Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PCDH18
  • Mouse genes Pcdh18
  • Rat genes Pcdh18
  • Zfish genes pcdh18a,pcdh18b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pcdh18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PCDH18	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pcdh18	IPI	UniProtKB:P97318	Mouse	MGI:MGI:2154581|PMID:11716507
Molecular Function	GO:0005515	protein binding	pcdh18b	IPI	ZFIN:ZDB-GENE-030131-4426	Zfish	PMID:24371087
Cellular Component	GO:0005886	plasma membrane	pcdh18a	IDA		Zfish	PMID:18468594
Biological Process	GO:0007420	brain development	Pcdh18	IEP		Mouse	MGI:MGI:2154581|PMID:11716507
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	pcdh18a	IMP	ZFIN:ZDB-MRPHLNO-080804-5	Zfish	PMID:18468594
Biological Process	GO:0042074	cell migration involved in gastrulation	pcdh18a	IMP	ZFIN:ZDB-MRPHLNO-080804-4	Zfish	PMID:18468594
Biological Process	GO:0042074	cell migration involved in gastrulation	pcdh18a	IMP	ZFIN:ZDB-MRPHLNO-080804-5	Zfish	PMID:18468594
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	pcdh18a	IMP	ZFIN:ZDB-MRPHLNO-080804-5	Zfish	PMID:18468594
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	pcdh18a	IMP	ZFIN:ZDB-MRPHLNO-080804-4	Zfish	PMID:18468594
Biological Process	GO:0048812	neuron projection morphogenesis	pcdh18b	IMP	ZFIN:ZDB-MRPHLNO-140327-2	Zfish	PMID:24371087
Biological Process	GO:0048812	neuron projection morphogenesis	pcdh18b	IMP	ZFIN:ZDB-MRPHLNO-140327-3	Zfish	PMID:24371087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern