland developmentPax6IMPMGI:MGI:1856155MousePMID:10588713
Biological ProcessGO:0042660positive regulation of cell fate specificationPax6IMPRatPMID:11880342|RGD:729590
Biological ProcessGO:0008284positive regulation of cell population proliferationpax6aIMPZfishPMID:20152834|ZFIN:ZDB-PUB-100223-15
Biological ProcessGO:1904798positive regulation of core promoter bindingPAX6IDAHumanPMID:20725088
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionPAX6IMPHumanPMID:20592023
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionPAX6IDAHumanPMID:20725088
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionPax6IDAMouseMGI:MGI:4943812|PMID:20592023
Biological ProcessGO:0030858positive regulation of epithelial cell differentiationPax6IMPMGI:MGI:1856158MousePMID:16080917
Biological ProcessGO:0010628positive regulation of gene expressionPAX6IMPHumanPMID:20592023
Biological ProcessGO:0010628positive regulation of gene expressionPax6IMPMouseMGI:MGI:4943812|PMID:20592023
Biological ProcessGO:0010628positive regulation of gene expressionPax6IMPRatPMID:11222774|RGD:8552343
Biological ProcessGO:0010628positive regulation of gene expressionPax6IMPRatPMID:20592023|RGD:8552352
Biological ProcessGO:0070094positive regulation of glucagon secretionPax6IMPRatPMID:22778220|RGD:8552356
Biological ProcessGO:0120008positive regulation of glutamatergic neuron differentiationPax6IMPRatPMID:24030726|RGD:12790968
Biological ProcessGO:0002052positive regulation of neuroblast proliferationPax6IMPMousePMID:18287938
Biological ProcessGO:2001224positive regulation of neuron migrationPax6IGIRGD:11059RatPMID:11688562|RGD:8552644
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPAX6IMPHumanPMID:20592023
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IDAMouseMGI:MGI:5306308|PMID:16407227
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IDAMouseMGI:MGI:2662558|PMID:12756174
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IMPMouseMGI:MGI:4943812|PMID:20592023
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IDAMousePMID:15905411
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IGIMGI:MGI:1915344MousePMID:23643363
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IDAMousePMID:18287938
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IDAMousePMID:19749747
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IGIMGI:MGI:96785MousePMID:19146846
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIPax6IMPRatPMID:20592023|RGD:8552352
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIpax6bIDAZfishPMID:9831649
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIpax6aIDAZfishPMID:9831649
Biological ProcessGO:0033365protein localization to organellePax6IMPMGI:MGI:1856155MousePMID:16024294
Biological ProcessGO:0006468protein phosphorylationPax6IMPMGI:MGI:1856155MousePMID:16497297
Biological ProcessGO:0003002regionalizationPax6IMPMGI:MGI:1856155MousePMID:9169845
Biological ProcessGO:0003002regionalizationPax6IMPMGI:MGI:1856158MousePMID:9169845
Biological ProcessGO:0003002regionalizationPax6IMPMGI:MGI:1856155MousePMID:24528677
Biological ProcessGO:0009786regulation of asymmetric cell divisionPax6IMPMGI:MGI:1856155MousePMID:22031545
Biological ProcessGO:0030334regulation of cell migrationPax6IMPMGI:MGI:1856155MousePMID:10409504
Biological ProcessGO:0030334regulation of cell migrationPax6IMPMGI:MGI:1856155MousePMID:18701439
Biological ProcessGO:0010468regulation of gene expressionPax6IMPMousePMID:16919471
Biological ProcessGO:0010468regulation of gene expressionPax6IMPMGI:MGI:1856155MousePMID:12764040
Biological ProcessGO:0010468regulation of gene expressionPax6IMPMousePMID:18799682
Biological ProcessGO:0010468regulation of gene expressionpax6bIGIZFIN:ZDB-MRPHLNO-041116-1,ZFIN:ZDB-MRPHLNO-041116-2ZfishPMID:24528677
Biological ProcessGO:0010468regulation of gene expressionpax6aIGIZFIN:ZDB-MRPHLNO-041116-1,ZFIN:ZDB-MRPHLNO-041116-2ZfishPMID:24528677
Biological ProcessGO:0050767regulation of neurogenesisPax6IMPMGI:MGI:3521718MousePMID:15548580
Biological ProcessGO:0050767regulation of neurogenesisPax6IMPRatPMID:16164600|RGD:1601222
Biological ProcessGO:0045664regulation of neuron differentiationPax6IMPMGI:MGI:3521718MousePMID:15548580
Biological ProcessGO:0045664regulation of neuron differentiationPax6IDARatPMID:11880342|RGD:729590
Biological ProcessGO:0010975regulation of neuron projection developmentPax6IGIRGD:11059RatPMID:11688562|RGD:8552644
Biological ProcessGO:0048505regulation of timing of cell differentiationPax6IMPMGI:MGI:1856155MousePMID:9828088
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIPax6IMPMGI:MGI:1856155MousePMID:9230312
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIPax6IMPMGI:MGI:1856155MousePMID:19521500
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIpax6bIDAZfishPMID:18282108|ZFIN:ZDB-PUB-080306-6
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIpax6aIDAZfishPMID:9831649|ZFIN:ZDB-PUB-990105-4
Biological ProcessGO:0045471response to ethanolPax6IEPRatPMID:21073715|RGD:8552373
Biological ProcessGO:0009611response to woundingPAX6IEPHumanPMID:17982423
Biological ProcessGO:0060041retina development in camera-type eyePax6IGIMGI:MGI:96785MousePMID:19146846
Biological ProcessGO:0060041retina development in camera-type eyePax6IEPRatPMID:19012751|RGD:2311636
Biological ProcessGO:0042670retinal cone cell differentiationpax6aIMPZfishPMID:20152834|ZFIN:ZDB-PUB-100223-15
Biological ProcessGO:0060221retinal rod cell differentiationpax6aIMPZfishPMID:20152834|ZFIN:ZDB-PUB-100223-15
Biological ProcessGO:0021593rhombomere morphogenesisPax6IMPRatPMID:21501682|RGD:8552349
Biological ProcessGO:0007435salivary gland morphogenesisPax6IMPMGI:MGI:1856158MousePMID:11731698
Biological ProcessGO:1904937sensory neuron migrationPax6IMPRatPMID:16510508|RGD:12791011
Biological ProcessGO:0023019signal transduction involved in regulation of gene expressionPax6IDAMousePMID:18462699
Biological ProcessGO:0007224smoothened signaling pathwayPax6IDAMousePMID:18590716
Biological ProcessGO:0021510spinal cord developmentPax6IEPRatPMID:20195794|RGD:2325285
Biological ProcessGO:0021978telencephalon regionalizationPax6IMPMGI:MGI:1856155MousePMID:18701439
Biological ProcessGO:0006366transcription by RNA polymerase IIPax6IGIMGI:MGI:1915344MousePMID:23643363
Biological ProcessGO:0003309type B pancreatic cell differentiationPax6IMPMGI:MGI:1934347MousePMID:22764048
Biological ProcessGO:0003309type B pancreatic cell differentiationPax6IMPRatPMID:22403172|RGD:8552355
Biological ProcessGO:0003309type B pancreatic cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:32867764
Biological ProcessGO:0003309type B pancreatic cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-4ZfishPMID:20177065
Biological ProcessGO:0003309type B pancreatic cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-3ZfishPMID:20177065
Biological ProcessGO:0003309type B pancreatic cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-4,ZFIN:ZDB-MRPHLNO-100610-7ZfishPMID:20177065
Biological ProcessGO:0003309type B pancreatic cell differentiationpax6bIMPZFIN:ZDB-GENO-100507-7ZfishPMID:20177065
Biological ProcessGO:0003309type B pancreatic cell differentiationpax6bIMPZFIN:ZDB-MRPHLNO-100610-5ZfishPMID:20177065
Biological ProcessGO:0021517ventral spinal cord developmentPax6IMPMouseMGI:MGI:4834949|PMID:20844123

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory