Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PBX2
  • Mouse genes Pbx2
  • Rat genes Pbx2
  • Zfish genes pbx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pbx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pbx2	IDA		Mouse	PMID:16672333
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PBX2	IDA		Human	PMID:19356220
Molecular Function	GO:0140297	DNA-binding transcription factor binding	PBX2	IPI	UniProtKB:P31268	Human	PMID:18973687
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:P31314	Human	PMID:19559479
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:P49639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q9H257	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:O60682	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:P09067	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:P20719	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:P31274	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q00444	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q13515	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q504Y3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q5JVL4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q5PSV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q5TAB7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q86W92	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q8TDH9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q96GN5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:Q96SQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBX2	IPI	UniProtKB:P31314	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Pbx2	IPI	UniProtKB:Q15475	Mouse	MGI:MGI:3044439|PMID:15141091
Molecular Function	GO:0005515	protein binding	Pbx2	IPI	PR:O70477	Mouse	PMID:10381567
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	PBX2	IDA		Human	PMID:12054735
Cellular Component	GO:0005634	nucleus	PBX2	IDA		Human	PMID:18973687
Cellular Component	GO:0005634	nucleus	Pbx2	IDA		Mouse	PMID:15087118
Cellular Component	GO:0005634	nucleus	Pbx2	IDA		Mouse	PMID:10842069
Cellular Component	GO:0005667	transcription regulator complex	Pbx2	IDA		Mouse	PMID:10381567
Biological Process	GO:0007420	brain development	pbx2	IMP		Zfish	PMID:12431378
Biological Process	GO:0055007	cardiac muscle cell differentiation	pbx2	IGI	ZFIN:ZDB-MRPHLNO-070529-1,ZFIN:ZDB-MRPHLNO-070529-2,ZFIN:ZDB-MRPHLNO-070529-3,ZFIN:ZDB-MRPHLNO-070529-4	Zfish	PMID:19607825
Biological Process	GO:0030326	embryonic limb morphogenesis	Pbx2	IGI	MGI:MGI:97495	Mouse	PMID:16672333
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	pbx2	IGI	ZFIN:ZDB-GENO-071026-2,ZFIN:ZDB-MRPHLNO-070529-1,ZFIN:ZDB-MRPHLNO-070529-3	Zfish	PMID:17634100
Biological Process	GO:0003007	heart morphogenesis	pbx2	IGI	ZFIN:ZDB-MRPHLNO-070529-1,ZFIN:ZDB-MRPHLNO-070529-2,ZFIN:ZDB-MRPHLNO-070529-3,ZFIN:ZDB-MRPHLNO-070529-4,ZFIN:ZDB-MRPHLNO-080930-4	Zfish	PMID:19607825
Biological Process	GO:0030901	midbrain development	pbx2	IGI	ZFIN:ZDB-GENO-071026-2,ZFIN:ZDB-MRPHLNO-070529-1,ZFIN:ZDB-MRPHLNO-070529-3	Zfish	PMID:17634100
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PBX2	IDA		Human	PMID:19356220
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pbx2	IDA		Mouse	PMID:16672333
Biological Process	GO:0009954	proximal/distal pattern formation	Pbx2	IGI	MGI:MGI:97495	Mouse	PMID:16672333
Biological Process	GO:0048741	skeletal muscle fiber development	pbx2	IGI	ZFIN:ZDB-MRPHLNO-070529-1,ZFIN:ZDB-MRPHLNO-070529-2,ZFIN:ZDB-MRPHLNO-070529-3,ZFIN:ZDB-MRPHLNO-070529-4,ZFIN:ZDB-MRPHLNO-071210-2,ZFIN:ZDB-MRPHLNO-071210-3	Zfish	PMID:17699609
Biological Process	GO:0048741	skeletal muscle fiber development	pbx2	IGI	ZFIN:ZDB-MRPHLNO-070529-1,ZFIN:ZDB-MRPHLNO-070529-2,ZFIN:ZDB-MRPHLNO-070529-3,ZFIN:ZDB-MRPHLNO-070529-4	Zfish	PMID:17699609
Biological Process	GO:0048741	skeletal muscle fiber development	pbx2	IGI	ZFIN:ZDB-GENE-980526-166,ZFIN:ZDB-MRPHLNO-070529-1,ZFIN:ZDB-MRPHLNO-070529-2,ZFIN:ZDB-MRPHLNO-070529-3,ZFIN:ZDB-MRPHLNO-070529-4	Zfish	PMID:17699609

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern