Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PC
  • Mouse genes Pcx
  • Rat genes Pc
  • Zfish genes pcxa,pcxb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pcx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Pc	IDA		Rat	PMID:15507531|RGD:1601554
Molecular Function	GO:0005524	ATP binding	Pc	IDA		Rat	PMID:5773282|RGD:2302972
Molecular Function	GO:0009374	biotin binding	Pc	IDA		Rat	PMID:12949377|RGD:1601566
Molecular Function	GO:0009374	biotin binding	Pc	IMP		Rat	PMID:12949377|RGD:1601566
Molecular Function	GO:0031406	carboxylic acid binding	Pc	IDA		Rat	PMID:15507531|RGD:1601554
Molecular Function	GO:0042802	identical protein binding	PC	IPI	UniProtKB:P11498	Human	PMID:18297087
Molecular Function	GO:0042802	identical protein binding	PC	IPI	UniProtKB:P11498	Human	PMID:34547241
Molecular Function	GO:0005515	protein binding	PC	IPI	UniProtKB:Q03463:PRO_0000278740	Human	PMID:23861867
Molecular Function	GO:0005515	protein binding	PC	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:23861867
Molecular Function	GO:0005515	protein binding	PC	IPI	UniProtKB:P48163	Human	PMID:34547241
Molecular Function	GO:0004736	pyruvate carboxylase activity	PC	EXP		Human	PMID:12437512
Molecular Function	GO:0004736	pyruvate carboxylase activity	PC	IMP		Human	PMID:9585002
Molecular Function	GO:0004736	pyruvate carboxylase activity	Pcx	IMP	MGI:MGI:6382162	Mouse	PMID:31006591
Molecular Function	GO:0004736	pyruvate carboxylase activity	Pc	IMP		Rat	PMID:12949377|RGD:1601566
Molecular Function	GO:0004736	pyruvate carboxylase activity	Pc	IDA		Rat	PMID:15507531|RGD:1601554
Molecular Function	GO:0004736	pyruvate carboxylase activity	Pc	IDA		Rat	PMID:4353083|RGD:2302851
Molecular Function	GO:0004736	pyruvate carboxylase activity	Pc	IDA		Rat	PMID:5773282|RGD:2302972
Molecular Function	GO:0004736	pyruvate carboxylase activity	Pc	IDA		Rat	PMID:6049928|RGD:2302971
Cellular Component	GO:0005737	cytoplasm	PC	IDA		Human	PMID:23861867
Cellular Component	GO:0005737	cytoplasm	PC	IDA		Human	PMID:34547241
Cellular Component	GO:0005743	mitochondrial inner membrane	Pcx	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005759	mitochondrial matrix	Pcx	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005739	mitochondrion	PC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	PC	IDA		Human	PMID:16729965
Cellular Component	GO:0005739	mitochondrion	Pcx	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Pcx	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005739	mitochondrion	Pcx	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Pc	IDA		Rat	PMID:5773282|RGD:2302972
Cellular Component	GO:0005739	mitochondrion	Pc	IDA		Rat	PMID:6049928|RGD:2302971
Biological Process	GO:0006094	gluconeogenesis	Pcx	IMP		Mouse	PMID:23423574
Biological Process	GO:0006094	gluconeogenesis	Pcx	IMP	MGI:MGI:6382162	Mouse	PMID:31006591
Biological Process	GO:0006094	gluconeogenesis	Pcx	IMP	MGI:MGI:2449284	Mouse	PMID:10938127
Biological Process	GO:0006094	gluconeogenesis	Pc	IDA		Rat	PMID:4353083|RGD:2302851
Biological Process	GO:0006094	gluconeogenesis	Pc	IDA		Rat	PMID:6049928|RGD:2302971
Biological Process	GO:0046959	habituation	pcxa	IMP	ZFIN:ZDB-GENO-150624-9	Zfish	PMID:25754827
Biological Process	GO:0006734	NADH metabolic process	PC	IDA		Human	PMID:34547241
Biological Process	GO:0006739	NADP metabolic process	PC	IDA		Human	PMID:34547241
Biological Process	GO:0010629	negative regulation of gene expression	PC	IMP		Human	PMID:23861867
Biological Process	GO:0006107	oxaloacetate metabolic process	Pc	IDA		Rat	PMID:15507531|RGD:1601554
Biological Process	GO:0006107	oxaloacetate metabolic process	Pc	IDA		Rat	PMID:5773282|RGD:2302972
Biological Process	GO:0006107	oxaloacetate metabolic process	Pc	IDA		Rat	PMID:6049928|RGD:2302971
Biological Process	GO:0044794	positive regulation by host of viral process	PC	IMP		Human	PMID:23861867
Biological Process	GO:0071073	positive regulation of phospholipid biosynthetic process	Pc	IMP		Rat	PMID:23357280|RGD:10047307
Biological Process	GO:0006090	pyruvate metabolic process	Pc	IDA		Rat	PMID:15507531|RGD:1601554
Biological Process	GO:0006090	pyruvate metabolic process	Pc	IDA		Rat	PMID:5773282|RGD:2302972
Biological Process	GO:0006090	pyruvate metabolic process	Pc	IDA		Rat	PMID:6049928|RGD:2302971
Biological Process	GO:0046686	response to cadmium ion	pcxb	IEP		Zfish	PMID:16799861
Biological Process	GO:0019076	viral release from host cell	PC	IMP		Human	PMID:23861867
Biological Process	GO:0019074	viral RNA genome packaging	PC	IMP		Human	PMID:23861867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern