Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAXIP1
  • Mouse genes Paxip1
  • Rat genes Paxip1
  • Zfish genes paxip1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Paxip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:O60356	Human	PMID:11940591
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q12888	Human	PMID:15456759
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P61964	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q15291	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q9BTK6	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q9UBL3	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P61964	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q15291	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q9BTK6	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q9UBL3	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P61964	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q15291	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q9UBL3	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q9BTK6	Human	PMID:19124460
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P61964	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:Q9UBL3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P61964	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P61964	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PAXIP1	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Paxip1	IPI	UniProtKB:Q12888|UniProtKB:Q9BTK6	Mouse	MGI:MGI:3718866|PMID:17500065
Molecular Function	GO:0005515	protein binding	Paxip1	IPI	UniProtKB:Q12888	Mouse	MGI:MGI:3767118|PMID:17925232
Molecular Function	GO:0005515	protein binding	Paxip1	IPI	UniProtKB:Q02650	Mouse	MGI:MGI:5013490|PMID:21552207
Molecular Function	GO:0005515	protein binding	Paxip1	IPI	UniProtKB:Q99L02	Mouse	MGI:MGI:5752090|PMID:26744420
Molecular Function	GO:0005515	protein binding	Paxip1	IPI	UniProtKB:P32114-2	Mouse	MGI:MGI:1934164|PMID:10908331
Molecular Function	GO:0005515	protein binding	Paxip1	IPI	UniProtKB:P32114	Mouse	MGI:MGI:1934164|PMID:10908331
Molecular Function	GO:0005515	protein binding	Paxip1	IPI	UniProtKB:Q12888|UniProtKB:Q9BTK6	Mouse	MGI:MGI:3844416|PMID:19124460
Cellular Component	GO:0035097	histone methyltransferase complex	PAXIP1	IDA		Human	PMID:17925232
Cellular Component	GO:0035097	histone methyltransferase complex	Paxip1	IDA		Mouse	PMID:17500065
Cellular Component	GO:0044666	MLL3/4 complex	PAXIP1	IPI		Human	PMID:23508102
Cellular Component	GO:0044666	MLL3/4 complex	PAXIP1	IDA		Human	PMID:17500065
Cellular Component	GO:0005634	nucleus	PAXIP1	IDA		Human	PMID:15456759
Cellular Component	GO:0005634	nucleus	PAXIP1	IDA		Human	PMID:17690115
Cellular Component	GO:0005634	nucleus	Paxip1	IDA		Mouse	MGI:MGI:4821506|PMID:20671152
Cellular Component	GO:0005634	nucleus	Paxip1	IDA		Mouse	PMID:17500065
Cellular Component	GO:0005634	nucleus	Paxip1	IDA		Mouse	PMID:10908331
Biological Process	GO:0060612	adipose tissue development	Paxip1	IMP		Mouse	MGI:MGI:4354659|PMID:19583951
Biological Process	GO:0060717	chorion development	Paxip1	IMP		Mouse	MGI:MGI:3814106|PMID:18710940
Biological Process	GO:0006974	DNA damage response	Paxip1	IMP		Mouse	MGI:MGI:3844416|PMID:19124460
Biological Process	GO:0006974	DNA damage response	Paxip1	IDA		Mouse	PMID:17500065
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	PAXIP1	IMP		Human	PMID:15456759
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	PAXIP1	IMP		Human	PMID:17690115
Biological Process	GO:0043542	endothelial cell migration	Paxip1	IMP		Mouse	MGI:MGI:3814106|PMID:18710940
Biological Process	GO:0051568	histone H3-K4 methylation	PAXIP1	IDA		Human	PMID:17178841
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	PAXIP1	IMP		Human	PMID:11940591
Biological Process	GO:0045830	positive regulation of isotype switching	Paxip1	IMP		Mouse	MGI:MGI:4821506|PMID:20671152
Biological Process	GO:0048304	positive regulation of isotype switching to IgG isotypes	Paxip1	IMP		Mouse	MGI:MGI:5752090|PMID:26744420
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Paxip1	IMP		Mouse	MGI:MGI:4887323|PMID:18353733
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	PAXIP1	IMP		Human	PMID:17925232
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	Paxip1	IMP		Mouse	MGI:MGI:4821506|PMID:20671152
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	Paxip1	IMP		Mouse	MGI:MGI:4354659|PMID:19583951
Biological Process	GO:1902749	regulation of cell cycle G2/M phase transition	Paxip1	IMP		Mouse	MGI:MGI:3844416|PMID:19124460
Biological Process	GO:0010212	response to ionizing radiation	PAXIP1	IDA		Human	PMID:15456759
Biological Process	GO:0001570	vasculogenesis	Paxip1	IMP		Mouse	MGI:MGI:3814106|PMID:18710940

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern