Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PCSK1N
  • Mouse genes Pcsk1n
  • Rat genes Pcsk1n
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pcsk1n

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004866	endopeptidase inhibitor activity	Pcsk1n	IDA		Rat	PMID:10632593|RGD:69973
Molecular Function	GO:0005515	protein binding	Pcsk1n	IPI	UniProtKB:P30731	Mouse	MGI:MGI:6141494|PMID:27117253
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	Pcsk1n	IDA		Mouse	PMID:10632593
Cellular Component	GO:0005615	extracellular space	Pcsk1n	IDA		Mouse	PMID:10632593
Cellular Component	GO:0005615	extracellular space	Pcsk1n	IDA		Rat	PMID:11742530|RGD:1642361
Cellular Component	GO:0030141	secretory granule	Pcsk1n	IDA		Mouse	PMID:10632593
Cellular Component	GO:0005802	trans-Golgi network	Pcsk1n	IDA		Mouse	PMID:10632593
Biological Process	GO:0007420	brain development	Pcsk1n	IEP		Rat	PMID:15935061|RGD:1642353
Biological Process	GO:0016486	peptide hormone processing	Pcsk1n	IDA		Mouse	PMID:10632593
Biological Process	GO:0009409	response to cold	Pcsk1n	IDA		Mouse	PMID:16631141
Biological Process	GO:0002021	response to dietary excess	Pcsk1n	IDA		Mouse	PMID:16631141

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern