Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PCLAF
  • Mouse genes Pclaf
  • Rat genes Pclaf
  • Zfish genes pclaf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pclaf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	PCLAF	IDA		Human	PMID:23000965
Molecular Function	GO:0060090	molecular adaptor activity	PCLAF	EXP		Human	PMID:25762514
Molecular Function	GO:0060090	molecular adaptor activity	PCLAF	IDA		Human	PMID:25762514
Molecular Function	GO:0060090	molecular adaptor activity	PCLAF	IPI	UniProtKB:P12004	Human	PMID:25762514
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P12004	Human	PMID:21628590
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P38398	Human	PMID:21673012
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P12004	Human	PMID:23000965
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P12004	Human	PMID:25762514
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P12004	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P12004	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P12004	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PCLAF	IPI	UniProtKB:P54274-2	Human	PMID:32296183
Cellular Component	GO:0005813	centrosome	PCLAF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PCLAF	IDA		Human	PMID:21628590
Cellular Component	GO:0005634	nucleus	PCLAF	IDA		Human	PMID:21673012
Cellular Component	GO:0005634	nucleus	PCLAF	IDA		Human	PMID:23000965
Cellular Component	GO:0048471	perinuclear region of cytoplasm	PCLAF	IDA		Human	PMID:21673012
Biological Process	GO:0007098	centrosome cycle	PCLAF	IMP		Human	PMID:21673012
Biological Process	GO:0006974	DNA damage response	PCLAF	IDA		Human	PMID:21628590
Biological Process	GO:0006974	DNA damage response	PCLAF	IDA		Human	PMID:23000965
Biological Process	GO:0006260	DNA replication	PCLAF	IDA		Human	PMID:23000965
Biological Process	GO:0051726	regulation of cell cycle	PCLAF	IMP		Human	PMID:21628590
Biological Process	GO:0009411	response to UV	PCLAF	IDA		Human	PMID:23000965
Biological Process	GO:0019985	translesion synthesis	PCLAF	IMP		Human	PMID:23000965

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern